Related papers: Permutation patterns in genome rearrangement probl…
Genome rearrangements are events in which large blocks of DNA exchange pieces during evolution. The analysis of such events is a tool for understanding evolutionary genomics, based on finding the minimum number of rearrangements to…
An occurrence of a classical pattern p in a permutation \pi is a subsequence of \pi whose letters are in the same relative order (of size) as those in p. In an occurrence of a generalized pattern, some letters of that subsequence may be…
The Genome Median Problem is an important problem in phylogenetic reconstruction under rearrangement models. It can be stated as follows: given three genomes, find a fourth that minimizes the sum of the pairwise rearrangement distances…
Much of contemporary systems biology owes its success to the abstraction of a network, the idea that diverse kinds of molecular, cellular, and organismal species and interactions can be modeled as relational nodes and edges in a graph of…
We enumerate permutations that avoid all but one of the $k$ patterns of length $k$ starting with a monotone increasing subsequence of length $k-1$. We compare the size of such permutation classes to the size of the class of permutations…
Genome rearrangements can be modeled as $k$-breaks, which break a genome at k positions and glue the resulting fragments in a new order. In particular, reversals, translocations, fusions, and fissions are modeled as $2$-breaks, and…
In this paper, we are interested in the combinatorial analysis of the whole genome duplication - random loss model of genome rearrangement initiated in a paper of Chaudhuri, Chen, Mihaescu, and Rao in SODA 2006 and continued by Bouvel and…
Genome rearrangement is a common model for molecular evolution. In this paper, we consider the Pairwise Rearrangement problem, which takes as input two genomes and asks for the number of minimum-length sequences of permissible operations…
We survey permutation-based methods for approximate k-nearest neighbor search. In these methods, every data point is represented by a ranked list of pivots sorted by the distance to this point. Such ranked lists are called permutations. The…
In Soda'06, Chaudhuri, Chen, Mihaescu and Rao study algorithmic properties of the tandem duplication - random loss model of genome rearrangement, well-known in evolutionary biology. In their model, the cost of one step of duplication-loss…
The classical rearrangement inequality provides bounds for the sum of products of two sequences under permutations of terms and show that similarly ordered sequences provide the largest value whereas opposite ordered sequences provide the…
Comtet introduced the notion of indecomposable permutations in 1972. A permutation is indecomposable if and only if it has no proper prefix which is itself a permutation. Indecomposable permutations were studied in the literature in various…
We consider permutation classes having two basis elements of size three and one further basis element. We completely classify the possible enumeration sequences of such classes and demonstrate that there are far fewer of them than might be…
Recent advances in high-throughput genomics technologies have resulted in the sequencing of large numbers of (near) complete genomes. These genome sequences are being mined for important functional elements, such as genes. They are also…
In the last years, different types of patterns in permutations have been studied: vincular, bivincular and mesh patterns, just to name a few. Every type of permutation pattern naturally defines a corresponding computational problem: Given a…
A sample of n generic points in the xy-plane defines a permutation that relates their ranks along the two axes. Every subset of k points similarly defines a pattern, which occurs in that permutation. The number of occurrences of small…
Two genomes over the same set of gene families form a canonical pair when each of them has exactly one gene from each family. Different distances of canonical genomes can be derived from a structure called breakpoint graph, which represents…
We review a recent trend in computational systems biology which aims at using pattern recognition algorithms to infer the structure of large-scale biological networks from heterogeneous genomic data. We present several strategies that have…
We explore various techniques to compress a permutation $\pi$ over n integers, taking advantage of ordered subsequences in $\pi$, while supporting its application $\pi$(i) and the application of its inverse $\pi^{-1}(i)$ in small time. Our…
Some genes can change their relative locations in a genome. Thus for different individuals of the same species, the orders of genes might be different. Such jumping genes are called transposons. A practical problem is to determine…