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Image reconstruction in low-count PET is particularly challenging because gammas from natural radioactivity in Lu-based crystals cause high random fractions that lower the measurement signal-to-noise-ratio (SNR). In model-based image…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Hongki Lim , Il Yong Chun , Yuni K. Dewaraja , Jeffrey A. Fessler

Online reconstruction based on RGB-D sequences has thus far been restrained to relatively slow camera motions (<1m/s). Under very fast camera motion (e.g., 3m/s), the reconstruction can easily crumble even for the state-of-the-art methods.…

Computer Vision and Pattern Recognition · Computer Science 2021-05-13 Jiazhao Zhang , Chenyang Zhu , Lintao Zheng , Kai Xu

Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…

The day we understand the time evolution of subcellular elements at a level of detail comparable to physical systems governed by Newton's laws of motion seems far away. Even so, quantitative approaches to cellular dynamics add to our…

Advances in optical and electrophysiological recording technologies have made it possible to record the dynamics of thousands of neurons, opening up new possibilities for interpreting and controlling large neural populations in behaving…

Neurons and Cognition · Quantitative Biology 2023-11-20 Fatih Dinc , Adam Shai , Mark Schnitzer , Hidenori Tanaka

Tracking of plant cells in images obtained by microscope is a challenging problem due to biological phenomena such as large number of cells, non-uniform growth of different layers of the tightly packed plant cells and cell division.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Md Shazid Islam , Arindam Dutta , Calvin-Khang Ta , Kevin Rodriguez , Christian Michael , Mark Alber , G. Venugopala Reddy , Amit K. Roy-Chowdhury

Whole-body Positron Emission Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Xiangcen Wu , Ruohua Chen , Sichun Li , Qianye Yang , Sheng Liu , Jianjun Liu , Zhaoheng Xie

Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Jieqing Jiao , Sebastien Ourselin

Patlak model is widely used in 18F-FDG dynamic positron emission tomography (PET) imaging, where the estimated parametric images reveal important biochemical and physiology information. Because of better noise modeling and more information…

Medical Physics · Physics 2020-09-15 Nuobei Xie , Kuang Gong , Ning Guo , Zhixing Qin , Jianan Cui , Zhifang Wu , Huafeng Liu , Quanzheng Li

The present paper proposes a novel computational method for parametric imaging of nuclear medicine data. The mathematical procedure is general enough to work for compartmental models of diverse complexity and is effective in the…

Tissues and Organs · Quantitative Biology 2017-05-15 Mara Scussolini , Sara Garbarino , Gianmario Sambuceti , Giacomo Caviglia , Michele Piana

Image reconstruction for positron emission tomography (PET) is challenging because of the ill-conditioned tomographic problem and low counting statistics. Kernel methods address this challenge by using kernel representation to incorporate…

Image and Video Processing · Electrical Eng. & Systems 2022-05-26 Siqi Li , Guobao Wang

Conventional cell tracking methods detect multiple cells in each frame (detection) and then associate the detection results in successive time-frames (association). Most cell tracking methods perform the association task independently from…

Computer Vision and Pattern Recognition · Computer Science 2020-02-27 Junya Hayashida , Kazuya Nishimura , Ryoma Bise

Medical image reconstruction from measurement data is a vital but challenging inverse problem. Deep learning approaches have achieved promising results, but often requires paired measurement and high-quality images, which is typically…

Image and Video Processing · Electrical Eng. & Systems 2025-11-19 Taoran Zheng , Yan Yang , Xing Li , Xiang Gu , Jian Sun , Zongben Xu

We introduce a method for fast estimation of data-adapted, spatio-temporally dependent regularization parameter-maps for variational image reconstruction, focusing on total variation (TV)-minimization. Our approach is inspired by recent…

Deep learning based PET image reconstruction methods have achieved promising results recently. However, most of these methods follow a supervised learning paradigm, which rely heavily on the availability of high-quality training labels. In…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Rui Hu , Yunmei Chen , Kyungsang Kim , Marcio Aloisio Bezerra Cavalcanti Rockenbach , Quanzheng Li , Huafeng Liu

Dynamic positron emission tomography (dPET) image reconstruction is extremely challenging due to the limited counts received in individual frame. In this paper, we propose a spatial-temporal convolutional primal dual network (STPDnet) for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Rui Hu , Jianan Cui , Chengjin Yu , Yunmei Chen , Huafeng Liu

In the context of dynamic emission tomography, the conventional processing pipeline consists of independent image reconstruction of single time frames, followed by the application of a suitable kinetic model to time activity curves (TACs)…

Applications · Statistics 2018-08-28 Michele Scipioni , Stefano Pedemonte , Maria Filomena Santarelli , Luigi Landini

Our aim was to enhance visual quality and quantitative accuracy of dynamic positron emission tomography (PET)uptake images by improved image reconstruction, using sophisticated sparse penalty models that incorporate both 2D spatial+1D…

Computer Vision and Pattern Recognition · Computer Science 2019-06-17 Ida Häggström , Yizun Lin , Si Li , Andrzej Krol , Yuesheng Xu , C. Ross Schmidtlein

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

Positron emission tomography (PET) is a cornerstone of modern radiology. The ability to detect cancer and metastases in whole body scans fundamentally changed cancer diagnosis and treatment. One of the main bottlenecks in the clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Ida Häggström , C. Ross Schmidtlein , Gabriele Campanella , Thomas J. Fuchs