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Digital pathology enables remote access or consults and powerful image analysis algorithms. However, the slide digitization process can create artifacts such as out-of-focus (OOF). OOF is often only detected upon careful review, potentially…

Computer Vision and Pattern Recognition · Computer Science 2020-06-03 Timo Kohlberger , Yun Liu , Melissa Moran , Po-Hsuan , Chen , Trissia Brown , Craig H. Mermel , Jason D. Hipp , Martin C. Stumpe

Colonoscopy is used for colorectal cancer (CRC) screening. Extracting details of the colonoscopy findings from free text in electronic health records (EHRs) can be used to determine patient risk for CRC and colorectal screening strategies.…

Computation and Language · Computer Science 2021-08-26 Shashank Reddy Vadyala , Eric A. Sherer

Purpose-Optimal use of established and imaging methods, such as multiparametric magnetic resonance imaging(mpMRI) can simultaneously identify key functional parameters and provide unique imaging phenotypes of breast cancer. Therefore, we…

Artificial Intelligence (AI) has demonstrated success in computational pathology (CPath) for disease detection, biomarker classification, and prognosis prediction. However, its potential to learn unintended demographic biases, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Shengjia Chen , Ruchika Verma , Kevin Clare , Jannes Jegminat , Eugenia Alleva , Kuan-lin Huang , Brandon Veremis , Thomas Fuchs , Gabriele Campanella

Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…

Time-to-event prediction, e.g. cancer survival analysis or hospital length of stay, is a highly prominent machine learning task in medical and healthcare applications. However, only a few interpretable machine learning methods comply with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Hubert Baniecki , Bartlomiej Sobieski , Patryk Szatkowski , Przemyslaw Bombinski , Przemyslaw Biecek

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

Artificial Intelligence · Computer Science 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Pathology image segmentation is crucial in computational pathology for analyzing histological features relevant to cancer diagnosis and prognosis. However, current methods face major challenges in clinical applications due to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zhixuan Chen , Junlin Hou , Liqi Lin , Yihui Wang , Yequan Bie , Xi Wang , Yanning Zhou , Ronald Cheong Kin Chan , Hao Chen

Over the past decades, statisticians and machine-learning researchers have developed literally thousands of new tools for the reduction of high-dimensional data in order to identify the variables most responsible for a particular trait.…

Machine Learning · Statistics 2012-05-31 Chamont Wang , Jana Gevertz , Chaur-Chin Chen , Leonardo Auslender

Digital pathology is not only one of the most promising fields of diagnostic medicine, but at the same time a hot topic for fundamental research. Digital pathology is not just the transfer of histopathological slides into digital…

Artificial Intelligence · Computer Science 2017-12-20 Andreas Holzinger , Bernd Malle , Peter Kieseberg , Peter M. Roth , Heimo Müller , Robert Reihs , Kurt Zatloukal

Automatic radiology report generation has been an attracting research problem towards computer-aided diagnosis to alleviate the workload of doctors in recent years. Deep learning techniques for natural image captioning are successfully…

Computer Vision and Pattern Recognition · Computer Science 2020-02-20 Yixiao Zhang , Xiaosong Wang , Ziyue Xu , Qihang Yu , Alan Yuille , Daguang Xu

Large language models (LLMs) are effective at capturing complex, valuable conceptual representations from textual data for a wide range of real-world applications. However, in fields like Intelligent Fault Diagnosis (IFD), incorporating…

Artificial Intelligence · Computer Science 2024-12-03 Hamzah A. A. M. Qaid , Bo Zhang , Dan Li , See-Kiong Ng , Wei Li

Vision language models (VLM) have achieved success in both natural language comprehension and image recognition tasks. However, their use in pathology report generation for whole slide images (WSIs) is still limited due to the huge size of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Jing Wei Tan , SeungKyu Kim , Eunsu Kim , Sung Hak Lee , Sangjeong Ahn , Won-Ki Jeong

Classification is one of the core problems in Computer-Aided Diagnosis (CAD), targeting for early cancer detection using 3D medical imaging interpretation. High detection sensitivity with desirably low false positive (FP) rate is critical…

Computer Vision and Pattern Recognition · Computer Science 2014-05-20 Meizhu Liu , Le Lu , Xiaojing Ye , Shipeng Yu

The complexity of human cancer often results in significant heterogeneity in response to treatment. Precision medicine offers potential to improve patient outcomes by leveraging this heterogeneity. Individualized treatment rules (ITRs)…

Obtaining datasets labeled to facilitate model development is a challenge for most machine learning tasks. The difficulty is heightened for medical imaging, where data itself is limited in accessibility and labeling requires costly time and…

Computation and Language · Computer Science 2018-10-03 Nithya Attaluri , Ahmed Nasir , Carolynne Powe , Harold Racz , Ben Covington , Li Yao , Jordan Prosky , Eric Poblenz , Tobi Olatunji , Kevin Lyman

The aggressiveness of prostate cancer, the most common cancer in men worldwide, is primarily assessed based on histopathological data using the Gleason scoring system. While artificial intelligence (AI) has shown promise in accurately…

Background: Tumour budding is an independent predictor of metastasis and prognosis in colorectal cancer and is a vital part of the pathology specification report. In a conventional pathological section observation process, pathologists have…

Medical Physics · Physics 2025-03-21 Yiyan Su , Ruiqing Sun , Yajing Wang , Yanfeng xi , Shaohui Zhang

In histopathology, human experts primarily rely on color as a means of enhancing contrast to interpret tissue morphology, whereas machine vision models process color as raw statistical information. This distinction raises a fundamental…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Farnaz Kheiri , Shahryar Rahnamayan , Masoud Makrehchi