Related papers: Feature Selection for Data Integration with Mixed …
It is common to show the confidence intervals or $p$-values of selected features, or predictor variables in regression, but they often involve selection bias. The selective inference approach solves this bias by conditioning on the…
Iterative method selection is crucial for solving sparse linear systems because these methods inherently lack robustness. Though image-based selection approaches have shown promise, their feature extraction techniques might encode distinct…
Cancer has relational information residing at varying scales, modalities, and resolutions of the acquired data, such as radiology, pathology, genomics, proteomics, and clinical records. Integrating diverse data types can improve the…
The analysis of large collections of image data is still a challenging problem due to the difficulty of capturing the true concepts in visual data. The similarity between images could be computed using different and possibly multimodal…
In big data analysis, a simple task such as linear regression can become very challenging as the variable dimension $p$ grows. As a result, variable screening is inevitable in many scientific studies. In recent years, randomized algorithms…
Penalized selection criteria like AIC or BIC are among the most popular methods for variable selection. Their theoretical properties have been studied intensively and are well understood, but making use of them in case of high-dimensional…
Machine learning methods are used to discover complex nonlinear relationships in biological and medical data. However, sophisticated learning models are computationally unfeasible for data with millions of features. Here we introduce the…
Gallstone disease is a complex, multifactorial condition with significant global health burdens. Identifying underlying risk factors and their interactions is crucial for early diagnosis, targeted prevention, and effective clinical…
Breast cancer is the most common invasive cancer in women. Besides the primary B-mode ultrasound screening, sonographers have explored the inclusion of Doppler, strain and shear-wave elasticity imaging to advance the diagnosis. However,…
In modern randomized experiments, large-scale data collection increasingly yields rich baseline covariates and auxiliary information from multiple sources. Such information offers opportunities for more precise treatment effect estimation,…
This article describes a full Bayesian treatment for simultaneous fixed-effect selection and parameter estimation in high-dimensional generalized linear mixed models. The approach consists of using a Bayesian adaptive Lasso penalty for…
Breast cancer is a significant health concern affecting millions of women worldwide. Accurate survival risk stratification plays a crucial role in guiding personalised treatment decisions and improving patient outcomes. Here we present…
Omic data are characterized by the presence of strong dependence structures that result either from data acquisition or from some underlying biological processes. In metabolomics, for instance, data resulting from Liquid Chromatography-Mass…
Many modern datasets consist of multiple related matrices measured on a common set of units, where the goal is to recover the shared low-dimensional subspace. While the Angle-based Joint and Individual Variation Explained (AJIVE) framework…
Radiogenomics is an emerging field in cancer research that combines medical imaging data with genomic data to predict patients clinical outcomes. In this paper, we propose a multivariate sparse group lasso joint model to integrate imaging…
Multiple imputation is widely used for handling missing data in real-world applications. For variable selection on multiply-imputed datasets, however, if selection is performed on each imputed dataset separately, it can result in different…
The essence of precision oncology lies in its commitment to tailor targeted treatments and care measures to each patient based on the individual characteristics of the tumor. The inherent heterogeneity of tumors necessitates gathering…
We consider the analysis of high dimensional data given in the form of a matrix with columns consisting of observations and rows consisting of features. Often the data is such that the observations do not reside on a regular grid, and the…
Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…
In the last decade, embedded multi-label feature selection methods, incorporating the search for feature subsets into model optimization, have attracted considerable attention in accurately evaluating the importance of features in…