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Accurate and efficient cell detection is crucial in many biomedical image analysis tasks. We evaluate the performance of several Deep Learning (DL) methods for cell detection in Papanicolaou-stained cytological Whole Slide Images (WSIs),…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Marco Acerbis , Nataša Sladoje , Joakim Lindblad

Contrastive learning has been proved to be a promising technique for image-level representation learning from unlabeled data. Many existing works have demonstrated improved results by applying contrastive learning in classification and…

Image and Video Processing · Electrical Eng. & Systems 2021-09-20 Dewen Zeng , John N. Kheir , Peng Zeng , Yiyu Shi

Quantitative lung measures derived from computed tomography (CT) have been demonstrated to improve prognostication in coronavirus disease (COVID-19) patients, but are not part of the clinical routine since required manual segmentation of…

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li

The Convolutional Neural Network (CNN) has shown impressive performance in image classification because of its strong learning capabilities. However, it demands a substantial and balanced dataset for effective training. Otherwise, networks…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Arun Kunwar , Dibakar Raj Pant , Jukka Heikkonen , Rajeev Kanth

Causal discovery is becoming a key part in medical AI research. These methods can enhance healthcare by identifying causal links between biomarkers, demographics, treatments and outcomes. They can aid medical professionals in choosing more…

The advancement of computer-aided detection systems had a significant impact on clinical analysis and decision-making on human disease. Lung cancer requires more attention among the numerous diseases being examined because it affects both…

Image and Video Processing · Electrical Eng. & Systems 2023-05-24 Jafar Abdollahi

Deep learning has shown promising results in medical image analysis, however, the lack of very large annotated datasets confines its full potential. Although transfer learning with ImageNet pre-trained classification models can alleviate…

Computer Vision and Pattern Recognition · Computer Science 2018-08-16 Ken C. L. Wong , Tanveer Syeda-Mahmood , Mehdi Moradi

Computer-aided breast cancer diagnosis in mammography is limited by inadequate data and the similarity between benign and cancerous masses. To address this, we propose a signed graph regularized deep neural network with adversarial…

Image and Video Processing · Electrical Eng. & Systems 2019-09-17 Heyi Li , Dongdong Chen , William H. Nailon , Mike E. Davies , David I. Laurenson

Lung tumors, especially those located close to or surrounded by soft tissues like the mediastinum, are difficult to segment due to the low soft tissue contrast on computed tomography images. Magnetic resonance images contain superior…

Image and Video Processing · Electrical Eng. & Systems 2019-09-11 Jue Jiang , Jason Hu , Neelam Tyagi , Andreas Rimner , Sean L. Berry , Joseph O. Deasy , Harini Veeraraghavan

Recent years have witnessed a growing academic and industrial interest in deep learning (DL) for medical imaging. To perform well, DL models require very large labeled datasets. However, most medical imaging datasets are small, with a…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Minh H. Vu , Lorenzo Tronchin , Tufve Nyholm , Tommy Löfstedt

Reliably detecting diseases using relevant biological information is crucial for real-world applicability of deep learning techniques in medical imaging. We debias deep learning models during training against unknown bias - without…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Simon Langer , Oliver Taubmann , Felix Denzinger , Andreas Maier , Alexander Mühlberg

Lung cancer is one of the most deadly diseases in the world. Detecting such tumors at an early stage can be a tedious task. Existing deep learning architecture for lung nodule identification used complex architecture with large number of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Shah B. Shrey , Lukman Hakim , Muthusubash Kavitha , Hae Won Kim , Takio Kurita

Non-small cell lung cancer (NSCLC) is a serious disease and has a high recurrence rate after the surgery. Recently, many machine learning methods have been proposed for recurrence prediction. The methods using gene data have high prediction…

Computer Vision and Pattern Recognition · Computer Science 2021-04-30 Panyanat Aonpong , Yutaro Iwamoto , Xian-Hua Han , Lanfen Lin , Yen-Wei Chen

The widespread adoption of CT has notably increased the number of detected lung nodules. However, current deep learning methods for classifying benign and malignant nodules often fail to comprehensively integrate global and local features,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Zhenchen Zhu , Ge Hu , Weixiong Tan , Kai Gao , Chao Sun , Zhen Zhou , Kepei Xu , Wei Han , Meixia Shang , Xiaoming Qiu , Yiqing Tan , Jinhua Wang , Zhoumeng Ying , Li Peng , Wei Song , Lan Song , Zhengyu Jin , Nan Hong , Yizhou Yu

Rationale and objectives: Several studies have evaluated the usefulness of deep learning for lung segmentation using chest x-ray (CXR) images with small- or medium-sized abnormal findings. Here, we built a database including both CXR images…

Image and Video Processing · Electrical Eng. & Systems 2021-03-09 Mizuho Nishio , Koji Fujimoto , Kaori Togashi

Visually scoring lung involvement in systemic sclerosis from CT scans plays an important role in monitoring progression, but its labor intensiveness hinders practical application. We proposed, therefore, an automatic scoring framework that…

Image and Video Processing · Electrical Eng. & Systems 2021-10-18 Jingnan Jia , Marius Staring , Irene Hernández-Girón , Lucia J. M. Kroft , Anne A. Schouffoer , Berend C. Stoel

Computer aided diagnostic (CAD) system is crucial for modern med-ical imaging. But almost all CAD systems operate on reconstructed images, which were optimized for radiologists. Computer vision can capture features that is subtle to human…

Computer Vision and Pattern Recognition · Computer Science 2018-10-04 Dufan Wu , Kyungsang Kim , Bin Dong , Georges El Fakhri , Quanzheng Li

Traditional machine learning algorithms using hand-crafted feature extraction techniques (such as local binary pattern) have limited accuracy because of high variation in images of the same class (or intra-class variation) for food…

Computer Vision and Pattern Recognition · Computer Science 2018-12-27 Bappaditya Mandal , N. B. Puhan , Avijit Verma

Annual low dose computed tomography (CT) lung screening is currently advised for individuals at high risk of lung cancer (e.g., heavy smokers between 55 and 80 years old). The recommended screening practice significantly reduces all-cause…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Riqiang Gao , Lingfeng Li , Yucheng Tang , Sanja L. Antic , Alexis B. Paulson , Yuankai Huo , Kim L. Sandler , Pierre P. Massion , Bennett A. Landman