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The reshaping and decorrelation of similar activity patterns by neuronal networks can enhance their discriminability, storage, and retrieval. How can such networks learn to decorrelate new complex patterns, as they arise in the olfactory…

Neurons and Cognition · Quantitative Biology 2015-06-04 Siu-Fai Chow , Stuart D. Wick , Hermann Riecke

One of the key challenges to predict odor from molecular structure is unarguably our limited understanding of the odor space and the complexity of the underlying structure-odor relationships. Here, we show that the predictive performance of…

Quantitative Methods · Quantitative Biology 2025-08-14 Akshay Sajan , Stijn Sluis , Reza Haydarlou , Sanne Abeln , Pasquale Lisena , Raphael Troncy , Caro Verbeek , Inger Leemans , Halima Mouhib

Odor sensory evaluation has a broad application in food, clothing, cosmetics, and other fields. Traditional artificial sensory evaluation has poor repeatability, and the machine olfaction represented by the electronic nose (E-nose) is…

Artificial Intelligence · Computer Science 2023-11-27 Xiuxin Xia , Yuchen Guo , Yanwei Wang , Yuchao Yang , Yan Shi , Hong Men

This work presents a general chemical reaction network theory for olfactory sensing processes that employ G-protein-coupled receptors as olfactory receptors (ORs). The theory is applicable to general mixtures of odorants and an arbitrary…

Molecular Networks · Quantitative Biology 2023-09-06 Won Kyu Kim , Kiri Choi , Changbong Hyeon , Seogjoo J. Jang

Mitral cells, the principal neurons in the olfactory bulb, respond to odorants by firing bursts of action potentials called sharp events. A given cell produces a sharp event at a fixed phase during the sniff cycle in response to a given…

Neurons and Cognition · Quantitative Biology 2014-07-02 Honi Sanders , Brian Kolterman , Roman Shusterman , Dmitry Rinberg , Alexei A. Koulakov , John Lisman

Odor-based Molecular Communication (OMC) employs odor molecules to convey information, contributing to the realization of the Internet of Everything (IoE) vision. Despite this, the practical deployment of OMC systems is currently limited by…

Signal Processing · Electrical Eng. & Systems 2026-02-03 Ahmet B. Kilic , Fatih E. Bilgen , Ozgur B. Akan

Locating the source of odor in a turbulent environment - a common behavior for living organisms - is non-trivial because of the random nature of mixing. Here we analyze the statistical physics aspects of the problem and propose an efficient…

Chaotic Dynamics · Physics 2009-11-07 Eugene Balkovsky , Boris I. Shraiman

Navigation by scent is a capability in robotic systems that is rising in demand. However, current methods often suffer from ambiguities, particularly when robots misattribute odours to incorrect objects due to limitations in olfactory…

Robotics · Computer Science 2025-09-23 Kordel K. France , Ovidiu Daescu

Here we introduce the Olfactory Perception (OP) benchmark, designed to assess the capability of large language models (LLMs) to reason about smell. The benchmark contains 1,010 questions across eight task categories spanning odor…

Computation and Language · Computer Science 2026-04-02 Eftychia Makri , Nikolaos Nakis , Laura Sisson , Gigi Minsky , Leandros Tassiulas , Vahid Satarifard , Nicholas A. Christakis

Inelastic electron transfer being regarded as one of the potential mechanisms to explain the odorant recognition in the atomic-scale processes is still a matter of intense debate. Here, we propose multiphonon processes of electrons transfer…

Biological Physics · Physics 2021-08-02 Shu-Quan Zhang , Yu Cui , Xue-Wei Li , Yong Sun , Zi-Wu Wang

Distributed representations of sentences have been developed recently to represent their meaning as real-valued vectors. However, it is not clear how much information such representations retain about the polarity of sentences. To study…

Computation and Language · Computer Science 2017-09-07 Edoardo Maria Ponti , Ivan Vulić , Anna Korhonen

We use the power density spectra obtained by fluctuation-enhanced sensing of bacterial odors (Escherichia coli and Anthrax-surrogate Bacillus subtilis) to generate new, highly distinguishable, types of patterns based on the average slope of…

General Physics · Physics 2012-02-20 Hung-Chih Chang , Laszlo B. Kish , Maria D. King , Chiman Kwan

Neuromorphic computing is one of the few current approaches that have the potential to significantly reduce power consumption in Machine Learning and Artificial Intelligence. Imam & Cleland presented an odour-learning algorithm that runs on…

Neural and Evolutionary Computing · Computer Science 2023-09-22 Nik Dennler , André van Schaik , Michael Schmuker

In this paper, we propose a novel concept for engineered molecular communication (MC) systems inspired by animal olfaction. We focus on a multi-user scenario where several transmitters wish to communicate with a central receiver. We assume…

Information Theory · Computer Science 2022-03-09 Vahid Jamali , Helene M. Loos , Andrea Buettner , Robert Schober , H. Vincent Poor

The problem of locating an odor source in turbulent flows is central to key applications such as environmental monitoring and disaster response. We address this challenge by designing an algorithm based on Bayesian inference, which uses…

Fluid Dynamics · Physics 2025-04-11 Lorenzo Piro , Robin A. Heinonen , Massimo Cencini , Luca Biferale

Finding the distant source of an odor dispersed by a turbulent flow is a vital task for many organisms, either for foraging or for mating purposes. At the level of individual search, animals like moths have developed effective strategies to…

Biological Physics · Physics 2020-07-15 Mihir Durve , Lorenzo Piro , Massimo Cencini , Luca Biferale , Antonio Celani

The application of deep learning techniques on aroma-chemicals has resulted in models more accurate than human experts at predicting olfactory qualities. However, public research in this domain has been limited to predicting the qualities…

Machine Learning · Computer Science 2024-06-06 Laura Sisson , Aryan Amit Barsainyan , Mrityunjay Sharma , Ritesh Kumar

The olfactory system is constantly solving pattern-recognition problems by the creation of a large space to codify odour representations and optimizing their distribution within it. A model of the Olfactory Bulb was developed by Z. Li and…

Adaptation and Self-Organizing Systems · Physics 2019-05-16 Alexandra Pinto

Early classification of time-series data in a dynamic environment is a challenging problem of great importance in signal processing. This paper proposes a classifier architecture with a reject option capable of online decision making…

Computer Vision and Pattern Recognition · Computer Science 2013-12-17 Nima Hatami , Camelia Chira

During the past few years the development of experimental techniques has allowed the quantitative analysis of biological systems ranging from neurobiology and molecular biology. This work focuses on the quantitative description of these…

Biomolecules · Quantitative Biology 2011-09-19 Carlo Barbieri