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We study the Cahn-Hilliard-Biot model with respect to its mathematical well-posedness. The system models flow through deformable porous media in which the solid material has two phases with distinct material properties. The two phases of…

Analysis of PDEs · Mathematics 2024-10-04 Marvin Fritz

Inverse Stefan problem arising in modeling of laser ablation of biomedical tissues is analyzed, where information on the coefficients, heat flux on the fixed boundary, and density of heat sources are missing and must be found along with the…

Analysis of PDEs · Mathematics 2017-10-25 Ugur G. Abdulla , Jonathan Goldfarb

A phase field model for tumour growth is introduced that is based on a Brinkman law for convective velocity fields. The model couples a convective Cahn-Hilliard equation for the evolution of the tumour to a reaction-diffusion-advection…

Analysis of PDEs · Mathematics 2021-09-07 Matthias Ebenbeck , Harald Garcke , Robert Nürnberg

The initial boundary value problem for a Cahn-Hilliard system subject to a dynamic boundary condition of Allen-Cahn type is treated. The vanishing of the surface diffusion on the dynamic boundary condition is the point of emphasis. By the…

Analysis of PDEs · Mathematics 2020-04-20 Pierluigi Colli , Takeshi Fukao

We consider a stochastic system whose uncontrolled state dynamics are modelled by a general one-dimensional It\^{o} diffusion. The control effort that can be applied to this system takes the form that is associated with the so-called…

Probability · Mathematics 2007-11-15 Andrew J. F. Jack , Timothy C. Johnson , Mihail Zervos

We consider a class of closed loop stochastic optimal control problems in finite time horizon, in which the cost is an expectation conditional on the event that the process has not exited a given bounded domain. An important difficulty is…

Optimization and Control · Mathematics 2019-12-19 Yves Achdou , Mathieu Laurière , Pierre-Louis Lions

We propose a general framework for studying optimal impulse control problem in the presence of uncertainty on the parameters. Given a prior on the distribution of the unknown parameters, we explain how it should evolve according to the…

Probability · Mathematics 2017-12-06 N. Baradel , B. Bouchard , Ngoc Minh Dang

Control systems involving unknown parameters appear a natural framework for applications in which the model design has to take into account various uncertainties. In these circumstances the performance criterion can be given in terms of an…

Optimization and Control · Mathematics 2019-01-15 Piernicola Bettiol , Nathalie Khalil

We propose a mean-field optimal control problem for the parameter identification of a given pattern. The cost functional is based on the Wasserstein distance between the probability measures of the modeled and the desired patterns. The…

Optimization and Control · Mathematics 2021-04-08 Martin Burger , Lisa Maria Kreusser , Claudia Totzeck

The paper considers the optimal control problem of inventory of a discrete product in regeneration scheme with a Poisson flow of customer requirements. In the system deferred demand is allowed, the volume of which is limited by a given…

Optimization and Control · Mathematics 2020-01-31 P. V. Shnurkov , N. A. Vakhtanov

In this work, we study a model consisting of a Cahn-Hilliard-type equation for the concentration of tumour cells coupled to a reaction-diffusion type equation for the nutrient density and a Brinkman-type equation for the velocity. We equip…

Analysis of PDEs · Mathematics 2018-11-19 Matthias Ebenbeck , Harald Garcke

Tumor growth beyond a critical size relies on the development of a functional vascular network, which ensures adequate oxygen and nutrient supply. In this work, we present a modeling framework based on an optimization-based 3D-1D coupling…

Numerical Analysis · Mathematics 2026-04-01 Chiara Giverso , Denise Grappein , Stefano Scialò

We consider a stochastic control problem where the set of strict (classical) controls is not necessarily convex and the the variable control has two components, the first being absolutely continuous and the second singular. The system is…

Probability · Mathematics 2008-12-20 Seid Bahlali

Stochastic maximum principle of nonlinear controlled forward-backward systems, where the set of strict (classical) controls need not be convex and the diffusion coefficient depends explicitly on the variable control, is an open problem…

Probability · Mathematics 2008-12-20 Seid Bahlali

The interactions between tumor cells and the immune system play a crucial role in cancer evolution. In this study, we explore how these interactions influence cancer progression by modeling the relationships among naive T cells, effector T…

Tissues and Organs · Quantitative Biology 2025-03-19 Haifeng Zhang , Changjing Zhuge , Jinzhi Lei

We derive a Cahn-Hilliard-Darcy model to describe multiphase tumour growth taking interactions with multiple chemical species into account as well as the simultaneous occurrence of proliferating, quiescent and necrotic regions. Via a…

Analysis of PDEs · Mathematics 2019-11-01 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Emanuel Sitka

We consider an optimal control problem where the state is governed by a free boundary problem called the two-phase membrane problem and the control appears in the coefficients of the characteristic function of the positivity and negativity…

Optimization and Control · Mathematics 2024-05-20 Farid Bozorgnia , Vyacheslav Kungurtsev

The scope of this paper is the analysis and approximation of an optimal control problem related to the Allen-Cahn equation. A tracking functional is minimized subject to the Allen-Cahn equation using distributed controls that satisfy…

Numerical Analysis · Mathematics 2022-07-27 Konstantinos Chrysafinos , Dimitra Plaka

Controlled one-dimensional diffusion processes, with infinitesimal variance (instead of the infinitesimal mean) depending on the control variable, are considered in an interval located on the positive half-line. The process is controlled…

Probability · Mathematics 2007-05-23 Mario Lefebvre

In this paper, co-states are used to develop a framework that desensitizes the optimal cost. A general formulation for an optimal control problem with fixed final time is considered. The proposed scheme involves elevating the parameters of…

Optimization and Control · Mathematics 2019-10-02 Venkata Ramana Makkapati , Dipankar Maity , Mehregan Dor , Panagiotis Tsiotras