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Predicting enzyme-substrate interactions has long been a fundamental problem in biochemistry and metabolic engineering. While existing methods could leverage databases of expert-curated enzyme-substrate pairs for models to learn from known…

Artificial Intelligence · Computer Science 2026-01-12 Tengwei Song , Long Yin , Zhen Han , Zhiqiang Xu

Knowledge graph embedding aims to embed entities and relations of knowledge graphs into low-dimensional vector spaces. Translating embedding methods regard relations as the translation from head entities to tail entities, which achieve the…

Artificial Intelligence · Computer Science 2018-01-10 Denghui Zhang , Manling Li , Yantao Jia , Yuanzhuo Wang , Xueqi Cheng

Knowledge graph reasoning, which aims at predicting the missing facts through reasoning with the observed facts, is critical to many applications. Such a problem has been widely explored by traditional logic rule-based approaches and recent…

Machine Learning · Computer Science 2019-10-30 Meng Qu , Jian Tang

Reasoning, the ability to logically draw conclusions from existing knowledge, is a hallmark of human. Together with perception, they constitute the two major themes of artificial intelligence. While deep learning has pushed the limit of…

Artificial Intelligence · Computer Science 2024-10-18 Zhaocheng Zhu

This paper proposes an algorithm named as PrTransH to learn embedding vectors from real world EMR data based medical knowledge. The unique challenge in embedding medical knowledge graph from real world EMR data is that the uncertainty of…

Artificial Intelligence · Computer Science 2020-11-10 Linfeng Li , Peng Wang , Yao Wang , Jinpeng Jiang , Buzhou Tang , Jun Yan , Shenghui Wang , Yuting Liu

Recent advances in information extraction have motivated the automatic construction of huge Knowledge Graphs (KGs) by mining from large-scale text corpus. However, noisy facts are unavoidably introduced into KGs that could be caused by…

Computation and Language · Computer Science 2020-08-18 Yaqing Wang , Fenglong Ma , Jing Gao

Knowledge graph (KG) embedding seeks to learn vector representations for entities and relations. Conventional models reason over graph structures, but they suffer from the issues of graph incompleteness and long-tail entities. Recent…

Computation and Language · Computer Science 2022-09-16 Yang Liu , Zequn Sun , Guangyao Li , Wei Hu

Knowledge bases often consist of facts which are harvested from a variety of sources, many of which are noisy and some of which conflict, resulting in a level of uncertainty for each triple. Knowledge bases are also often incomplete,…

Artificial Intelligence · Computer Science 2021-04-13 Xuelu Chen , Michael Boratko , Muhao Chen , Shib Sankar Dasgupta , Xiang Lorraine Li , Andrew McCallum

Knowledge Graph Completion (KGC) aims to predict the missing information in the (head entity)-[relation]-(tail entity) triplet. Deep Neural Networks have achieved significant progress in the relation prediction task. However, most existing…

Computation and Language · Computer Science 2024-08-15 Pengjie Liu

Embedding entities and relations into a continuous multi-dimensional vector space have become the dominant method for knowledge graph embedding in representation learning. However, most existing models ignore to represent hierarchical…

Artificial Intelligence · Computer Science 2019-09-12 Cunxiang Wang , Feiliang Ren , Zhichao Lin , Chenxv Zhao , Tian Xie , Yue Zhang

Graph neural networks have been widely used for learning representations of nodes for many downstream tasks on graph data. Existing models were designed for the nodes on a single graph, which would not be able to utilize information across…

Machine Learning · Computer Science 2021-06-04 Meng Jiang

Over the past years, embedding learning on networks has shown tremendous results in link prediction tasks for complex systems, with a wide range of real-life applications. Learning a representation for each node in a knowledge graph allows…

Machine Learning · Computer Science 2026-02-03 Orell Trautmann , Olaf Wolkenhauer , Clémence Réda

Recently, neural network based methods have shown their power in learning more expressive features on the task of knowledge graph embedding (KGE). However, the performance of deep methods often falls behind the shallow ones on simple…

Computation and Language · Computer Science 2022-11-10 Zhu Danhao , Shen Si , Huang Shujian , Yin Chang , Ding Ziqi

The human proteome contains a vast network of interacting kinases and substrates. Even though some kinases have proven to be immensely useful as therapeutic targets, a majority are still understudied. In this work, we present a novel…

Quantitative Methods · Quantitative Biology 2022-06-13 Sachin Gavali , Karen Ross , Chuming Chen , Julie Cowart , Cathy H. Wu

Transformer architectures, capable of capturing sequential dependencies in the history of user interactions, have become the dominant approach in sequential recommender systems. Despite their success, such models consider sequence elements…

Information Retrieval · Computer Science 2026-03-02 Artur Gimranov , Viacheslav Yusupov , Elfat Sabitov , Tatyana Matveeva , Anton Lysenko , Ruslan Israfilov , Evgeny Frolov

A knowledge graph (KG) is a data structure which represents entities and relations as the vertices and edges of a directed graph with edge types. KGs are an important primitive in modern machine learning and artificial intelligence.…

Artificial Intelligence · Computer Science 2021-10-20 Michael R. Douglas , Michael Simkin , Omri Ben-Eliezer , Tianqi Wu , Peter Chin , Trung V. Dang , Andrew Wood

Knowledge graphs are inherently incomplete. Therefore substantial research has been directed toward knowledge graph completion (KGC), i.e., predicting missing triples from the information represented in the knowledge graph (KG). KG…

Machine Learning · Computer Science 2023-03-23 Aleksandar Pavlović , Emanuel Sallinger

Knowledge Graphs are a widely used method to represent relations between entities in various AI applications, and Graph Embedding has rapidly become a standard technique to represent Knowledge Graphs in such a way as to facilitate…

Machine Learning · Computer Science 2023-11-02 Zhijin Guo , Zhaozhen Xu , Martha Lewis , Nello Cristianini

In recent years, knowledge graphs have gained interest and witnessed widespread applications in various domains, such as information retrieval, question-answering, recommendation systems, amongst others. Large-scale knowledge graphs to this…

Machine Learning · Computer Science 2024-10-29 Arnab Sharma , N'Dah Jean Kouagou , Axel-Cyrille Ngonga Ngomo

Many knowledge graph embedding methods operate on triples and are therefore implicitly limited by a very local view of the entire knowledge graph. We present a new framework MOHONE to effectively model higher order network effects in…

Computation and Language · Computer Science 2018-11-02 Hao Yu , Vivek Kulkarni , William Wang