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Conformal prediction provides a principled framework for constructing predictive sets with finite-sample validity. While much of the focus has been on univariate response variables, existing multivariate methods either impose rigid…

Machine Learning · Statistics 2026-03-19 Sacha Braun , Liviu Aolaritei , Michael I. Jordan , Francis Bach

Beta regression is used routinely for continuous proportional data, but it often encounters practical issues such as a lack of robustness to misspecification of the beta distribution and sensitivity to outliers. We develop an improved class…

Methodology · Statistics 2025-10-07 Changwoo J. Lee , Benjamin K. Dahl , Otso Ovaskainen , David B. Dunson

There has been a growing acknowledgement of the involvement of the gut microbiome - the collection of microbes that reside in our gut - in regulating our mood and behaviour. This phenomenon is referred to as the microbiome-gut-brain axis.…

Genomics · Quantitative Biology 2023-12-11 Thomaz F. S. Bastiaanssen , Thomas P. Quinn , Amy Loughman

In this paper, we propose a Spatial Robust Mixture Regression model to investigate the relationship between a response variable and a set of explanatory variables over the spatial domain, assuming that the relationships may exhibit complex…

Methodology · Statistics 2021-09-30 Wennan Chang , Pengtao Dang , Changlin Wan , Xiaoyu Lu , Yue Fang , Tong Zhao , Yong Zang , Bo Li , Chi Zhang , Sha Cao

Machine learning algorithms such as linear regression, SVM and neural network have played an increasingly important role in the process of scientific discovery. However, none of them is both interpretable and accurate on nonlinear datasets.…

Quantitative Methods · Quantitative Biology 2017-10-31 Chengyu Liu , Wei Wang

Convex composition optimization is an emerging topic that covers a wide range of applications arising from stochastic optimal control, reinforcement learning and multi-stage stochastic programming. Existing algorithms suffer from…

Optimization and Control · Mathematics 2020-09-01 Tianyi Lin , Chenyou Fan , Mengdi Wang , Michael I. Jordan

Researchers are often interested in understanding the relationship between a set of covariates and a set of response variables. To achieve this goal, the use of regression analysis, either linear or generalized linear models, is largely…

In human microbiome studies, sequencing reads data are often summarized as counts of bacterial taxa at various taxonomic levels specified by a taxonomic tree. This paper considers the problem of analyzing two repeated measurements of…

Applications · Statistics 2017-02-17 Pixu Shi , Hongzhe Li

This paper introduces a rectified and renormalized Fisher-Bingham model for compositional data with zeros, motivated in part by the presence of zeros in microbiota studies. The approach represents compositions through a square-root…

Methodology · Statistics 2026-04-29 Eugene Han , Marahi Perez-Tamayo , Hannah D. Holscher , Ruoqing Zhu

Causal modeling has long been an attractive topic for many researchers and in recent decades there has seen a surge in theoretical development and discovery algorithms. Generally discovery algorithms can be divided into two approaches:…

Machine Learning · Statistics 2017-02-06 Ridho Rahmadi , Perry Groot , Marianne Heins , Hans Knoop , Tom Heskes

Unobserved confounding is one of the main challenges when estimating causal effects. We propose a causal reduction method that, given a causal model, replaces an arbitrary number of possibly high-dimensional latent confounders with a single…

Machine Learning · Statistics 2023-02-24 Maximilian Ilse , Patrick Forré , Max Welling , Joris M. Mooij

Concerning bivariate least squares linear regression, the classical results obtained for extreme structural models in earlier attempts are reviewed using a new formalism in terms of deviation (matrix) traces which, for homoscedastic data,…

Instrumentation and Methods for Astrophysics · Physics 2017-11-17 R. Caimmi

Composites, or linear combinations of variables, play an important role in multivariate behavioral research. They appear in the form of indices, inventories, formative constructs, parcels, and emergent variables. Although structural…

Methodology · Statistics 2025-09-03 Jörg Henseler , Xi Yu , Tamara Schamberger , Gregory R. Hancock , Florian Schuberth

The interactions between microbial taxa in microbiome data has been under great research interest in the science community. In particular, several methods such as SPIEC-EASI, gCoda, and CD-trace have been proposed to model the conditional…

Methodology · Statistics 2022-07-05 Chuan Tian , Duo Jiang , Yuan Jiang

High-dimensional mixed data as a combination of both continuous and ordinal variables are widely seen in many research areas such as genomic studies and survey data analysis. Estimating the underlying correlation among mixed data is hence…

Methodology · Statistics 2018-09-18 Xiaoyun Quan , James G. Booth , Martin T. Wells

Understanding covariate-varying interdependencies among features is of great interest in various applications. Motivated by microbiome studies where microbial abundances and interactions vary with environmental factors, we develop a…

Methodology · Statistics 2026-03-16 Shuangjie Zhang , Michael L. Patnode , Juhee Lee

Microbial ecosystems are remarkably diverse, stable, and often consist of a balanced mixture of core and peripheral species. Here we propose a conceptual model exhibiting all these emergent properties in quantitative agreement with real…

Populations and Evolution · Quantitative Biology 2018-04-18 Akshit Goyal , Sergei Maslov

While there are many well-developed data science methods for classification and regression, there are relatively few methods for working with right-censored data. Here, we present "survival stacking": a method for casting survival analysis…

Methodology · Statistics 2021-07-29 Erin Craig , Chenyang Zhong , Robert Tibshirani

In tasks like semantic parsing, instruction following, and question answering, standard deep networks fail to generalize compositionally from small datasets. Many existing approaches overcome this limitation with model architectures that…

Computation and Language · Computer Science 2023-07-06 Ekin Akyürek , Jacob Andreas

We consider the problem of learning the causal MAG of a system from observational data in the presence of latent variables and selection bias. Constraint-based methods are one of the main approaches for solving this problem, but the…

Machine Learning · Computer Science 2021-10-26 Sina Akbari , Ehsan Mokhtarian , AmirEmad Ghassami , Negar Kiyavash
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