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We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

Populations and Evolution · Quantitative Biology 2018-07-19 George W. A. Constable , Alan J. McKane

This is an introductory review of deterministic mutation-selection models for asexual populations (i.e., quasispecies theory) and related topics. First, the basic concepts of fitness, mutations, and sequence space are introduced. Different…

Populations and Evolution · Quantitative Biology 2007-07-26 Kavita Jain , Joachim Krug

Nonlocal aggregation-diffusion models, when coupled with a spatial map, can capture cognitive and memory-based influences on animal movement and population-level patterns. In this work, we study a one-dimensional…

Analysis of PDEs · Mathematics 2025-03-17 Yurij Salmaniw , Di Liu , Junping Shi , Hao Wang

Collective motion is an ubiquitous phenomenon in nature, inspiring engineers, physicists and mathematicians to develop mathematical models and bio-inspired designs. Collective motion at small to medium group sizes ($\sim$10-1000…

Machine Learning · Computer Science 2024-01-19 Utkarsh Pratiush , Arshed Nabeel , Vishwesha Guttal , Prathosh AP

In this paper the spatial-temporal dynamics of the members of interacting populations is described by nonlinear partial differential equations. We consider the migration as a diffusion process influenced by the changing values of the birth…

Exactly Solvable and Integrable Systems · Physics 2012-08-28 Ivan jordanov , Nikolay K. Vitanov , Elena Nikolova

The effect of demographic stochasticity, in the form of Gaussian white noise, in a predator-prey model with one fast and two slow variables is studied. We derive the stochastic differential equations (SDEs) from a discrete model. For…

Dynamical Systems · Mathematics 2018-12-24 Susmita Sadhu , Christian Kuehn

We study the interplay of population growth and evolutionary dynamics using a stochastic model based on birth and death events. In contrast to the common assumption of an independent population size, evolution can be strongly affected by…

Populations and Evolution · Quantitative Biology 2012-06-05 Jonas Cremer , Anna Melbinger , Erwin Frey

We develop a continuous mathematical model of population dynamics that describes the sequential emergence of new genotypes under limited resources. The framework models genotype density as a nonlinear flow in mutation space, combining…

Populations and Evolution · Quantitative Biology 2025-12-10 Alexander Bratus , Tatiana Yakushkina , Vladimir Posvyanski

This work proposes stochastic partial differential equations (SPDEs) as a practical tool to replicate clustering effects of more detailed particle-based dynamics. Inspired by membrane-mediated receptor dynamics on cell surfaces, we…

Quantitative Methods · Quantitative Biology 2025-01-22 Nathalie Wehlitz , Mohsen Sadeghi , Alberto Montefusco , Christof Schütte , Grigorios A. Pavliotis , Stefanie Winkelmann

The literature considers multi-type Markov branching processes (BPs), where the offspring distribution depends only on the living (current) population. We analyse the total-current population-dependent BPs where the offspring distribution…

Probability · Mathematics 2024-06-14 Khushboo Agarwal

Models of population growth and extinction are an increasingly popular subject of study. However, consequences of stochasticity and noise in shaping distributions and outcomes are not sufficiently explored. Here we consider a distributed…

Statistical Mechanics · Physics 2020-11-11 Bertrand Ottino-Löffler , Mehran Kardar

We are interested in the dynamics of a population structured by a phenotypic trait. Individuals reproduce sexually, which is represented by a non-linear integral operator. This operator is combined to a multiplicative operator representing…

Analysis of PDEs · Mathematics 2021-04-14 Gaël Raoul

Deterministic continuum models formulated in terms of non-local partial differential equations for the evolutionary dynamics of populations structured by phenotypic traits have been used recently to address open questions concerning the…

Populations and Evolution · Quantitative Biology 2020-10-14 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

We present an algorithm for the stochastic simulation of gene expression and heterogeneous population dynamics. The algorithm combines an exact method to simulate molecular-level fluctuations in single cells and a constant-number Monte…

Computational Physics · Physics 2016-08-24 Daniel A. Charlebois , Jukka Intosalmi , Dawn Fraser , Mads Kaern

We consider a stochastic individual-based model of adaptive dynamics for an asexually reproducing population with mutation, with linear birth and death rates, as well as a density-dependent competition. To depict repeating changes of the…

Populations and Evolution · Quantitative Biology 2025-05-28 Manuel Esser , Anna Kraut

Predicting the adaptation of populations to a changing environment is crucial to assess the impact of human activities on biodiversity. Many theoretical studies have tackled this issue by modeling the evolution of quantitative traits…

Analysis of PDEs · Mathematics 2022-06-28 Jimmy Garnier , O Cotto , T Bourgeron , E Bouin , T Lepoutre , O Ronce , V Calvez

A class of models of biological population and communities with a singular equilibrium at the origin is analyzed; it is shown that these models can possess a dynamical regime of deterministic extinction, which is crucially important from…

Quantitative Methods · Quantitative Biology 2007-05-23 Faina S Berezovskaya , Artem S Novozhilov , Georgy P Karev

We consider a nonlinear coupled discrete-time model of population dynamics. This model describes the movement of populations within a heterogeneous landscape, where the growth of subpopulations are modelled by (possibly different) bounded…

Dynamical Systems · Mathematics 2024-05-08 Blake McGrane-Corrigan , Oliver Mason , Rafael de Andrade Moral

We introduce and analyze several aspects of a new model for cell differentiation. It assumes that differentiation of progenitor cells is a continuous process. From the mathematical point of view, it is based on partial differential…

Analysis of PDEs · Mathematics 2013-01-21 Marie Doumic , Anna Marciniak-Czochra , Benoit Perthame , Jorge P. Zubelli

A Markovian model of group-structured (two-level) population dynamics features births, deaths, and migrations of individuals, and fission and extinction of groups. These models are useful for studying group selection and other evolutionary…

Probability · Mathematics 2019-02-26 A. Puhalskii , B. Simon
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