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We intend to identify relationships between cancer cases and pollutant emissions and attempt to understand whether cancer in children is typically located together with some specific chemical combinations or is independent. Co-location…

The analysis of area-level aggregated summary data is common in many disciplines including epidemiology and the social sciences. Typically, Markov random field spatial models have been employed to acknowledge spatial dependence and allow…

Methodology · Statistics 2017-09-28 Katherine Wilson , Jon Wakefield

We develop a stochastic modeling approach based on spatial point processes of log-Gaussian Cox type for a collection of around 5000 landslide events provoked by a precipitation trigger in Sicily, Italy. Through the embedding into a…

Applications · Statistics 2017-08-11 Luigi Lombardo , Thomas Opitz , Raphael Huser

Many application domains such as ecology or genomics have to deal with multivariate non Gaussian observations. A typical example is the joint observation of the respective abundances of a set of species in a series of sites, aiming to…

Methodology · Statistics 2018-05-01 Julien Chiquet , Mahendra Mariadassou , Stéphane Robin

Estimating the marginal and joint densities of the long-term average intakes of different dietary components is an important problem in nutritional epidemiology. Since these variables cannot be directly measured, data are usually collected…

Methodology · Statistics 2022-05-18 Abhra Sarkar

Graphical models are ubiquitous tools to describe the interdependence between variables measured simultaneously such as large-scale gene or protein expression data. Gaussian graphical models (GGMs) are well-established tools for…

Methodology · Statistics 2020-01-09 Nilabja Guha , Veera Baladandayuthapani , Bani K. Mallick

Hierarchical models for regionally aggregated disease incidence data commonly involve region specific latent random effects that are modeled jointly as having a multivariate Gaussian distribution. The covariance or precision matrix…

Methodology · Statistics 2019-04-30 Abhirup Datta , Sudipto Banerjee , James S. Hodges

Determining the relevant spatial covariates is one of the most important problems in the analysis of point patterns. Parametric methods may lead to incorrect conclusions, especially when the model of interactions between points is wrong.…

Methodology · Statistics 2022-10-12 Jiří Dvořák , Tomáš Mrkvička

Air pollution is a major global health hazard, with fine particulate matter (PM10) linked to severe respiratory and cardiovascular diseases. Hence, analyzing and clustering spatio-temporal air quality data is crucial for understanding…

Methodology · Statistics 2025-06-02 Luca Aiello , Raffaele Argiento , Sirio Legramanti , Lucia Paci

Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput…

Machine Learning · Statistics 2018-09-19 Ioan Gabriel Bucur , Tom van Bussel , Tom Claassen , Tom Heskes

Mark-point dependence plays a critical role in research problems that can be fitted into the general framework of marked point processes. In this work, we focus on adjusting for mark-point dependence when estimating the mean and covariance…

Methodology · Statistics 2022-07-26 Ganggang Xu , Jingfei Zhang , Yehua Li , Yongtao Guan

Preferential sampling is a common feature in geostatistics and occurs when the locations to be sampled are chosen based on information about the phenomena under study. In this case, point pattern models are commonly used as the probability…

Methodology · Statistics 2022-10-27 Douglas Mateus da Silva , Dani Gamerman

We investigate spatial confounding in the presence of multivariate disease dependence. In the "analysis model perspective" of spatial confounding, adding a spatially dependent random effect can lead to significant variance inflation of the…

Methodology · Statistics 2026-02-13 Kyle Lin Wu , Sudipto Banerjee

Incorporating shape information is essential for the delineation of many organs and anatomical structures in medical images. While previous work has mainly focused on parametric spatial transformations applied on reference template shapes,…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Wang Zihao , Demarcy Thomas , Vandersteen Clair , Gnansia Dan , Raffaelli Charles , Guevara Nicolas , Delingette Hervé

A quality-Bayesian approach, combining the direct sampling method and the Bayesian inversion, is proposed to reconstruct the locations and intensities of the unknown acoustic sources using partial data. First, we extend the direct sampling…

Numerical Analysis · Mathematics 2020-04-10 Zhaoxing Li , Yanfang Liu , Jiguang Sun , Liwei Xu

Clustering is commonly performed as an initial analysis step for uncovering structure in 'omics datasets, e.g. to discover molecular subtypes of disease. The high-throughput, high-dimensional nature of these datasets means that they provide…

Methodology · Statistics 2023-03-02 Paul D. W. Kirk , Filippo Pagani , Sylvia Richardson

This paper proposes a Bayesian framework for localization of multiple sources in the event of accidental hazardous contaminant release. The framework assimilates sensor measurements of the contaminant concentration with an integrated…

Applications · Statistics 2018-10-18 Young-Jin Park , Piyush M. Tagade , Han-Lim Choi

We propose a spatio-temporal data-fusion framework for point data and gridded data with variables observed on different spatial supports. A latent Gaussian field with a Mat\'ern-SPDE prior provides a continuous space representation, while…

Methodology · Statistics 2025-11-19 Weiyue Zheng , Andrew Elliott , Claire Miller , Marian Scott

Recent advances in multiplex imaging have enabled researchers to locate different types of cells within a tissue sample. This is especially relevant for tumor immunology, as clinical regimes corresponding to different stages of disease or…

Maps of infectious disease---charting spatial variations in the force of infection, degree of endemicity, and the burden on human health---provide an essential evidence base to support planning towards global health targets. Contemporary…

Applications · Statistics 2017-09-21 Samir Bhatt , Ewan Cameron , Seth R Flaxman , Daniel J Weiss , David L Smith , Peter W Gething