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Random forests are powerful non-parametric regression method but are severely limited in their usage in the presence of randomly censored observations, and naively applied can exhibit poor predictive performance due to the incurred biases.…

Machine Learning · Statistics 2020-01-13 Alexander Hanbo Li , Jelena Bradic

Correlated survival data are prevalent in various clinical settings and have been extensively discussed in literature. One of the most common types of correlated survival data is clustered survival data, where the survival times from…

Methodology · Statistics 2024-08-02 Chengqian Xian , Camila P. E. de Souza , Wenqing He , Felipe F. Rodrigues , Renfang Tian

Research into the classification of time series has made enormous progress in the last decade. The UCR time series archive has played a significant role in challenging and guiding the development of new learners for time series…

We propose a restricted win probability estimand for comparing treatments in a randomized trial with a time-to-event outcome. We also propose Bayesian estimators for this summary measure as well as the unrestricted win probability. Bayesian…

Methodology · Statistics 2024-11-06 Michelle Leeberg , Xianghua Luo , Thomas A. Murray

Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine…

Machine Learning · Statistics 2019-08-13 Hrayr Harutyunyan , Hrant Khachatrian , David C. Kale , Greg Ver Steeg , Aram Galstyan

The intensive care units (ICUs) are responsible for generating a wealth of useful data in the form of Electronic Health Record (EHR). This data allows for the development of a prediction tool with perfect knowledge backing. We aimed to…

Machine Learning · Computer Science 2020-07-28 Saumil Maheshwari , Rohit Verma , Anupam Shukla , Ritu Tiwari , Rishu Garg

We propose a method to quantify uncertainty around individual survival distribution estimates using right-censored data, compatible with any survival model. Unlike classical confidence intervals, the survival bands produced by this method…

Methodology · Statistics 2025-12-18 Matteo Sesia , Vladimir Svetnik

Background: Incidence of adverse outcome events rises as patients with advanced illness approach end-of-life. Exposures that tend to occur near end-of-life, e.g., use of wheelchair, oxygen therapy and palliative care, may therefore be found…

Event time models predict occurrence times of an event of interest based on known features. Recent work has demonstrated that neural networks achieve state-of-the-art event time predictions in a variety of settings. However, standard event…

Machine Learning · Statistics 2020-04-06 Matthew Engelhard , Samuel Berchuck , Joshua D'Arcy , Ricardo Henao

Post-discharge care management coordinates patients' referrals to improve their health after being discharged from hospitals, especially elderly and chronically ill patients. In a care management setting, health referrals are processed by a…

Machine Learning · Computer Science 2022-06-28 Mohammed Mahyoub

Multi-omics data, that is, datasets containing different types of high-dimensional molecular variables (often in addition to classical clinical variables), are increasingly generated for the investigation of various diseases. Nevertheless,…

Machine Learning · Statistics 2020-12-22 Moritz Herrmann , Philipp Probst , Roman Hornung , Vindi Jurinovic , Anne-Laure Boulesteix

Estimating the effects of interventions on patient outcome is one of the key aspects of personalized medicine. Their inference is often challenged by the fact that the training data comprises only the outcome for the administered treatment,…

To use historical controls for indirect comparison with single-arm trials, the population difference between data sources should be adjusted to reduce confounding bias. The adjustment is more difficult for time-to-event data with a cure…

Methodology · Statistics 2023-08-23 Jixian Wang , Hongtao Zhang , Ram Tiwari

Random forests are powerful non-parametric regression method but are severely limited in their usage in the presence of randomly censored observations, and naively applied can exhibit poor predictive performance due to the incurred biases.…

Machine Learning · Statistics 2019-02-12 Alexander Hanbo Li , Jelena Bradic

Research on emergency and mass casualty incident (MCI) triage has been limited by the absence of openly usable, reproducible benchmarks. Yet these scenarios demand rapid identification of the patients most in need, where accurate…

Machine Learning · Computer Science 2026-03-31 Joshua Sebastian , Karma Tobden , KMA Solaiman

We study rare-event simulation for a class of problems where the target hitting sets of interest are defined via modern machine learning tools such as neural networks and random forests. This problem is motivated from fast emerging studies…

Machine Learning · Computer Science 2020-10-13 Yuanlu Bai , Zhiyuan Huang , Henry Lam , Ding Zhao

Information-theoretic quantities, such as conditional entropy and mutual information, are critical data summaries for quantifying uncertainty. Current widely used approaches for computing such quantities rely on nearest neighbor methods and…

Electronic medical reports (EHR) contain a vast amount of information that can be leveraged for machine learning applications in healthcare. However, existing survival analysis methods often struggle to effectively handle the complexity of…

Computation and Language · Computer Science 2025-08-01 Paul Minchella , Loïc Verlingue , Stéphane Chrétien , Rémi Vaucher , Guillaume Metzler

Risk prediction is central to both clinical medicine and public health. While many machine learning models have been developed to predict mortality, they are rarely applied in the clinical literature, where classification tasks typically…

Machine Learning · Statistics 2017-12-05 Maggie Makar , Marzyeh Ghassemi , David Cutler , Ziad Obermeyer

We present a conformal inference method for constructing lower prediction bounds for survival times from right-censored data, extending recent approaches designed for more restrictive type-I censoring scenarios. The proposed method imputes…

Methodology · Statistics 2025-05-26 Matteo Sesia , Vladimir Svetnik
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