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We consider the inverse problem of identifying parameters in a variant of the diffuse interface model for tumour growth model proposed by Garcke, Lam, Sitka and Styles (Math. Models Methods Appl. Sci. 2016). The model contains three…

Optimization and Control · Mathematics 2017-07-24 Christian Kahle , Kei Fong Lam

We investigate solution methods for large-scale inverse problems governed by partial differential equations (PDEs) via Bayesian inference. The Bayesian framework provides a statistical setting to infer uncertain parameters from noisy…

Applications · Statistics 2023-02-08 Mina Karimi , Mehrdad Massoudi , Kaushik Dayal , Matteo Pozzi

In this paper, we derive an effective model for transport processes in periodically perforated elastic media, taking into account, e.g., cyclic elastic deformations as they occur in lung tissue due to respiratory movement. The underlying…

Analysis of PDEs · Mathematics 2022-06-15 Jonas Knoch , Markus Gahn , Maria Neuss-Radu , Nicolas Neuß

We consider an \eps-approximation by n-term partial sums of the Karhunen-Lo\`eve expansion to d-parametric random fields of tensor product-type in the average case setting. We investigate the behavior, as d tends to infinity, of the…

Probability · Mathematics 2012-08-15 N. Serdyukova

The diffusive transport distance, a novel pseudo-metric between probability measures on the real line, is introduced. It generalizes Martingale optimal transport, and forms a hierarchy with the Hellinger and the Wasserstein metrics. We…

Analysis of PDEs · Mathematics 2025-01-27 Daniel Matthes , Eva-Maria Rott , André Schlichting

We develop a new approach for detecting changes in the behavior of stochastic processes and random fields based on tensor product representations such as the Karhunen-Lo\`{e}ve expansion. From the associated eigenspaces of the covariance…

Probability · Mathematics 2023-11-21 Julio Enrique Castrillon-Candas , Mark Kon

In this work, we consider a diffuse interface model for tumour growth in the presence of a nutrient which is consumed by the tumour. The system of equations consists of a Cahn--Hilliard equation with source terms for the tumour cells and a…

Numerical Analysis · Mathematics 2022-05-09 Harald Garcke , Dennis Trautwein

We use Langevin dynamics simulations to study the mass diffusion problem across two adjacent porous layers of different transport property. At the interface between the layers, we impose the Kedem-Katchalsky (KK) interfacial boundary…

Computational Physics · Physics 2020-08-06 Oded Farago , Giuseppe Pontrelli

A dynamical low-rank approximation is developed for reduced-order modeling (ROM) of the filtered density function (FDF) transport equation, which is utilized for large eddy simulation (LES) of turbulent reacting flows. In this methodology,…

Fluid Dynamics · Physics 2025-03-25 Aidyn Aitzhan , Peyman Givi , Hessam Babaee

We consider a (degenerate) cross-diffusion model of tumor growth structured by phenotypic trait. We prove the existence of weak solutions and the incompressible limit as the pressure becomes stiff extending methods recently introduced in…

Analysis of PDEs · Mathematics 2023-04-04 Noemi David

We derive concentration inequalities for the supremum norm of the difference between a kernel density estimator (KDE) and its point-wise expectation that hold uniformly over the selection of the bandwidth and under weaker conditions on the…

Statistics Theory · Mathematics 2020-01-01 Jisu Kim , Jaehyeok Shin , Alessandro Rinaldo , Larry Wasserman

Partial differential equations (PDEs) are central to computational electromagnetics (CEM) and photonic design, but classical solvers face high costs for large or complex structures. Quantum Hamiltonian simulation provides a framework to…

Quantum Physics · Physics 2025-10-07 Hiroyuki Tezuka , Yuki Sato

We study the permeability and selectivity (`permselectivity') of model membranes made of polydisperse polymer networks for molecular penetrant transport, using coarse-grained, implicit-solvent computer simulations. The permeability…

Soft Condensed Matter · Physics 2020-09-30 Won Kyu Kim , Richard Chudoba , Sebastian Milster , Rafael Roa , Matej Kanduc , Joachim Dzubiella

Transport map methods offer a powerful statistical learning tool that can couple a target high-dimensional random variable with some reference random variable using invertible transformations. This paper presents new computational…

Numerical Analysis · Mathematics 2023-03-07 Tiangang Cui , Sergey Dolgov , Olivier Zahm

We study the behaviour of linear perturbations in multifield coupled quintessence models. Using gauge invariant linear cosmological perturbation theory we provide the full set of governing equations for this class of models, and solve the…

Cosmology and Nongalactic Astrophysics · Physics 2017-06-21 Alexander Leithes , Karim A. Malik , David J. Mulryne , Nelson J. Nunes

In this paper, we develop a sharp interface tumor growth model to study the effect of the tumor microenvironment using a complex far-field geometry that mimics a heterogeneous distribution of vasculature. Together with different nutrient…

Numerical Analysis · Mathematics 2020-03-20 Min-Jhe Lu , Chun Liu , John Lowengrub , Shuwang Li

We provide a quantitative picture of non-conserved interface growth from a diffusive field making special emphasis on two main issues, the range of validity of the effective small-slopes (interfacial) theories and the interplay between the…

Statistical Mechanics · Physics 2009-11-13 Matteo Nicoli , Mario Castro , Rodolfo Cuerno

Diffusive transport is a universal phenomenon, throughout both biological and physical sciences, and models of diffusion are routinely used to interrogate diffusion-driven processes. However, most models neglect to take into account the…

Quantitative Methods · Quantitative Biology 2015-10-28 Paul R. Taylor , Christian A. Yates , Matthew J. Simpson , Ruth E. Baker

Systems under external confinement and constraints often show interesting properties. In this thesis, we study some systems under external confinement. We begin by finding out the probability distribution of end-to-end separation of a Worm…

Soft Condensed Matter · Physics 2007-05-23 Debasish Chaudhuri

Growth and roughness of the interface of deposited polymer chains driven by a field onto an impenetrable adsorbing surface are studied by computer simulations in (2+1) dimensions. The evolution of the interface width W shows a crossover…

Soft Condensed Matter · Physics 2007-05-23 Frank W. Bentrem , R. B. Pandey , Fereydoon Family
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