Related papers: Towards Unsupervised Cancer Subtyping: Predicting …
Cancer subtyping plays a crucial role in informing prognosis and guiding personalized treatment strategies. However, conventional subtyping approaches often rely on static, biopsy-derived scores that hardly capture the biological…
Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…
We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…
Recently, bladder cancer has been significantly increased in terms of incidence and mortality. Currently, two subtypes are known based on tumour growth: non-muscle invasive (NMIBC) and muscle-invasive bladder cancer (MIBC). In this work, we…
Image clustering is a particularly challenging computer vision task, which aims to generate annotations without human supervision. Recent advances focus on the use of self-supervised learning strategies in image clustering, by first…
Medical image analysis using supervised deep learning methods remains problematic because of the reliance of deep learning methods on large amounts of labelled training data. Although medical imaging data repositories continue to expand…
Purpose: Lesion segmentation in medical imaging is key to evaluating treatment response. We have recently shown that reinforcement learning can be applied to radiological images for lesion localization. Furthermore, we demonstrated that…
Prediction of survival for cancer patients is an open area of research. However, many of these studies focus on datasets with a large number of patients. We present a novel method that is specifically designed to address the challenge of…
Screening is critical for prevention and early detection of cervical cancer but it is time-consuming and laborious. Supervised deep convolutional neural networks have been developed to automate pap smear screening and the results are…
We explore unsupervised machine learning for galaxy morphology analyses using a combination of feature extraction with a vector-quantised variational autoencoder (VQ-VAE) and hierarchical clustering (HC). We propose a new methodology that…
The lack of large labeled medical imaging datasets, along with significant inter-individual variability compared to clinically established disease classes, poses significant challenges in exploiting medical imaging information in a…
Hematoxylin and Eosin stained histopathology image analysis is essential for the diagnosis and study of complicated diseases such as cancer. Existing state-of-the-art approaches demand extensive amount of supervised training data from…
Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…
In this paper we develop a new unsupervised machine learning technique comprised of a feature extractor, a convolutional autoencoder (CAE), and a clustering algorithm consisting of a Bayesian Gaussian mixture model (BGM). We apply this…
Precision medicine is a paradigm shift in healthcare relying heavily on genomics data. However, the complexity of biological interactions, the large number of genes as well as the lack of comparisons on the analysis of data, remain a…
Histomorphology is crucial in cancer diagnosis. However, existing whole slide image (WSI) classification methods struggle to effectively incorporate histomorphology information, limiting their ability to capture key pathological features.…
Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…
In this work, we update the unsupervised machine learning (UML) step by proposing an algorithm based on ConvNeXt large model coding to improve the efficiency of unlabeled galaxy morphology classifications. The method can be summarized into…
Designing deep learning algorithms for gland segmentation is crucial for automatic cancer diagnosis and prognosis, yet the expensive annotation cost hinders the development and application of this technology. In this paper, we make a first…
This paper presents a novel method for unsupervised segmentation of pathology images. Staging of lung cancer is a major factor of prognosis. Measuring the maximum dimensions of the invasive component in a pathology images is an essential…