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Functional Magnetic Resonance Imaging (fMRI) has transformed our understanding of brain function in-vivo. However, the neurovascular coupling mechanisms underlying fMRI are somewhat "distant" from neural activity. Interestingly, evidence…

Medical Physics · Physics 2020-01-29 Daniel Nunes , Rita Gil , Noam Shemesh

Diffusion functional MRI (dfMRI) is a promising technique to map functional activations by acquiring diffusion-weighed spin-echo images. In previous studies, dfMRI showed higher spatial accuracy at activation mapping compared to classic…

Medical Physics · Physics 2019-08-15 Alberto De Luca , Lara Schlaffke , Jeroen CW Siero , Martijn Froeling , Alexander Leemans

Functional Magnetic Resonance Imaging (fMRI) is predominantly harnessed for spatially mapping activation foci along distributed pathways. However, resolving dynamic information on activation sequence remains elusive. Here, we show an…

Medical Physics · Physics 2020-02-04 Rita Gil , Francisca F. Fernandes , Noam Shemesh

Brain activation mapping using functional MRI (fMRI) based on blood oxygenation level-dependent (BOLD) contrast has been conventionally focused on probing gray matter, the BOLD contrast in white matter having been generally disregarded.…

Signal Processing · Electrical Eng. & Systems 2019-10-25 David Abramian , Martin Larsson , Anders Eklund , Hamid Behjat

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial method for white matter (WM) parcellation to enable analysis of brains structural connectivity in health and disease. Current fiber clustering strategies primarily use…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Bocheng Guo , Jin Wang , Yijie Li , Junyi Wang , Mingyu Gao , Puming Feng , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

Functional magnetic resonance imaging (fMRI) is one of the most popular methods for studying the human brain. Task-related fMRI data processing aims to determine which brain areas are activated when a specific task is performed and is…

Signal Processing · Electrical Eng. & Systems 2022-10-18 Paris A. Karakasis , Athanasios P. Liavas , Nicholas D. Sidiropoulos , Panagiotis G. Simos , Efrosini Papadaki

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

Applications · Statistics 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

Finding an appropriate representation of dynamic activities in the brain is crucial for many downstream applications. Due to its highly dynamic nature, temporally averaged fMRI (functional magnetic resonance imaging) can only provide a…

Machine Learning · Computer Science 2022-08-18 Sikun Lin , Shuyun Tang , Scott Grafton , Ambuj Singh

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Accurate identification of brain function is necessary to understand the neurobiology of cognitive ageing, and thereby promote well-being across the lifespan. A common tool used to investigate neurocognitive ageing is functional magnetic…

Neurons and Cognition · Quantitative Biology 2020-05-21 Kamen A. Tsvetanov , Richard N. A. Henson , James B. Rowe

Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used to visualize brain activation regions by detecting hemodynamic responses associated with increased metabolic demand. While alternative MRI…

Quantitative Methods · Quantitative Biology 2024-09-13 Kyu-Jin Jung , Chuanjiang Cui , Soo-Hyung Lee , Chan-Hee Park , Ji-Won Chun , Dong-Hyun Kim

An unprecedented amount of existing functional Magnetic Resonance Imaging (fMRI) data provides a new opportunity to understand the relationship between functional fluctuation and human cognition/behavior using a data-driven approach. To…

Machine Learning · Computer Science 2024-09-18 Jiaqi Ding , Tingting Dan , Ziquan Wei , Hyuna Cho , Paul J. Laurienti , Won Hwa Kim , Guorong Wu

The auditory pathway is widely distributed throughout the brain, and is perhaps one of the most interesting networks in the context of neuroplasticity. Accurate mapping of neural activity in the entire pathway, preferably noninvasively, and…

Medical Physics · Physics 2019-03-21 Guilherme Blazquez Freches , Cristina Chavarrias , Noam Shemesh

Localizing neuronal activity in the brain, both in time and in space, is a central challenge to advance the understanding of brain function. Because of the inability of any single neuroimaging techniques to cover all aspects at once, there…

Neurons and Cognition · Quantitative Biology 2013-07-09 Yaroslav O. Halchenko , Michael Hanke , James V. Haxby , Stephen Jose Hanson , Christoph S. Herrmann

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

This study proposes an approach to estimate the functional localization and connectivity from CBF and BOLD signals simultaneously measured by ASL (arterial spin labeling) MRI, especially using exploratory Structural Equation Modeling…

Neurons and Cognition · Quantitative Biology 2017-04-11 Jiancheng Zhuang

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Resting-state functional magnetic resonance imaging (rs-fMRI), which measures the spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, is increasingly utilized for the investigation of the brain's physiological and…

Functional MRI (fMRI) is widely used to examine brain functionality by detecting alteration in oxygenated blood flow that arises with brain activity. In this study, complexity specific image categorization across different visual datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Vamshi K. Kancharala , Debanjali Bhattacharya , Neelam Sinha

Understanding human fetal neurodevelopment is of great clinical importance as abnormal development is linked to adverse neuropsychiatric outcomes after birth. Recent advances in functional Magnetic Resonance Imaging (fMRI) have provided new…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Xiangrui Li , Jasmine Hect , Moriah Thomason , Dongxiao Zhu
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