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Suppose one is interested in estimating causal effects in the presence of potentially unmeasured confounding with the aid of a valid instrumental variable. This paper investigates the problem of making inferences about the average treatment…

Methodology · Statistics 2020-12-15 BaoLuo Sun , Wang Miao

Interpretability research often aims to predict how a model will respond to targeted interventions on specific mechanisms. However, it rarely predicts how a model will respond to unseen input data. This paper explores the promises and…

Machine Learning · Computer Science 2025-07-10 Victoria R. Li , Jenny Kaufmann , Martin Wattenberg , David Alvarez-Melis , Naomi Saphra

Understanding and inferencing Heterogeneous Treatment Effects (HTE) and Conditional Average Treatment Effects (CATE) are vital for developing personalized treatment recommendations. Many state-of-the-art approaches achieve inspiring…

Machine Learning · Computer Science 2024-08-28 Chan Hsu , Jun-Ting Wu , Yihuang Kang

Unmeasured confounding presents a common challenge in observational studies, potentially making standard causal parameters unidentifiable without additional assumptions. Given the increasing availability of diverse data sources, exploiting…

Methodology · Statistics 2023-09-18 Shanshan Luo , Yechi Zhang , Wei Li

A probabilistic expert system emulates the decision-making ability of a human expert through a directional graphical model. The first step in building such systems is to understand data generation mechanism. To this end, one may try to…

Methodology · Statistics 2021-09-29 Vahid Partovi Nia , Xinlin Li , Masoud Asgharian , Shoubo Hu , Zhitang Chen , Yanhui Geng

In evidence synthesis, effect modifiers are typically described as variables that induce treatment effect heterogeneity at the individual level, through treatment-covariate interactions in an outcome model parametrized at such level. As…

Methodology · Statistics 2026-05-07 Antonio Remiro-Azócar

While much of the causal inference literature has focused on addressing internal validity biases, both internal and external validity are necessary for unbiased estimates in a target population of interest. However, few generalizability…

Methodology · Statistics 2023-04-07 Irina Degtiar , Tim Layton , Jacob Wallace , Sherri Rose

The purpose of this work is to transport the information from multiple randomized controlled trials to the target population where we only have the control group data. Previous works rely critically on the mean exchangeability assumption.…

Machine Learning · Statistics 2023-09-29 Yuhang Zhang , Yue Liu , Zhihua Zhang

Interpretability research on large language models (LLMs) has yielded important insights into model behaviour, yet recurring pitfalls persist: findings that do not generalise, and causal interpretations that outrun the evidence. Our…

Machine Learning · Computer Science 2026-03-20 Shruti Joshi , Aaron Mueller , David Klindt , Wieland Brendel , Patrik Reizinger , Dhanya Sridhar

We establish the inferential properties of the mean-difference estimator for the average treatment effect in randomized experiments where each unit in a population is randomized to one of two treatments and then units within treatment…

Statistics Theory · Mathematics 2019-02-19 Zach Branson , Tirthankar Dasgupta

This article proposes a meta-learning method for estimating the conditional average treatment effect (CATE) from a few observational data. The proposed method learns how to estimate CATEs from multiple tasks and uses the knowledge for…

Machine Learning · Statistics 2023-05-22 Tomoharu Iwata , Yoichi Chikahara

This work considers the problem of transferring causal knowledge between tasks for Individual Treatment Effect (ITE) estimation. To this end, we theoretically assess the feasibility of transferring ITE knowledge and present a practical…

Machine Learning · Computer Science 2023-06-07 Ahmed Aloui , Juncheng Dong , Cat P. Le , Vahid Tarokh

This study focuses on exploring the use of local interpretability methods for explaining time series clustering models. Many of the state-of-the-art clustering models are not directly explainable. To provide explanations for these…

Machine Learning · Computer Science 2022-08-03 Ozan Ozyegen , Nicholas Prayogo , Mucahit Cevik , Ayse Basar

A data science task can be deemed as making sense of the data or testing a hypothesis about it. The conclusions inferred from data can greatly guide us to make informative decisions. Big data has enabled us to carry out countless prediction…

Machine Learning · Computer Science 2022-01-12 Wenhao Zhang , Ramin Ramezani , Arash Naeim

As language technologies gain prominence in real-world settings, it is important to understand how changes to language affect reader perceptions. This can be formalized as the causal effect of varying a linguistic attribute (e.g.,…

Computation and Language · Computer Science 2023-11-01 Victoria Lin , Louis-Philippe Morency , Eli Ben-Michael

Medical imaging models frequently fail when deployed across hospitals, scanners, populations, or imaging protocols due to domain shift, limiting their clinical reliability. While transfer learning and domain adaptation address such shifts…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Mohammed M. Abdelsamea , Daniel Tweneboah Anyimadu , Tasneem Selim , Saif Alzubi , Lei Zhang , Ahmed Karam Eldaly , Xujiong Ye

A common approach to mechanistic interpretability is to causally manipulate model representations via targeted interventions in order to understand what those representations encode. Here we ask whether such interventions create…

Machine Learning · Computer Science 2026-04-24 Satchel Grant , Simon Jerome Han , Alexa R. Tartaglini , Christopher Potts

We propose a machine-learning tool that yields causal inference on text in randomized trials. Based on a simple econometric framework in which text may capture outcomes of interest, our procedure addresses three questions: First, is the…

Econometrics · Economics 2025-03-04 Iman Modarressi , Jann Spiess , Amar Venugopal

Transporting causal information across populations is a critical challenge in clinical decision-making. Causal modeling provides criteria for identifiability and transportability, but these require knowledge of the causal graph, which…

Machine Learning · Statistics 2026-02-03 Konstantina Lelova , Gregory F. Cooper , Sofia Triantafillou

We systematically investigate issues due to mis-specification that arise in estimating causal effects when (treatment) interference is informed by a network available pre-intervention, i.e., in situations where the outcome of a unit may…

Methodology · Statistics 2018-10-22 Vishesh Karwa , Edoardo M. Airoldi