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Since the strong comorbid similarity in NDDs, such as attention-deficit hyperactivity disorder, can interfere with the accurate diagnosis of autism spectrum disorder (ASD), identifying unknown classes is extremely crucial and challenging…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Jiaming Yu , Zihao Guan , Xinyue Chang , Shujie Liu , Zhenshan Shi , Xiumei Liu , Changcai Yang , Riqing Chen , Lanyan Xue , Lifang Wei

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

We present an approach to model time series data from resting state fMRI for autism spectrum disorder (ASD) severity classification. We propose to adopt kernel machines and employ graph kernels that define a kernel dot product between two…

Machine Learning · Statistics 2016-12-04 Rushil Anirudh , Jayaraman J. Thiagarajan , Irene Kim , Wolfgang Polonik

Subjective cognitive decline (SCD) is a preclinical stage of Alzheimer's disease (AD) which occurs even before mild cognitive impairment (MCI). Progressive SCD will convert to MCI with the potential of further evolving to AD. Therefore,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Hao Guan , Ling Yue , Pew-Thian Yap , Shifu Xiao , Andrea Bozoki , Mingxia Liu

Effective and accurate diagnosis of Alzheimer's disease (AD) or mild cognitive impairment (MCI) can be critical for early treatment and thus has attracted more and more attention nowadays. Since first introduced, machine learning methods…

Computer Vision and Pattern Recognition · Computer Science 2014-04-29 Fayao Liu , Chunhua Shen

Saliency maps have been widely used to interpret deep learning classifiers for Alzheimer's disease (AD). However, since AD is heterogeneous and has multiple subtypes, the pathological mechanism of AD remains not fully understood and may…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Yihan Zhang , Xuanshuo Zhang , Wei Wu , Haohan Wang

Anomalous sound detection (ASD) is, nowadays, one of the topical subjects in machine listening discipline. Unsupervised detection is attracting a lot of interest due to its immediate applicability in many fields. For example, related to…

Audio and Speech Processing · Electrical Eng. & Systems 2020-06-30 Sergi Perez-Castanos , Javier Naranjo-Alcazar , Pedro Zuccarello , Maximo Cobos

BACKGROUND AND PURPOSE: Cerebral aneurysm is one of the most common cerebrovascular diseases, and SAH caused by its rupture has a very high mortality and disability rate. Existing automatic segmentation methods based on DLMs with TOF-MRA…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Meng Chen , Chen Geng , Dongdong Wang , Jiajun Zhang , Ruoyu Di , Fengmei Li , Zhiyong Zhou , Sirong Piao , Yuxin Li , Yaikang Dai

Alzheimer's disease (AD) is the most common type of dementia accompanied with brain atrophy. Structural measurements of brain atrophy in specific brain structures such as hippocampus using magnetic resonance imaging (MRI) have been reported…

Medical Physics · Physics 2016-05-10 Kenya Murase , Naohiko Gondo , Tsutomu Soma

Anomaly detection in medical imaging is essential for identifying rare pathological conditions, particularly when annotated abnormal samples are limited. We propose a hybrid anomaly detection framework that integrates self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Pritam Kar , Gouri Lakshmi S , Saptarshi Bej

Resting-state functional Magnetic Resonance Imaging (R-fMRI) holds the promise to reveal functional biomarkers of neuropsychiatric disorders. However, extracting such biomarkers is challenging for complex multi-faceted neuropatholo-gies,…

Deep learning models for MRI classification face two recurring problems: they are typically limited by low sample size, and are abstracted by their own complexity (the "black box problem"). In this paper, we train a convolutional neural…

Quantitative Methods · Quantitative Biology 2020-05-28 Matthew Leming , Juan Manuel Górriz , John Suckling

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Autism spectrum disorder (ASD) is characterized by significant challenges in social interaction and comprehending communication signals. Recently, therapeutic interventions for ASD have increasingly utilized Deep learning powered-computer…

Computer Vision and Pattern Recognition · Computer Science 2024-08-30 Pavan Uttej Ravva , Behdokht Kiafar , Pinar Kullu , Jicheng Li , Anjana Bhat , Roghayeh Leila Barmaki

This paper has been withdrawn by the authors due to insufficient or definition error(s) in the ethics approval protocol. Autism spectrum disorders (ASD) impact the cognitive, social, communicative and behavioral abilities of an individual.…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Andrew Cook , Bappaditya Mandal , Donna Berry , Matthew Johnson

Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor problems for people with a detrimental effect on the functioning of the nervous system. In order to diagnose MS, multiple screening methods have been…

Detection of Alzheimer's Disease (AD) from neuroimaging data such as MRI through machine learning have been a subject of intense research in recent years. Recent success of deep learning in computer vision have progressed such research…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Marcia Hon , Naimul Khan

Unsupervised anomaly detection in brain imaging is challenging. In this paper, we propose self-supervised masked mesh learning for unsupervised anomaly detection on 3D cortical surfaces. Our framework leverages the intrinsic geometry of the…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 Hao-Chun Yang , Sicheng Dai , Saige Rutherford , Christian Gaser , Andre F Marquand , Christian F Beckmann , Thomas Wolfers

The detection of heterogeneous mental disorders based on brain readouts remains challenging due to the complexity of symptoms and the absence of reliable biomarkers. This paper introduces CAM (Cortical Anomaly Detection through Masked Image…

Image and Video Processing · Electrical Eng. & Systems 2024-02-14 Hao-Chun Yang , Ole Andreassen , Lars Tjelta Westlye , Andre F. Marquand , Christian F. Beckmann , Thomas Wolfers

The objective of this study is to develop a deep-learning based detection and diagnosis technique for carotid atherosclerosis using a portable freehand 3D ultrasound (US) imaging system. A total of 127 3D carotid artery scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2023-11-10 Jiawen Li , Yunqian Huang , Sheng Song , Hongbo Chen , Junni Shi , Duo Xu , Haibin Zhang , Man Chen , Rui Zheng