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Related papers: Active Fingering Instability in Tissue Spreading

200 papers

In this study, thin elastic films supported on a rigid substrate are brought into contact with a spherical glass indenter. Upon contact, adhesive fingers emerge at the periphery of the contact patch with a characteristic wavelength. Elastic…

Soft Condensed Matter · Physics 2018-04-02 Benjamin Davis-Purcell , Pierre Soulard , Thomas Salez , Elie Raphael , Kari Dalnoki-Veress

The hydrodynamic theory of active nematics has been often used to describe the spatio-temporal dynamics of cell flows and motile topological defects within soft confluent tissues. Those theories, however, often rely on the assumption that…

Soft Condensed Matter · Physics 2023-08-15 Ioannis Hadjifrangiskou , Liam J. Ruske , Julia M. Yeomans

Cell extrusion is an essential mechanism for controlling cell density in epithelial tissues. Another essential element of epithelia is curvature, which is required to achieve complex shapes, like in the lung or intestine. Here we introduce…

We report on an experimental study of the Faraday instability in a vibrated fluid layer situated over a permeable and rough substrate, consisting either of a flat solid plate or of woven meshes having different openings and wire diameters,…

Active cell-junction remodeling is important for tissue morphogenesis, yet its underlying physics is not understood. We study a mechanical model that describes junctions as dynamic active force dipoles. Their instability can trigger cell…

Soft Condensed Matter · Physics 2021-11-17 Matej Krajnc , Tomer Stern , Clement Zankoc

Front propagation in two dimensional steady and unsteady cellular flows is investigated in the limit of very fast reaction and sharp front, i.e., in the geometrical optics limit. In the steady case, by means of a simplified model, we…

Pattern Formation and Solitons · Physics 2009-11-07 M. Cencini , A. Torcini , D. Vergni , A. Vulpiani

We revisit here the stability of a deformable interface that separates a fully-developed turbulent gas flow from a thin layer of laminar liquid. Unlike previous work, the turbulent base state velocity profile proposed here requires only a…

Fluid Dynamics · Physics 2016-11-26 Lennon Ó Náraigh , Peter Spelt , Omar Matar , Tamer Zaki

How can a collection of motile cells, each generating contractile nematic stresses in isolation, become an extensile nematic at the tissue-level? Understanding this seemingly contradictory experimental observation, which occurs irrespective…

Soft Condensed Matter · Physics 2022-02-21 Andrew Killeen , Thibault Bertrand , Chiu Fan Lee

We propose a simple mathematical model to describe the mechanical relaxation of cells within a curved epithelial tissue layer represented by an arbitrary curve in two-dimensional space. This model generalises previous one-dimensional models…

Cellular Automata and Lattice Gases · Physics 2025-01-09 Pascal R. Buenzli , Shahak Kuba , Ryan J. Murphy , Matthew J. Simpson

A non-modal linear stability analysis (NMA) of the miscible viscous fingering in a porous medium is studied for a toy model of non-monotonic viscosity variation. The onset of instability and its physical mechanism are captured in terms of…

Fluid Dynamics · Physics 2018-11-14 Tapan Kumar Hota , Manoranjan Mishra

Instabilities of fluid-fluid interfaces are ubiquitous in passive soft matter. Adding activity to the interface or either fluid can dramatically change the stability of the interface. Using experiment and theory, we investigate the…

Soft Condensed Matter · Physics 2026-02-04 Bennett C. Sessa , Federico Cao , Robert A. Pelcovits , Thomas R. Powers , Guillaume Duclos

Several meters below the coastal ocean surface there are areas of high ecological activity that contain thin layers of concentrated motile phytoplankton. Gyrotactic trapping has been proposed as a potential mechanism for layer formation of…

Fluid Dynamics · Physics 2019-05-22 Smitha Maretvadakethope , Eric E. Keaveny , Yongyun Hwang

The evolution of an instability at the interface of active and passive media is considered. An asymptotic form of a collision integral is found and the limitations of hydrodynamic approach are determined. A growth increment of small…

Plasma Physics · Physics 2013-12-23 Sergey Kuratov , Andrey Mikulin

In processes such as embryo shaping, wound healing, and malignant cell invasion, epithelial cells transition between dispersed phases, where the cells move independently, and condensed phases, where they aggregate and deform to close gaps,…

Soft Condensed Matter · Physics 2024-09-25 Anshuman Pasupalak , Zeng Wu , Massimo Pica Ciamarra

The linear stability of miscible displacement for radial source flow at infinite P\'eclet number in a Hele-Shaw cell is calculated theoretically. The axisymmetric self-similar flow is shown to be unstable to viscous fingering if the…

Fluid Dynamics · Physics 2025-04-09 John R. Lister , Tim-Frederik Dauck

Thin liquid films with floating active protein machines are considered. Cyclic mechanical motions within the machines, representing microscopic swimmers, lead to molecular propulsion forces applied to the air-liquid interface. We show that,…

Pattern Formation and Solitons · Physics 2015-05-13 Sergio Alonso , Alexander S. Mikhailov

This work investigates the morphological stability of a soft body composed of two heavy elastic layers, attached to a rigid surface and subjected only to the bulk gravity force. Using theoretical and computational tools, we characterize the…

Soft Condensed Matter · Physics 2017-09-21 Davide Riccobelli , Pasquale Ciarletta

We investigate the behavior of drainage displacements in heterogeneous porous media finding a transition from viscous fingering to foam-like region. A pore network model incorporating the formation of blobs is adopted to study this…

Soft Condensed Matter · Physics 2023-07-26 Federico Lanza , Santanu Sinha , Alex Hansen , Alberto Rosso , Laurent Talon

The finger-like branching pattern that occurs when a less viscous fluid displaces a more viscous one confined between two parallel plates has been widely studied as a classical example of a mathematically-tractable hydrodynamic instability…

Soft Condensed Matter · Physics 2007-12-13 Xiang Cheng , Lei Xu , Aaron Patterson , Heinrich M. Jaeger , Sidney R. Nagel

The complex behaviour of air-liquid interfaces driven into Hele-Shaw channels at high speeds could arise from oscillatory dynamics; yet, both the physical and dynamical mechanisms that lead to interfacial oscillations remain unclear. We…

Fluid Dynamics · Physics 2025-06-03 Jack Lawless , Andrew L. Hazel , Anne Juel