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A simple DNA-based data storage scheme is demonstrated in which information is written using "addressing" oligonucleotides. In contrast to other methods that allow arbitrary code to be stored, the resulting DNA is suitable for downstream…

Emerging Technologies · Computer Science 2017-11-15 Gary M. Skinner , Koen Visscher , Masud Mansuripur

Owing to its longevity and enormous information density, DNA, the molecule encoding biological information, has emerged as a promising archival storage medium. However, due to technological constraints, data can only be written onto many…

Emerging Technologies · Computer Science 2018-03-12 Reinhard Heckel , Gediminas Mikutis , Robert N. Grass

I introduce a formalism for representing the syntax of recursively structured graph-like patterns. It does not use production rules, like a conventional graph grammar, but represents the syntactic structure in a more direct and declarative…

Formal Languages and Automata Theory · Computer Science 2025-04-25 Peter Fletcher

Usage of multiprocessor and multicore computers implies parallel programming. Tools for preparing parallel programs include parallel languages and libraries as well as parallelizing compilers and convertors that can perform automatic…

Mathematical Software · Computer Science 2022-12-12 Pavel Telegin , Anton Baranov , Boris Shabanov , Artem Tikhomirov

In this paper, we propose a new approach of network performance analysis, which is based on our previous works on the deterministic network analysis using the Gaussian approximation (DNA-GA). First, we extend our previous works to a…

Information Theory · Computer Science 2017-09-27 Ming Ding , David Lopez Perez , Guoqiang Mao , Zihuai Lin

Recent advances in image data processing through machine learning and especially deep neural networks (DNNs) allow for new optimization and performance-enhancement schemes for radiation detectors and imaging hardware through data-endowed…

Instrumentation and Detectors · Physics 2024-02-23 S. Lin , S. Ning , H. Zhu , T. Zhou , C. L. Morris , S. Clayton , M. Cherukara , R. T. Chen , Z. Wang

Rule-based reasoning is an essential part of human intelligence prominently formalized in artificial intelligence research via logic programs. Describing complex objects as the composition of elementary ones is a common strategy in computer…

Artificial Intelligence · Computer Science 2023-12-15 Christian Antic

Upcoming many core processors are expected to employ a distributed memory architecture similar to currently available supercomputers, but parallel pattern mining algorithms amenable to the architecture are not comprehensively studied. We…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-10-28 Kazuki Yoshizoe , Aika Terada , Koji Tsuda

Graph Neural Networks (GNNs) are an emerging research field. This specialized Deep Neural Network (DNN) architecture is capable of processing graph structured data and bridges the gap between graph processing and Deep Learning (DL). As…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-24 Jana Vatter , Ruben Mayer , Hans-Arno Jacobsen

With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, we need a revolutionary sequencing method for the…

Biological Physics · Physics 2008-01-03 Michael Zwolak , Massimiliano Di Ventra

Blockchain technology is among the fastest-growing technologies in the world today. It has been adopted in diverse areas but mostly in financial systems, such as Bitcoin cryptocurrency. Therefore, it is a niche that has attracted interest…

Cryptography and Security · Computer Science 2021-06-30 Mabrook S. Al-Rakhami , Abdu Gumaei , Sk. Md. Mizanur Rahman , Atif Al-Amri

DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding…

Information Theory · Computer Science 2025-04-22 Ruiying Cao , Xin Chen

The central dogma of molecular biology is the principal framework for understanding how nucleic acid information is propagated and used by living systems to create complex biomolecules. Here, by integrating the structural and dynamic…

Biological Physics · Physics 2018-10-04 Jihoon Shin , Junghoon Kim , Sung Ha Park , Tai Hwan Ha

Deep learning-based AI models have been extensively applied in genomics, achieving remarkable success across diverse applications. As these models gain prominence, there exists an urgent need for interpretability methods to establish…

Genomics · Quantitative Biology 2025-05-16 Chenyu Wang , Chaoying Zuo , Zihan Su , Yuhang Xing , Lu Li , Maojun Wang , Zeyu Zhang

Sequence labeling (SL) is a fundamental research problem encompassing a variety of tasks, e.g., part-of-speech (POS) tagging, named entity recognition (NER), text chunking, etc. Though prevalent and effective in many downstream applications…

Computation and Language · Computer Science 2020-11-16 Zhiyong He , Zanbo Wang , Wei Wei , Shanshan Feng , Xianling Mao , Sheng Jiang

Mathematical reasoning is a fundamental aspect of human intelligence and is applicable in various fields, including science, engineering, finance, and everyday life. The development of artificial intelligence (AI) systems capable of solving…

Artificial Intelligence · Computer Science 2023-06-23 Pan Lu , Liang Qiu , Wenhao Yu , Sean Welleck , Kai-Wei Chang

The success of graphene for nanopore DNA sequencing has shown that it is possible to explore other potential single- and few-atom thick layers of 2D materials beyond graphene, and also that these materials can exhibit fascinating and…

Mesoscale and Nanoscale Physics · Physics 2022-01-19 Benjamin O. Tayo

Recent progress on salient object detection mainly aims at exploiting how to effectively integrate multi-scale convolutional features in convolutional neural networks (CNNs). Many popular methods impose deep supervision to perform…

Computer Vision and Pattern Recognition · Computer Science 2021-01-21 Yun Liu , Ming-Ming Cheng , Xinyu Zhang , Guang-Yu Nie , Meng Wang

Advancements in genomic research such as high-throughput sequencing techniques have driven modern genomic studies into "big data" disciplines. This data explosion is constantly challenging conventional methods used in genomics. In parallel…

Genomics · Quantitative Biology 2023-10-06 Tianwei Yue , Yuanxin Wang , Longxiang Zhang , Chunming Gu , Haoru Xue , Wenping Wang , Qi Lyu , Yujie Dun

DNA data storage systems encode digital data into DNA strands, enabling dense and durable storage. Efficient data retrieval depends on coverage depth, a key performance metric. We study the random access coverage depth problem and focus on…

Information Theory · Computer Science 2025-07-29 Şeyma Bodur , Stefano Lia , Hiram H. López , Rati Ludhani , Alberto Ravagnani , Lisa Seccia