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Accurate quantum chemical calculations are critical for understanding molecular properties, yet their computational cost remains a major challenge. Full Configuration Interaction (FCI) provides exact solutions but is prohibitively expensive…

Quantum Physics · Physics 2026-03-09 Fumihiko Aiga , Hayato Goto

Realizing large-scale quantum advantage is expected to require quantum error correction (QEC), making the compilation and optimization of logical operations a critical area of research. Logical computation imposes distinct constraints and…

We present a quantum CISC compiler and show how to assemble complex instruction sets in a scalable way. Enlarging the toolbox of universal gates by optimised complex multi-qubit instruction sets thus paves the way to fight decoherence for…

Quantum Physics · Physics 2008-12-22 T. Schulte-Herbrueggen , A. Spoerl , S. J. Glaser

Quantum-selected configuration interaction (QSCI) has emerged as a feasible approach for approximating electronic ground states on noisy quantum devices toward large-system demonstrations. In QSCI, Slater determinants are sampled from a…

Quantum Physics · Physics 2026-04-14 Ryota Kemmoku , Qi Gao , Shu Kanno , Kimberlee Keithley , Ikko Hamamura , Naoki Yamamoto , Kouhei Nakaji

Selected configuration interaction (sCI) methods including second-order perturbative corrections provide near full CI (FCI) quality energies with only a small fraction of the determinants of the FCI space. Here, we introduce both a…

Chemical Physics · Physics 2018-08-09 Yann Garniron , Anthony Scemama , Emmanuel Giner , Michel Caffarel , Pierre-François Loos

Computational chemistry is the leading application to demonstrate the advantage of quantum computing in the near term. However, large-scale simulation of chemical systems on quantum computers is currently hindered due to a mismatch between…

Quantum Physics · Physics 2021-05-18 Gushu Li , Yunong Shi , Ali Javadi-Abhari

Exploiting the properties of quantum information to the benefit of machine learning models is perhaps the most active field of research in quantum computation. This interest has supported the development of a multitude of software…

Quantum Physics · Physics 2023-10-24 Francesco Di Marcantonio , Massimiliano Incudini , Davide Tezza , Michele Grossi

This paper presents a comprehensive software stack architecture for integrating quantum computing (QC) capabilities with High-Performance Computing (HPC) environments. While quantum computers show promise as specialized accelerators for…

With the potential of quantum algorithms to solve intractable classical problems, quantum computing is rapidly evolving and more algorithms are being developed and optimized. Expressing these quantum algorithms using a high-level language…

Quantum Physics · Physics 2020-05-28 N. Khammassi , I. Ashraf , J. v. Someren , R. Nane , A. M. Krol , M. A. Rol , L. Lao , K. Bertels , C. G. Almudever

Quantum computers are increasingly powerful. Software tools for the development of quantum-enhanced algorithms are maturing. However, the software stack still lacks the connection to applications that would enable hybrid algorithms…

Quantum Physics · Physics 2026-05-19 Benedikt Poggel , Lena Tokuhiro , Georg Kruse , Jeanette Miriam Lorenz

Quantum Selected Configuration Interaction (QSCI) methods (also known as Sample-based Quantum Diagonalization, SQD) have emerged as promising near-term approaches to solving the electronic Schr{\"o}dinger equation with quantum computers. In…

Quantum-selected configuration interaction (QSCI) is an approach for quantum chemical calculations using current quantum computers. In conventional QSCI, Slater determinants used for the wave function expansion are sampled by iteratively…

Quantum Physics · Physics 2025-10-03 Kenji Sugisaki , Shu Kanno , Toshinari Itoko , Rei Sakuma , Naoki Yamamoto

Constraint programming (CP) is a paradigm used to model and solve constraint satisfaction and combinatorial optimization problems. In CP, problems are modeled with constraints that describe acceptable solutions and solved with backtracking…

Quantum Physics · Physics 2021-09-29 Kyle E. C. Booth , Bryan O'Gorman , Jeffrey Marshall , Stuart Hadfield , Eleanor Rieffel

The accurate description of electron correlation is a central challenge in computational chemistry, with selected configuration interaction (SCI) emerging as a powerful tool to approach the full CI limit. While recent machine learning (ML)…

Chemical Physics · Physics 2026-05-12 Wan Nie , Songwei Liu , Yingying Yu , Zhiwen Wang , and Jun Yang

With the birth of Noisy Intermediate Scale Quantum (NISQ) devices and the verification of "quantum supremacy" in random number sampling and boson sampling, more and more fields hope to use quantum computers to solve specific problems, such…

Programming Languages · Computer Science 2023-01-02 Menghan Dou , Tianrui Zou , Yuan Fang , Jing Wang , Dongyi Zhao , Lei Yu , Boying Chen , Wenbo Guo , Ye Li , Zhaoyun Chen , Guoping Guo

Quantum centric supercomputing (QCSC) framework, such as sample-based quantum diagonalization (SQD) holds immense promise toward achieving practical quantum utility to solve challenging problems. QCSC leverages quantum computers to perform…

The goal of this paper is to deliver the overview of the current state of the art, to provide experience report on developing quantum software tools, and to outline the perspective for developing quantum programming tools supporting…

Quantum Physics · Physics 2023-09-14 Jarosław Adam Miszczak

Quilc is an open-source, optimizing compiler for gate-based quantum programs written in Quil or QASM, two popular quantum programming languages. The compiler was designed with attention toward NISQ-era quantum computers, specifically…

Quantum Physics · Physics 2020-04-01 Robert S. Smith , Eric C. Peterson , Mark G. Skilbeck , Erik J. Davis

Quantum computers are appealing for their ability to solve some tasks much faster than their classical counterparts. It was shown in [Aspuru-Guzik et al., Science 309, 1704 (2005)] that they, if available, would be able to perform the full…

Quantum Physics · Physics 2010-11-19 Libor Veis , Jiří Pittner