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Neural networks have gained importance as the machine learning models that achieve state-of-the-art performance on large-scale image classification, object detection and natural language processing tasks. In this paper, we consider noisy…

Information Theory · Computer Science 2021-02-02 Chuteng Zhou , Quntao Zhuang , Matthew Mattina , Paul N. Whatmough

Convolutional neural networks (CNNs) are effective for hyperspectral image (HSI) classification, but their 3D convolutional structures introduce high computational costs and limited generalization in few-shot scenarios. Domain shifts caused…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Anyong Qin , Chaoqi Yuan , Qiang Li , Feng Yang , Tiecheng Song , Chenqiang Gao

The Shannon Noiseless coding theorem (the data-compression principle) asserts that for an information source with an alphabet $\mathcal X=\{0,\ldots ,\ell -1\}$ and an asymptotic equipartition property, one can reduce the number of stored…

Information Theory · Computer Science 2016-04-26 Yuri Suhov , Izabella Stuhl

This thesis develops computational methods in similarity-preserving hashing, classification, and cancer genomics. Standard space partitioning-based hashing relies on Binary Search Trees (BSTs), but their exponential growth and sparsity…

Machine Learning · Computer Science 2025-08-26 Prashant Gupta

An RNA sequence is a word over an alphabet on four elements $\{A,C,G,U\}$ called bases. RNA sequences fold into secondary structures where some bases match one another while others remain unpaired. Pseudoknot-free secondary structures can…

Data Structures and Algorithms · Computer Science 2018-03-28 Édouard Bonnet , Paweł Rzążewski , Florian Sikora

Genomic copy number variation (CNV) is a large source of variation between organisms, and its consequences include phenotypic differences and genetic disorders. CNVs are commonly detected by hybridizing genomic DNA to microarrays of nucleic…

Inspired by prior work by Tian and by Cao and Xu, this paper presents an efficient computer-aided framework to characterize the fundamental limits of coded caching systems under the constraint of linear coding. The proposed framework…

Information Theory · Computer Science 2025-11-26 Niccolò Brembilla , Yinbin Ma , Pietro Belotti , Federico Malucelli , Daniela Tuninetti

Various features of the development of individual living species, including individual humans, are programmed. Is death also programmed, and if yes, how is it implemented and what can be the underlying mechanism providing the inevitability…

Chaotic Dynamics · Physics 2019-05-23 Mark Edelman

Whereas Shannon entropy is related to the growth rate of multinomial coefficients, we show that the quadratic entropy (Tsallis 2-entropy) is connected to their $q$-deformation; when $q$ is a prime power, these $q$-multinomial coefficients…

Mathematical Physics · Physics 2020-03-27 Juan Pablo Vigneaux

This work presents and analyzes three convolutional neural network (CNN) models for efficient pixelwise classification of images. When using convolutional neural networks to classify single pixels in patches of a whole image, a lot of…

Computer Vision and Pattern Recognition · Computer Science 2015-09-14 Fabian Tschopp

We introduce a new protocol for a lossy data compression algorithm which is based on constraint satisfaction gates. We show that the theoretical capacity of algorithms built from standard parity-check gates converges exponentially fast to…

Disordered Systems and Neural Networks · Physics 2009-11-11 S. Ciliberti , M. Mezard , R. Zecchina

Inferring dependence structure through undirected graphs is crucial for uncovering the major modes of multivariate interaction among high-dimensional genomic markers that are potentially associated with cancer. Traditionally, conditional…

Methodology · Statistics 2016-04-04 Anindya Bhadra , Arvind Rao , Veerabhadran Baladandayuthapani

We present the discovery of a fundamental composition law governing conjugate observables in the Random Permutation Sorting System (RPSS). The law links the discrete permutation count Np and the continuous elapsed time T through a…

Cryptography and Security · Computer Science 2025-10-10 Yurang R. Kuang

Persistent homology (PH) is an approach to topological data analysis (TDA) that computes multi-scale topologically invariant properties of high-dimensional data that are robust to noise. While PH has revealed useful patterns across various…

Machine Learning · Computer Science 2021-03-23 Manu Aggarwal , Vipul Periwal

Proteins encode diverse functions within complex three-dimensional structures, yet most deep learning representations remain highly entangled, obscuring the biophysical signals that underlie function. Here we introduce ProtDiS, a…

Biomolecules · Quantitative Biology 2026-05-26 Mingqing Wang , Zhiwei Nie , Athanasios V. Vasilakos , Yonghong He , Zhixiang Ren

The article represents a new class of hidden symmetries in long sequences of oligonucleotides of single stranded DNA from their representative set. These symmetries are an addition to symmetries described by the second parity rule of…

Other Quantitative Biology · Quantitative Biology 2020-05-26 Sergey Petoukhov

In this work, we propose a structure-preserving discretisation for the recently studied Cahn-Hilliard-Biot system using conforming finite elements in space and problem-adapted explicit-implicit Euler time integration. We prove that the…

Numerical Analysis · Mathematics 2024-07-18 Aaron Brunk , Marvin Fritz

Motivation: Researchers need a rich trove of genomic datasets that they can leverage to gain a better understanding of the genetic basis of the human genome and identify associations between phenotypes and specific parts of DNA. However,…

Cryptography and Security · Computer Science 2021-06-10 Nour Almadhoun Alserr , Gulce Kale , Onur Mutlu , Oznur Tastan , Erman Ayday

By considering the basis-covariant constituents of N-Higgs-doublet potentials, we derive necessary and sufficient conditions for canonical SO(4)_C Custodial Symmetry (CS) of potentials with N>2 doublets, based on representation-theoretical…

High Energy Physics - Phenomenology · Physics 2024-11-04 R. Plantey , M. Aa. Solberg

In physics we often use very simple models to describe systems with many degrees of freedom, but it is not clear why or how this success can be transferred to the more complex biological context. We consider models for the joint…

Neurons and Cognition · Quantitative Biology 2024-12-06 Luisa Ramirez , William Bialek , Stephanie E. Palmer , David J. Schwab