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Stepped wedge cluster randomized trials (SW-CRTs) have become increasingly popular and are used for a variety of interventions and outcomes, often chosen for their feasibility advantages. SW-CRTs must account for time trends in the outcome…

Methodology · Statistics 2024-07-16 Lee Kennedy-Shaffer , Victor De Gruttola , Marc Lipsitch

Researchers often turn to block randomization to increase the precision of their inference or due to practical considerations, such as in multisite trials. However, if the number of treatments under consideration is large it might not be…

Methodology · Statistics 2025-08-26 Taehyeon Koo , Nicole E. Pashley

This paper presents and analyzes an approach to cluster-based inference for dependent data. The primary setting considered here is with spatially indexed data in which the dependence structure of observed random variables is characterized…

Statistics Theory · Mathematics 2022-11-16 Jianfei Cao , Christian Hansen , Damian Kozbur , Lucciano Villacorta

To generalize inferences from a randomized trial to the target population of all trial-eligible individuals, investigators can use nested trial designs, where the randomized individuals are nested within a cohort of trial-eligible…

Linear mixed-effects models are widely used in analyzing clustered or repeated measures data. We propose a quasi-likelihood approach for estimation and inference of the unknown parameters in linear mixed-effects models with high-dimensional…

Methodology · Statistics 2021-03-10 Sai Li , Tony T. Cai , Hongzhe Li

We provide finite-sample distribution approximations, that are uniform in the parameter, for inference in linear mixed models. Focus is on variances and covariances of random effects in cases where existing theory fails because their…

Statistics Theory · Mathematics 2025-07-29 Karl Oskar Ekvall , Matteo Bottai

In mixture modeling and clustering applications, the number of components and clusters is often not known. A stick-breaking mixture model, such as the Dirichlet process mixture model, is an appealing construction that assumes infinitely…

Methodology · Statistics 2024-03-05 Cheng Zeng , Jeffrey W. Miller , Leo L. Duan

Linear regression models depend directly on the design matrix and its properties. Techniques that efficiently estimate model coefficients by partitioning rows of the design matrix are increasingly popular for large-scale problems because…

Machine Learning · Statistics 2019-07-23 Michael J. Kane , Bryan Lewis , Sekhar Tatikonda , Simon Urbanek

This study considers various semiparametric difference-in-differences models under different assumptions on the relation between the treatment group identifier, time and covariates for cross-sectional and panel data. The variance lower…

Econometrics · Economics 2020-08-17 Michael Zimmert

The clustering of bounded data presents unique challenges in statistical analysis due to the constraints imposed on the data values. This paper introduces a novel method for model-based clustering specifically designed for bounded data.…

Methodology · Statistics 2025-05-16 Luca Scrucca

When conducting a paired $2\times2$ crossover design, each subject is paired with another subject with similar characteristics. The pair is then randomized to the same sequence of two treatments. That is, the two subjects receive the first…

Statistics Theory · Mathematics 2008-12-18 Laura J. Simon , Vernon M. Chinchilli

Likelihood methods for measuring statistical evidence obey the likelihood principle while maintaining bounded and well-controlled frequency properties. These methods lend themselves to sequential study designs because they measure the…

Methodology · Statistics 2017-11-07 Jeffrey D Blume , Leena Choi

The mixture models have become widely used in clustering, given its probabilistic framework in which its based, however, for modern databases that are characterized by their large size, these models behave disappointingly in setting out the…

Machine Learning · Statistics 2017-02-01 Abdelghafour Talibi , Boujemâa Achchab , Rafik Lasri

Evaluating blocked randomized experiments from a potential outcomes perspective has two primary branches of work. The first focuses on larger blocks, with multiple treatment and control units in each block. The second focuses on matched…

Methodology · Statistics 2024-05-31 Nicole E. Pashley , Luke W. Miratrix

We consider a potential outcomes model in which interference may be present between any two units but the extent of interference diminishes with spatial distance. The causal estimand is the global average treatment effect, which compares…

Methodology · Statistics 2022-09-16 Michael P. Leung

Reproducible research in Machine Learning has seen a salutary abundance of progress lately: workflows, transparency, and statistical analysis of validation and test performance. We build on these efforts and take them further. We offer a…

A mixture of multivariate contaminated normal (MCN) distributions is a useful model-based clustering technique to accommodate data sets with mild outliers. However, this model only works when fitted to complete data sets, which is often not…

Methodology · Statistics 2020-12-11 Hung Tong , Cristina Tortora

Recent deep clustering models have produced impressive clustering performance. However, a common issue with existing methods is the disparity between global and local feature structures. While local structures typically show strong…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Hanyang Li , Yuheng Jia , Hui Liu , Junhui Hou

The problem of missing data has been persistent for a long time and poses a major obstacle in machine learning and statistical data analysis. Past works in this field have tried using various data imputation techniques to fill in the…

Machine Learning · Computer Science 2020-11-20 Rishab Khincha , Utkarsh Sarawgi , Wazeer Zulfikar , Pattie Maes

Hierarchical probabilistic models, such as mixture models, are used for cluster analysis. These models have two types of variables: observable and latent. In cluster analysis, the latent variable is estimated, and it is expected that…

Machine Learning · Statistics 2017-06-26 Keisuke Yamazaki