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Related papers: A Fully-Automatic Framework for Parkinson's Diseas…

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Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Parkinson's Disease (PD) is a degenerative neurological disorder that impairs motor and non-motor functions, significantly reducing quality of life and increasing mortality risk. Early and accurate detection of PD progression is vital for…

Machine Learning · Computer Science 2024-12-31 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza , Abhishek Sharma

Parkinson's disease (PD) presents a growing global challenge, affecting over 10 million individuals, with prevalence expected to double by 2040. Early diagnosis remains difficult due to the late emergence of motor symptoms and limitations…

Machine Learning · Computer Science 2025-10-21 Arianna Francesconi , Donato Cappetta , Fabio Rebecchi , Paolo Soda , Valerio Guarrasi , Rosa Sicilia

Early detection of Parkinson's disease (PD) is important which can enable early initiation of therapeutic interventions and management strategies. However, methods for early detection still remain an unmet clinical need in PD. In this…

Applications · Statistics 2018-10-04 R Prashanth , Sumantra Dutta Roy

Parkinson's disease (PD) has been found to affect 1 out of every 1000 people, being more inclined towards the population above 60 years. Leveraging wearable-systems to find accurate biomarkers for diagnosis has become the need of the hour,…

Machine Learning · Computer Science 2023-04-20 Poojaa C , John Sahaya Rani Alex

Accurate diagnosis of Parkinson's disease (PD) from MRI remains challenging due to symptom variability and pathological heterogeneity. Most existing methods rely on conventional magnitude-based MRI modalities, such as T1-weighted images…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Rui Jin , Chen Chen , Yin Liu , Hongfu Sun , Min Zeng , Min Li , Yang Gao

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

Quantitative Methods · Quantitative Biology 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

Parkinsons disease (PD) is a debilitating motor system disorder characterized by progressive loss of movement, tremors, and speech slurring. PD is due to the loss of dopamine-producing brain cells, and symptoms only worsen over time, making…

Neurons and Cognition · Quantitative Biology 2014-05-07 Pooja Chandrashekar

Parkinson's disease (PD) is a chronic neurodegenerative disease. It shows multiple motor symptoms such as tremor, bradykinesia, postural instability, freezing of gait (FoG). PD is currently diagnosed clinically through physical exam by…

Machine Learning · Computer Science 2026-04-21 Meheru Zannat

Parkinson's Disease (PD) is a progressive neurodegenerative disorder that significantly impacts both motor and non-motor functions, including speech. Early and accurate recognition of PD through speech analysis can greatly enhance patient…

Numerical Analysis · Mathematics 2024-07-24 Niloofar Fadavi , Nazanin Fadavi

In this work, the issue of Parkinson's disease (PD) diagnostics using non-invasive antemortem techniques was tackled. A deep learning approach for classification of raw speech recordings in patients with diagnosed PD was proposed. The core…

Computation and Language · Computer Science 2022-04-28 Maurycy Chronowski , Maciej Klaczynski , Malgorzata Dec-Cwiek , Karolina Porebska

Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…

Machine Learning · Computer Science 2022-10-05 Paria Ghaheri , Hamid Nasiri , Ahmadreza Shateri , Arman Homafar

In recent years, there are many research cases for the diagnosis of Parkinson's disease (PD) with the brain magnetic resonance imaging (MRI) by utilizing the traditional unsupervised machine learning methods and the supervised deep learning…

Image and Video Processing · Electrical Eng. & Systems 2020-03-11 Xiaobo Zhang , Donghai Zhai , Yan Yang , Yiling Zhang , Chunlin Wang

Parkinson disease (PD) is marked by progressive neurodegeneration, yet early and subtle structural alterations in brain tissue remain difficult to detect with conventional imaging and analytical methods. Fractal and multifractal frameworks…

Medical Physics · Physics 2025-12-09 Santanu Maity , Mousa Alrubayan , Mohammad Moshahid Khan , Prabhakar Pradhan

In recent years, sensors from smart consumer devices have shown great diagnostic potential in movement disorders. In this context, data modalities such as electronic questionnaires, hand movement and voice captures have successfully…

Machine Learning · Computer Science 2022-05-13 Catharina Marie van Alen , Alexander Brenner , Tobias Warnecke , Julian Varghese

Parkinson's disease (PD) is a progressive degenerative disorder of the central nervous system characterized by motor and non-motor symptoms. As the disease progresses, patients alternate periods in which motor symptoms are mitigated due to…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-26 Anna Pompili , Rubén Solera-Ureña , Alberto Abad , Rita Cardoso , Isabel Guimarães , Margherita Fabbri , Isabel P. Martins , Joaquim Ferreira

Alzheimer's Disease (AD) is the most common form of dementia and often difficult to diagnose due to the multifactorial etiology of dementia. Recent works on neuroimaging-based computer-aided diagnosis with deep neural networks (DNNs) showed…

Image and Video Processing · Electrical Eng. & Systems 2022-07-06 Marla Narazani , Ignacio Sarasua , Sebastian Pölsterl , Aldana Lizarraga , Igor Yakushev , Christian Wachinger

Parkinson's disease (PD) is a common neurological disorder characterized by gait impairment. PD has no cure, and an impediment to developing a treatment is the lack of any accepted method to predict disease progression rate. The primary aim…

Signal Processing · Electrical Eng. & Systems 2019-11-26 Vyom Raval , Kevin P. Nguyen , Ashley Gerald , Richard B. Dewey , Albert Montillo

The assessment of Parkinson's disease (PD) poses a significant challenge as it is influenced by various factors which lead to a complex and fluctuating symptom manifestation. Thus, a frequent and objective PD assessment is highly valuable…