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The latent class model is a widely used mixture model for multivariate discrete data. Besides the existence of qualitatively heterogeneous latent classes, real data often exhibit additional quantitative heterogeneity nested within each…

Methodology · Statistics 2025-01-23 Zhongyuan Lyu , Ling Chen , Yuqi Gu

Accurate and early prediction of a disease allows to plan and improve a patient's quality of future life. During pandemic situations, the medical decision becomes a speed challenge in which physicians have to act fast to diagnose and…

Machine Learning · Computer Science 2022-06-09 Pierluigi Costanzo , Kalia Orphanou

Sepsis, a critical condition from the body's response to infection, poses a major global health crisis affecting all age groups. Timely detection and intervention are crucial for reducing healthcare expenses and improving patient outcomes.…

Machine Learning · Computer Science 2024-07-12 MohammadAmin Ansari Khoushabar , Parviz Ghafariasl

Latent class growth analysis is a popular approach to identify underlying subpopulations. Several implementations, such as LCGA (Mplus), Proc Traj (SAS) and lcmm (R) are specially designed for this purpose. Motivated by data collection of…

Applications · Statistics 2021-08-17 Jianhui Gao , Aliza Panjwani , Madeline Li , Osvaldo Espin-Garcia

Amyotrophic Lateral Sclerosis (ALS) is characterized as a rapidly progressive neurodegenerative disease that presents individuals with limited treatment options in the realm of medical interventions and therapies. The disease showcases a…

Machine Learning · Computer Science 2024-07-12 Ritesh Mehta , Aleksandar Pramov , Shashank Verma

Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…

Other Quantitative Biology · Quantitative Biology 2025-10-20 Syed Ibad Hasnain

Autism Spectrum Disorder (ASD) is one neuro developmental disorder that is now widespread in the world. ASD persists throughout the life of an individual, impacting the way they behave and communicate, resulting to notable deficits…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Godfrin Ismail , Kenneth Chesoli , Golda Moni , Kinyua Gikunda

Medical events of interest, such as mortality, often happen at a low rate in electronic medical records, as most admitted patients survive. Training models with this imbalance rate (class density discrepancy) may lead to suboptimal…

Machine Learning · Computer Science 2022-08-02 Zepeng Huo , Xiaoning Qian , Shuai Huang , Zhangyang Wang , Bobak J. Mortazavi

Early prediction of Alzheimer's disease (AD) is crucial for timely intervention and treatment. This study aims to use machine learning approaches to analyze longitudinal electronic health records (EHRs) of patients with AD and identify…

Machine Learning · Computer Science 2025-04-29 Rumeng Li , Xun Wang , Dan Berlowitz , Brian Silver , Wen Hu , Heather Keating , Raelene Goodwin , Weisong Liu , Honghuang Lin , Hong Yu

Latent class analysis (LCA) is a useful tool to investigate the heterogeneity of a disease population with time-to-event data. We propose a new method based on non-parametric maximum likelihood estimator (NPMLE), which facilitates…

Methodology · Statistics 2022-02-03 Teng Fei , John Hanfelt , Limin Peng

Amyotrophic Lateral Sclerosis (ALS) constitutes a progressive neurodegenerative disease with varying symptoms, including decline in speech intelligibility. Existing studies, which recognize dysarthria in ALS patients by predicting the…

Machine Learning · Computer Science 2025-03-05 Loukas Ilias , Dimitris Askounis

Semi-supervised Anomaly Detection (AD) is a kind of data mining task which aims at learning features from partially-labeled datasets to help detect outliers. In this paper, we classify existing semi-supervised AD methods into two…

Machine Learning · Computer Science 2022-10-27 Chao Chen , Dawei Wang , Feng Mao , Zongzhang Zhang , Yang Yu

Automatic sleep staging is a challenging problem and state-of-the-art algorithms have not yet reached satisfactory performance to be used instead of manual scoring by a sleep technician. Much research has been done to find good feature…

Machine Learning · Computer Science 2018-05-15 Martin Längkvist , Amy Loutfi

An ensemble of classifiers combines several single classifiers to deliver a final prediction or classification decision. An increasingly provoking question is whether such systems can outperform the single best classifier. If so, what form…

Machine Learning · Computer Science 2022-09-07 Bhekisipho Twala , Eamon Molloy

Machine learning (ML) has advanced quickly, particularly throughout the area of health care. The diagnosis of neurodevelopment problems using ML is a very important area of healthcare. Autism spectrum disorder (ASD) is one of the…

Machine Learning · Computer Science 2024-04-04 Trapti Shrivastava , Harshal Chaudhari , Vrijendra Singh

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Lilia Lazli

Autism spectrum disorder (ASD) represents a neurodevelopmental condition characterized by difficulties in expressing emotions and communication, particularly during early childhood. Understanding the affective state of children at an early…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Aura Loredana Dan

Supporting student success requires collaboration among multiple stakeholders. Researchers have explored machine learning models for academic performance prediction; yet key challenges remain in ensuring these models are interpretable,…

Human-Computer Interaction · Computer Science 2025-05-12 Han Zhang , Yiyi Ren , Paula S. Nurius , Jennifer Mankoff , Anind K. Dey

Accurate diagnosis of Alzheimer's disease (AD) is both challenging and time consuming. With a systematic approach for early detection and diagnosis of AD, steps can be taken towards the treatment and prevention of the disease. This study…

Machine Learning · Computer Science 2022-12-12 Harshit Parmar , Eric Walden

Atrial fibrillation (AF) is the most common arrhythmia, increasing the risk of stroke, heart failure, and other cardiovascular complications. While AF detection algorithms perform well in identifying persistent AF, early-stage progression,…

Machine Learning · Computer Science 2025-08-28 Yongbin Lee , Ki H. Chon