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Neurodevelopmental disorders such as Fragile X Syndrome (FXS) and Autism Spectrum Disorder (ASD) are characterized by disrupted cortical oscillatory activity, particularly in the alpha and gamma frequency bands. These abnormalities are…

Neurons and Cognition · Quantitative Biology 2025-11-14 Zag ElSayed , Grace Westerkamp , Jack Yanchen Liu , Ernest Pedapati

The brain is often studied from a network perspective, where functional activity is assessed using functional Magnetic Resonance Imaging (fMRI) to estimate connectivity between predefined neuronal regions. Functional connectivity can be…

Applications · Statistics 2025-07-22 Olivier Bisson , Yanis Aeschlimann , Samuel Deslauriers-Gauthier , Xavier Pennec

Functional Magnetic Resonance Images acquired during resting-state provide information about the functional organization of the brain through measuring correlations between brain areas. Independent components analysis is the reference…

Neurons and Cognition · Quantitative Biology 2014-12-15 Alexandre Abraham , Elvis Dohmatob , Bertrand Thirion , Dimitris Samaras , Gael Varoquaux

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…

There is increasing interest in learning how human brain networks vary as a function of a continuous trait, but flexible and efficient procedures to accomplish this goal are limited. We develop a Bayesian semiparametric model, which…

Methodology · Statistics 2017-02-02 Lu Wang , Daniele Durante , Rex E. Jung , David B. Dunson

The field of neuroimaging has truly become data rich, and novel analytical methods capable of gleaning meaningful information from large stores of imaging data are in high demand. Those methods that might also be applicable on the level of…

Multivariate Pattern (MVP) classification holds enormous potential for decoding visual stimuli in the human brain by employing task-based fMRI data sets. There is a wide range of challenges in the MVP techniques, i.e. decreasing noise and…

Machine Learning · Statistics 2016-12-28 Muhammad Yousefnezhad , Daoqiang Zhang

In neuroimaging data analysis, Gaussian graphical models are often used to model statistical dependencies across spatially remote brain regions known as functional connectivity. Typically, data is collected across a cohort of subjects and…

Machine Learning · Statistics 2015-12-08 Ricardo Pio Monti , Christoforos Anagnostopoulos , Giovanni Montana

In neuroimaging, extensive post-processing of resting-state functional MRI (rfMRI) data is necessary for its application and investigation in relation to brain-behavior associations. Such post-processing is used to derive brain…

Computational Geometry · Computer Science 2025-09-11 Ty Easley , Kevin Freese , Elizabeth Munch , Janine Bijsterbosch

In the recent past, psychological stress has been increasingly observed in humans, and early detection is crucial to prevent health risks. Stress detection using on-device deep learning algorithms has been on the rise owing to advancements…

Machine Learning · Computer Science 2020-12-07 Abhijith Ragav , Gautham Krishna Gudur

In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

Neurons and Cognition · Quantitative Biology 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq

Mixed membership models, or partial membership models, are a flexible unsupervised learning method that allows each observation to belong to multiple clusters. In this paper, we propose a Bayesian mixed membership model for functional data.…

We present a statistical framework that jointly models brain shape and functional connectivity, which are two complex aspects of the brain that have been classically studied independently. We adopt a Riemannian modeling approach to account…

Methodology · Statistics 2024-04-26 Eardi Lila , John A. D. Aston

Time-varying networks are fast emerging in a wide range of scientific and business disciplines. Most existing dynamic network models are limited to a single-subject and discrete-time setting. In this article, we propose a mixed-effect…

Methodology · Statistics 2018-06-12 Jingfei Zhang , Will Wei Sun , Lexin Li

Functional connectivity (FC) derived from functional magnetic resonance imaging (fMRI) data offers vital insights for understanding brain function and neurological and psychiatric disorders. Unsupervised clustering methods are desired to…

Methodology · Statistics 2025-12-04 Yixi Xu , Yi Zhao

In multi-condition EEG experiments, brain activity is recorded as subjects perform various tasks or are exposed to different stimuli. The recorded signals are commonly transformed into time-frequency representations, which often display…

Methodology · Statistics 2025-07-29 Xiaomeng Ju , Thaddeus Tarpey , Hyung G Park

Experiments that study neural encoding of stimuli at the level of individual neurons typically choose a small set of features present in the world --- contrast and luminance for vision, pitch and intensity for sound --- and assemble a…

Machine Learning · Statistics 2016-11-22 Xin , Chen , Jeffrey M Beck , John M Pearson

Dynamic networks have been increasingly used to characterize brain connectivity that varies during resting and task states. In such characterizations, a connectivity network is typically measured at each time point for a subject over a…

Methodology · Statistics 2023-03-23 Maoyu Zhang , Biao Cai , Wenlin Dai , Dehan Kong , Hongyu Zhao , Jingfei Zhang

In this work we focus on examination and comparison of whole-brain functional connectivity patterns measured with fMRI across experimental conditions. Direct examination and comparison of condition-specific matrices is challenging due to…

Applications · Statistics 2013-01-02 Svetlana V. Shinkareva , Vladimir Gudkov , Jing Wang

Task-based fMRI provides a direct readout of task-evoked neural dynamics, but it is expensive and difficult to acquire at scale, motivating rest-to-task synthesis from widely available resting-state fMRI (rsfMRI). We propose FM-fMRI, an…

Machine Learning · Computer Science 2026-05-27 Peiyu Duan , Jiyao Wang , Nicha C. Dvornek , Junlin Yang , Ziqi Gao , Lawrence H. Staib , James S. Duncan