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Nuclear magnetic resonance (NMR) experiments on subnanoliter (sub-nL) volumes are hindered by the limited sensitivity of the detector and the difficulties in positioning and holding such small samples in proximity of the detector. Here, we…

Biological Physics · Physics 2018-07-04 E. Montinaro , M. Grisi , M. C. Letizia , L. Pethö , M. A. M. Gijs , R. Guidetti , J. Michler , J. Brugger , G. Boero

Quantum sensors based on nitrogen-vacancy centers in diamond have emerged as a promising detection modality for nuclear magnetic resonance (NMR) spectroscopy owing to their micron-scale detection volume and non-inductive based detection. A…

Combining microfluidic devices with nuclear magnetic resonance (NMR) has the potential of unlocking their vast sample handling and processing operation space for use with the powerful analytics provided by NMR. One particularly challenging…

A novel approach for automated high throughput NMR spectroscopy with improved mass-sensitivity is accomplished by integrating microfluidic technologies and micro-NMR resonators. A flow system is utilized to transport a sample of interest…

Instrumentation and Detectors · Physics 2021-04-20 Omar Nassar , Mazin Jouda , Michael Rapp , Dario Mager , Jan G. Korvink , Neil MacKinnon

Despite its versatility and high chemical specificity, conventional NMR spectroscopy is limited in measurement throughput due to the need for high-homogeneity magnetic fields, necessitating sequential sample analysis, and bulky devices.…

Instrumentation and Detectors · Physics 2024-07-02 Blake Andrews , Matthew Lai , Zhen Wang , Norihisa Kato , Michael Tayler , Emanuel Druga , Ashok Ajoy

Nanoscale nuclear magnetic resonance (NMR) signals can be measured through hyperfine interaction to paramagnetic electron sensor spins. A heterodyne approach is widely used to overcome the electron spin lifetime limit in spectral…

We have developed an easy to construct, non-resonant wideband NMR probe. The probe is of the saddle coil geometry and is designed such that the coil itself forms a transmission line. The probe thus requires no tuning or matching elements.…

Instrumentation and Detectors · Physics 2007-10-02 D. Murphree , S. B. Cahn , D. Rahmlow , D. DeMille

We report on the realization of a high sensitivity RF noise measurement scheme to study small current fluctuations of mesoscopic systems at milliKelvin temperatures. The setup relies on the combination of an interferometric ampli- fication…

Mesoscale and Nanoscale Physics · Physics 2011-03-07 François D. Parmentier , Adrien Mahé , Anne Denis , Jean-Marc Berroir , D. Christian Glattli , Bernard Plaçais , Gwendal Fève

The design and performance of a low-noise, modular cryogenic probe, applicable to a wide range of measurements over a broad range of working frequencies, temperatures, and magnetic fields is presented. The design of the probe facilitates…

Other Condensed Matter · Physics 2022-10-13 Erick Garcia , Calvin Bales , William Patterson , Alexander Zaslavsky , Vesna F. Mitrović

We show that high-resolution NMR can reach picomole sensitivity for micromolar concentrations of analyte by combining parahydrogen induced hyperpolarisation (PHIP)with a high-sensitivity transmission line micro-detector. The para-enriched…

Chemical Physics · Physics 2019-05-20 James Eills , William Hale , Manvendra Sharma , Matheus Rossetto , Malcolm H. Levitt , Marcel Utz

Nuclear magnetic resonance (NMR) spectroscopy is a powerful technique to study local magnetism in a variety of materials. However, the inherently low sensitivity of conventional inductively detected solid state NMR typically requires a…

Mesoscale and Nanoscale Physics · Physics 2025-12-16 Louis Beaudoin , Aimé Verrier , Youcef A. Bioud , Mathieu Massicotte , Bertrand Reulet , Jeffrey A. Quilliam

Hyperpolarized nuclear magnetic resonance and lab-on-a-chip microfluidics are two dynamic, but until recently quite distinct, fields of research. Recent developments in both areas increased their synergistic overlap. By microfluidic…

Chemical Physics · Physics 2021-09-29 James Eills , William Hale , Marcel Utz

Scanning probe microscopy is one of the most versatile windows into the nanoworld, providing imaging access to a variety of sample properties, depending on the probe employed. Tunneling probes map electronic properties of samples, magnetic…

Mesoscale and Nanoscale Physics · Physics 2015-01-09 Thomas Häberle , Dominik Schmid-Lorch , Friedemann Reinhard , Jörg Wrachtrup

We demonstrate the design, fabrication and use of a dual electrode PMUT (Piezoelectric Micromachined Ultrasound Transducer) integrated with a microfluidic channel as a fluid density sensor in both static and dynamic density-change…

The combination of microwave and microfluidic technologies has the potential to enable wireless monitoring and interaction with bioparticles, facilitating in this way the exploration of a still largely uncharted territory at the…

Systems and Control · Electrical Eng. & Systems 2022-09-21 Cesar Palacios , Marc Jofre , Lluis Jofre , Jordi Romeu , Luis Jofre-Roca

We demonstrate an interface-sensitive NMR in a semiconducting nanostructure, where an NMR signal from the minute heterojunction region of a model heterojunction structure (In$_{0.48}$Ga$_{0.52}$P/GaAs) is detected by using nuclear…

Mesoscale and Nanoscale Physics · Physics 2017-12-13 Atsushi Goto , Kenjiro Hashi , Shinobu Ohki , Tadashi Shimizu

Magnetic-field and microwave-frequency modulated DNP experiments have been shown to yield improved enhancements over conventional DNP techniques, and even to shorten polarization build-up times. The resulting increase in signal-to-noise…

Instrumentation and Detectors · Physics 2015-12-23 Mallory L. Guy , Lihuang Zhu , Chandrasekhar Ramanathan

The implementation of nuclear magnetic resonance (NMR) at the nanoscale is a major challenge, as conventional systems require relatively large ensembles of spins and limit resolution to mesoscopic scales. New approaches based on quantum…

This study introduces a dual-band plasmonic absorber designed for simultaneous sensing applications in the near-infrared (NIR) and mid-infrared (MIR) regions. The absorber, composed of silver nanostructures on a metal plate with a…

Optics · Physics 2024-11-20 Ayon Sarker , Sajid Muhaimin Choudhury

Here we propose double-coil setup to allow high signal-to-noise ratio broad-range heteronuclear magnetic resonance imaging experiments: two independent coils, one of them tuned to $^{1}$H frequency to perform anatomical $^{1}$H imaging, and…

Medical Physics · Physics 2020-03-17 V. A. Ivanov , A. A. Hurshkainen , G. A. Solomakha , M. A. Zubkov
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