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Timing is of fundamental importance in biology and our life. Borrowing ideas from mechanism, we map our clock signals onto a gear system, in pursuit of better depiction of a clock signal implemented with chemical reaction networks (CRNs).…

Molecular Networks · Quantitative Biology 2018-02-23 Chuan Zhang , Lulu Ge , Xiaohu You

Efficient tuning of building climate controllers to optimize occupant utility is essential for ensuring overall comfort and satisfaction. However, this is a challenging task since the latent utility are difficult to measure directly.…

Systems and Control · Electrical Eng. & Systems 2025-12-11 Wenbin Wang , Jicheng Shi , Colin N. Jones

Dynamically crosslinked semiflexible biopolymers such as the actin cytoskeleton govern the mechanical behavior of living cells. Semiflexible biopolymers nonlinearly stiffen in response to mechanical loads, whereas the crosslinker dynamics…

Soft Condensed Matter · Physics 2019-06-05 Yuval Mulla , F. C. MacKintosh , Gijsje H. Koenderink

Because organisms are able to sense its passage, it is perhaps tempting to treat time as a sensory modality, akin to vision or audition. Indeed, certain features of sensory estimation, such as Weber's law, apply to timing and sensation…

Neurons and Cognition · Quantitative Biology 2025-04-01 Caroline Haimerl , Filipe S. Rodrigues , Joseph J. Paton

A possible mechanism of time is formulated by developing an idea of time replaced by quantum correlations, with the aid of modern quantum information theory. We invent a microscopic model, where correlations of a closed system are steadily…

Quantum Physics · Physics 2011-11-14 Akimasa Miyake

Continuous stress forecasting could potentially contribute to lifestyle interventions. This paper presents a novel, explainable, and individualized approach for stress prediction using physiological data from consumer-grade smartwatches. We…

Machine Learning · Computer Science 2026-02-24 Xueyi Wang , Claudine J. C. Lamoth , Elisabeth Wilhelm

Theoretical arguments and empirical evidence in neuroscience suggests that organisms represent or model their environment by minimizing a variational free-energy bound on the surprise associated with sensory signals from the environment. In…

Neurons and Cognition · Quantitative Biology 2017-05-24 Biswa Sengupta , Karl Friston

Among the fundamental questions in computer science is that of the impact of synchronism/asynchronism on computations, which has been addressed in various fields of the discipline: in programming, in networking, in concurrence theory, in…

Cellular Automata and Lattice Gases · Physics 2024-03-13 Isabel Donoso Leiva , Eric Goles , Martín Ríos-Wilson , Sylvain Sené

The mechanosensitivity of cells, which determines how they are able to respond to mechanical signals received from their environment, is crucial for the functioning of all biological systems. In experiments, cells placed on cyclically…

Biological Physics · Physics 2019-01-17 John J. Molina , Ryoichi Yamamoto

Neurons in early sensory areas rapidly adapt to changing sensory statistics, both by normalizing the variance of their individual responses and by reducing correlations between their responses. Together, these transformations may be viewed…

Neurons and Cognition · Quantitative Biology 2023-10-27 Lyndon R. Duong , Eero P. Simoncelli , Dmitri B. Chklovskii , David Lipshutz

Collective decision-making arises from individual agents integrating their own personal observations with information obtained from social partners. In many biological systems that exhibit collective decision-making, the process by which…

Quantitative Methods · Quantitative Biology 2026-04-28 Ling-Wei Kong , Naomi Ehrich Leonard , Andrew M. Hein

Adaptation in the retina is thought to optimize the encoding of natural light signals into sequences of spikes sent to the brain. However, adaptation also entails computational costs: adaptive code is intrinsically ambiguous, because output…

Neurons and Cognition · Quantitative Biology 2014-01-28 Gašper Tkačik , Anandamohan Ghosh , Elad Schneidman , Ronen Segev

We propose the use of optical lattice clocks operated with fermionic alkaline-earth-atoms to study spin-orbit coupling (SOC) in interacting many-body systems. The SOC emerges naturally during the clock interrogation when atoms are allowed…

Plants have developed intricate mechanisms to adapt to changing light conditions. Besides photo- and helio- tropism -- the differential growth towards light and the diurnal motion with respect to sunlight -- chloroplast motion acts as a…

Soft Condensed Matter · Physics 2023-02-22 Nico Schramma , Cintia Perugachi Israëls , Maziyar Jalaal

Two remote agents with synchronized clocks may use them to act in concert and communicate. This necessitates some means of creating and maintaining synchrony. One method, not requiring any direct interaction between the agents, is to expose…

Statistical Mechanics · Physics 2026-05-20 Benjamin Sorkin , Thomas A. Witten

Quantum time dilation occurs when a clock moves in a superposition of relativistic momentum wave packets. We utilize the lifetime of an excited hydrogen-like atom as a clock to demonstrate how quantum time dilation manifests in a…

Quantum Physics · Physics 2021-04-28 Piotr T. Grochowski , Alexander R. H. Smith , Andrzej Dragan , Kacper Dębski

Circadian and other physiological rhythms play a key role in both normal homeostasis and disease processes. Such is the case of circadian and infradian seizure patterns observed in epilepsy. In this paper we explore a new implantable…

A composite, exponential relaxation function, modulated by a periodic component, was used to fit to an experimental time series of blood glucose levels. The 11 parameters function that allows for the detection of a possible rhythm…

Quantitative Methods · Quantitative Biology 2008-01-30 Baruch Vainas

A novel viewpoint, i.e., adaptive synchronization, is proposed to explore collective rhythm observed in many complex, self-organizing systems. We show that a simple adaptive coupling is able to tip arrays of oscillators towards collective…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Debin Huang

We show that the unavoidable increase in neuronal response latency to ongoing stimulation serves as a nonuniform gradual stretching of neuronal circuit delay loops and emerges as an essential mechanism in the formation of various types of…

Neurons and Cognition · Quantitative Biology 2012-12-07 Roni Vardi , Reut Timor , Shimon Marom , Moshe Abeles , Ido Kanter
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