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Related papers: Phenotypic Profiling of High Throughput Imaging Sc…

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Morphological profiling is a valuable tool in phenotypic drug discovery. The advent of high-throughput automated imaging has enabled the capturing of a wide range of morphological features of cells or organisms in response to perturbations…

High-content screening uses large collections of unlabeled cell image data to reason about genetics or cell biology. Two important tasks are to identify those cells which bear interesting phenotypes, and to identify sub-populations enriched…

Machine Learning · Computer Science 2015-01-08 Lee Zamparo , Zhaolei Zhang

Clustering artworks is difficult for several reasons. On the one hand, recognizing meaningful patterns in accordance with domain knowledge and visual perception is extremely difficult. On the other hand, applying traditional clustering and…

Computer Vision and Pattern Recognition · Computer Science 2020-10-23 Giovanna Castellano , Gennaro Vessio

Hyperspectral images (HSI) not only have a broad macroscopic field of view but also contain rich spectral information, and the types of surface objects can be identified through spectral information, which is one of the main applications in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Sen Jia , Yifan Wang

Recent advances in self-supervised deep learning have improved our ability to quantify cellular morphological changes in high-throughput microscopy screens, a process known as morphological profiling. However, most current methods only…

Machine Learning · Computer Science 2026-05-18 Yemin Yu , Emre Hayir , Neil Tenenholtz , Lester Mackey , Ying Wei , David Alvarez-Melis , Ava P. Amini , Alex X. Lu

The use of Deep Learning (DL) based methods in medical histopathology images have been one of the most sought after solutions to classify, segment, and detect diseased biopsy samples. However, given the complex nature of medical datasets…

Computer Vision and Pattern Recognition · Computer Science 2022-02-23 Suvidha Tripathi , Satish Kumar Singh

High-dimensional and complex spectral structures make the clustering of hyperspectral images (HSI) a challenging task. Subspace clustering is an effective approach for addressing this problem. However, current subspace clustering algorithms…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Renxiang Guan , Zihao Li , Xianju Li , Chang Tang , Ruyi Feng

In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. However, existing methods require computationally extensive and complex multi-step…

Machine Learning · Computer Science 2025-02-28 Bo Li , Bob Zhang , Chengyang Zhang , Minghao Zhou , Weiliang Huang , Shihang Wang , Qing Wang , Mengran Li , Yong Zhang , Qianqian Song

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Richard J. Chen , Rahul G. Krishnan

High-dimensional and complex spectral structures make clustering of hy-perspectral images (HSI) a challenging task. Subspace clustering has been shown to be an effective approach for addressing this problem. However, current subspace…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Xianju Li , Renxiang Guan , Zihao Li , Hao Liu , Jing Yang

Image clustering is a crucial but challenging task in multimedia machine learning. Recently the combination of clustering with deep learning has achieved promising performance against conventional methods on high-dimensional image data.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Ruilin Zhang , Haiyang Zheng , Hongpeng Wang

Definitive cancer diagnosis and management depend upon the extraction of information from microscopy images by pathologists. These images contain complex information requiring time-consuming expert human interpretation that is prone to…

Despite significant advances in clustering methods in recent years, the outcome of clustering of a natural image dataset is still unsatisfactory due to two important drawbacks. Firstly, clustering of images needs a good feature…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Dipanjan Das , Ratul Ghosh , Brojeshwar Bhowmick

We present a general methodology that learns to classify images without labels by leveraging pretrained feature extractors. Our approach involves self-distillation training of clustering heads based on the fact that nearest neighbours in…

Computer Vision and Pattern Recognition · Computer Science 2023-11-13 Nikolas Adaloglou , Felix Michels , Hamza Kalisch , Markus Kollmann

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ha Anh Vu

This paper proposes a novel deep subspace clustering approach which uses convolutional autoencoders to transform input images into new representations lying on a union of linear subspaces. The first contribution of our work is to insert…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Mohsen Kheirandishfard , Fariba Zohrizadeh , Farhad Kamangar

Unsupervised disentangled representation learning is a long-standing problem in computer vision. This work proposes a novel framework for performing image clustering from deep embeddings by combining instance-level contrastive learning with…

Machine Learning · Computer Science 2021-10-05 Ramakrishnan Sundareswaran , Jansel Herrera-Gerena , John Just , Ali Jannesari

The detailed analysis of molecular structures and properties holds great potential for drug development discovery through machine learning. Developing an emergent property in the model to understand molecules would broaden the horizons for…

Finding a template in a search image is an important task underlying many computer vision applications. Recent approaches perform template matching in a deep feature-space, produced by a convolutional neural network (CNN), which is found to…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Bo Gao , M. W. Spratling

Identifying subtle phenotypic variations in cellular images is critical for advancing biological research and accelerating drug discovery. These variations are often masked by the inherent cellular heterogeneity, making it challenging to…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Anis Bourou , Biel Castaño Segade , Thomas Boyer , Valérie Mezger , Auguste Genovesio
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