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Approaches for testing sets of variants, such as a set of rare or common variants within a gene or pathway, for association with complex traits are important. In particular, set tests allow for aggregation of weak signal within a set, can…

Genomics · Quantitative Biology 2013-05-28 Jennifer Listgarten , Christoph Lippert , Eun Yong Kang , Jing Xiang , Carl M. Kadie , David Heckerman

Motivation: Combining the results of different experiments to exhibit complex patterns or to improve statistical power is a typical aim of data integration. The starting point of the statistical analysis often comes as sets of p-values…

Methodology · Statistics 2021-12-02 Tristan Mary-Huard , Sarmistha Das , Indranil Mukhopadhyay , Stéphane Robin

In this paper, we present a conditional gradient type (CGT) method for solving a class of composite optimization problems where the objective function consists of a (weakly) smooth term and a (strongly) convex regularization term. While…

Optimization and Control · Mathematics 2018-01-03 Saeed Ghadimi

In a split conformal framework with $K$ classes, a calibration sample of $n$ labeled examples is observed for inference on the label of a new unlabeled example. We explore the setting where a `batch' of $m$ independent such unlabeled…

Methodology · Statistics 2025-03-19 Ulysse Gazin , Ruth Heller , Etienne Roquain , Aldo Solari

Disjunct matrices, also known as cover-free families and superimposed codes, are combinatorial arrays widely used in group testing. Among their variants, those that satisfy an additional combinatorial property called inclusiveness form a…

Information Theory · Computer Science 2026-01-15 Yuto Mizunuma , Yuichiro Fujiwara

The Neyman-Pearson (NP) binary classification paradigm constrains the more severe type of error (e.g., the type I error) under a preferred level while minimizing the other (e.g., the type II error). This paradigm is suitable for…

Methodology · Statistics 2022-06-07 Jingming Wang , Lucy Xia , Zhigang Bao , Xin Tong

In network tomography, one goal is to identify a small set of failed links in a network, by sending a few packets through the network and seeing which reach their destination. This problem can be seen as a variant of combinatorial group…

Information Theory · Computer Science 2018-09-12 Bruce Spang , Mary Wootters

Test response compaction for integrated circuits (ICs) with scan-based design-for-testability (DFT) support in the presence of unknown logic values (Xs) is investigated from a combinatorial viewpoint. The theoretical foundations of X-codes,…

Information Theory · Computer Science 2015-08-04 Yuichiro Fujiwara , Charles J. Colbourn

We study the problem of clustering a set of items based on bandit feedback. Each of the $n$ items is characterized by a feature vector, with a possibly large dimension $d$. The items are partitioned into two unknown groups such that items…

Machine Learning · Statistics 2025-03-19 Maximilian Graf , Victor Thuot , Nicolas Verzelen

We have a large number of samples and we want to find the infected ones using as few number of tests as possible. We can use group testing which tells about a small group of people whether at least one of them is infected. Group testing is…

Quantitative Methods · Quantitative Biology 2020-05-07 Endre Csóka

We discuss two non-standard models of nonadaptive combinatorial search which develop the conventional disjunct search model for a small number of defective elements contained in a finite ground set or a population. The first model is called…

Information Theory · Computer Science 2014-01-30 A. G. D'yachkov , A. J. Macula , D. C. Torney , P. A. Vilenkin

We present a new optimization method for the group selection problem in linear regression. In this problem, predictors are assumed to have a natural group structure and the goal is to select a small set of groups that best fits the…

Methodology · Statistics 2024-04-23 Anant Mathur , Sarat Moka , Benoit Liquet , Zdravko Botev

Benefiting from the intrinsic supervision information exploitation capability, contrastive learning has achieved promising performance in the field of deep graph clustering recently. However, we observe that two drawbacks of the positive…

Machine Learning · Computer Science 2023-01-04 Xihong Yang , Yue Liu , Sihang Zhou , Siwei Wang , Wenxuan Tu , Qun Zheng , Xinwang Liu , Liming Fang , En Zhu

Unit testing is critical to the software development process, ensuring the correctness of basic programming units in a program (e.g., a method). Search-based software testing (SBST) is an automated approach to generating test cases. SBST…

Software Engineering · Computer Science 2024-01-05 Zhichao Zhou , Yuming Zhou , Chunrong Fang , Zhenyu Chen , Xiapu Luo , Jingzhu He , Yutian Tang

Consider a collection of objects, some of which may be `bad', and a test which determines whether or not a given sub-collection contains no bad objects. The non-adaptive pooling (or group testing) problem involves identifying the bad…

Combinatorics · Mathematics 2016-09-06 David J. Balding , David C. Torney

We discuss a general approach to handling "multiple hypotheses" testing in the case when a particular hypothesis states that the vector of parameters identifying the distribution of observations belongs to a convex compact set associated…

Statistics Theory · Mathematics 2016-02-24 A. Goldenshluger , A. Juditski , A. Nemirovski

The increasing interest in subpopulation analysis has led to the development of various new trial designs and analysis methods in the fields of personalized medicine and targeted therapies. In this paper, subpopulations are defined in terms…

Methodology · Statistics 2020-12-01 Roland Gerard Gera , Tim Friede

Collective graphical models exploit inter-instance associative dependence to output more accurate labelings. However existing models support very limited kind of associativity which restricts accuracy gains. This paper makes two major…

Artificial Intelligence · Computer Science 2009-07-07 Rahul Gupta , Sunita Sarawagi , Ajit A. Diwan

Context: Software has become an innovative solution nowadays for many applications and methods in science and engineering. Ensuring the quality and correctness of software is challenging because each program has different configurations and…

Software Engineering · Computer Science 2019-04-10 Bestoun S. Ahmed , Taib Sh. Abdulsamad , Moayad Y. Potrus

This paper presents a cumulative multi-niching genetic algorithm (CMN GA), designed to expedite optimization problems that have computationally-expensive multimodal objective functions. By never discarding individuals from the population,…

Neural and Evolutionary Computing · Computer Science 2013-04-03 Matthew Hall
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