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Timely cancer reporting data are required in order to understand the impact of cancer, inform public health resource planning and implement cancer policy especially in Sub Saharan Africa where the reporting lag is behind world averages.…

Machine Learning · Computer Science 2020-09-02 Waheeda Saib , Tapiwa Chiwewe , Elvira Singh

Like most global cancer registries, the National Cancer Registry in South Africa employs expert human coders to label pathology reports using appropriate International Classification of Disease for Oncology (ICD-O) codes spanning 42…

Machine Learning · Computer Science 2020-08-31 Waheeda Saib , David Sengeh , Gcininwe Dlamini , Elvira Singh

Importance Incidental thyroid findings (ITFs) are increasingly detected on imaging performed for non-thyroid indications. Their prevalence, features, and clinical consequences remain undefined. Objective To develop, validate, and deploy a…

We report about the application of state-of-the-art deep learning techniques to the automatic and interpretable assignment of ICD-O3 topography and morphology codes to free-text cancer reports. We present results on a large dataset (more…

Machine Learning · Computer Science 2021-01-12 Stefano Martina , Leonardo Ventura , Paolo Frasconi

Artificial intelligence (AI) holds strong potential for medical diagnostics, yet its clinical adoption is limited by a lack of interpretability and generalizability. This study introduces the Pathobiological Dictionary for Liver Cancer…

Recent advances in genomic sequencing technology have resulted in an abundance of genome sequence data. Despite the progress in interpreting those data, there remains a broad scope for their translation into clinical and societal benefits.…

Genomics · Quantitative Biology 2021-12-13 Abhinav Jain , Greg Slabaugh , Deepti Gurdasani

Automatic objective non-invasive detection of pathological voice based on computerized analysis of acoustic signals can play an important role in early diagnosis, progression tracking and even effective treatment of pathological voices. In…

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

Clinical notes contain unstructured text provided by clinicians during patient encounters. These notes are usually accompanied by a sequence of diagnostic codes following the International Classification of Diseases (ICD). Correctly…

Machine Learning · Computer Science 2025-10-17 Mohammad Mansoori , Amira Soliman , Farzaneh Etminani

Artificial intelligence may assist healthcare systems in meeting increasing demand for pathology services while maintaining diagnostic quality and reducing turnaround time and costs. We aimed to investigate the performance of an…

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Large Language Models (LLMs) have shown significant promise across various natural language processing tasks. However, their application in the field of pathology, particularly for extracting meaningful insights from unstructured medical…

Computation and Language · Computer Science 2025-03-04 Rachit Saluja , Jacob Rosenthal , Yoav Artzi , David J. Pisapia , Benjamin L. Liechty , Mert R. Sabuncu

Pathological images play an essential role in cancer prognosis, while survival analysis, which integrates computational techniques, can predict critical clinical events such as patient mortality or disease recurrence from whole-slide images…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Guo Tang , Songhan Jiang , Jinpeng Lu , Linghan Cai , Yongbing Zhang

Cancer is the second leading cause of death in the world. Diagnosing cancer early on can save many lives. Pathologists have to look at tissue microarray (TMA) images manually to identify tumors, which can be time-consuming, inconsistent and…

Machine Learning · Computer Science 2024-09-04 Iris Yan

The histological assessment of human tissue has emerged as the key challenge for detection and treatment of cancer. A plethora of different data sources ranging from tissue microarray data to gene expression, proteomics or metabolomics data…

Computer Vision and Pattern Recognition · Computer Science 2016-01-05 Thomas J. Fuchs , Joachim M. Buhmann

Patient-reported outcomes (PROs) directly collected from cancer patients being treated with radiation therapy play a vital role in assisting clinicians in counseling patients regarding likely toxicities. Precise prediction and evaluation of…

Machine Learning · Computer Science 2024-11-19 Yang Yan , Zhong Chen , Cai Xu , Xinglei Shen , Jay Shiao , John Einck , Ronald C Chen , Hao Gao

The complexity and variability inherent in high-resolution pathological images present significant challenges in computational pathology. While pathology foundation models leveraging AI have catalyzed transformative advancements, their…

Artificial intelligence has started to transform histopathology impacting clinical diagnostics and biomedical research. However, while many computational pathology approaches have been proposed, most current AI models are limited with…

Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka
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