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Planar homography estimation is foundational to many computer vision problems, such as Simultaneous Localization and Mapping (SLAM) and Augmented Reality (AR). However, conditions of high variance confound even the state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2020-10-23 David Niblick , Avinash Kak

The Convolutional Neural Networks (CNNs) have emerged as a very powerful data dependent hierarchical feature extraction method. It is widely used in several computer vision problems. The CNNs learn the important visual features from…

Computer Vision and Pattern Recognition · Computer Science 2021-01-01 Jayendra Kantipudi , Shiv Ram Dubey , Soumendu Chakraborty

The rapid growth of digital pathology in recent years has provided an ideal opportunity for the development of artificial intelligence-based tools to improve the accuracy and efficiency of clinical diagnoses. One of the significant…

Image and Video Processing · Electrical Eng. & Systems 2024-03-08 Jack Breen , Kieran Zucker , Katie Allen , Nishant Ravikumar , Nicolas M. Orsi

While human observers are able to cope with variations in color and appearance of histological stains, digital pathology algorithms commonly require a well-normalized setting to achieve peak performance, especially when a limited amount of…

Computer Vision and Pattern Recognition · Computer Science 2017-08-15 Daniel Bug , Steffen Schneider , Anne Grote , Eva Oswald , Friedrich Feuerhake , Julia Schüler , Dorit Merhof

Noise injection is a fundamental tool for data augmentation, and yet there is no widely accepted procedure to incorporate it with learning frameworks. This study analyzes the effects of adding or applying different noise models of varying…

Computer Vision and Pattern Recognition · Computer Science 2023-07-14 M. Eren Akbiyik

For proper generalization performance of convolutional neural networks (CNNs) in medical image segmentation, the learnt features should be invariant under particular non-linear shape variations of the input. To induce invariance in CNNs to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-10 Mauricio Orbes Arteaga , Lauge Sørensen , M. Jorge Cardoso , Marc Modat , Sebastien Ourselin , Stefan Sommer , Mads Nielsen , Christian Igel , Akshay Pai

Convolutional Neural Networks (CNNs) have become the state-of-the-art method to learn from image data. However, recent research shows that they may include a texture and colour bias in their representation, contrary to the intuition that…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Francis Brochu

Deep learning advances have revolutionized automated digital pathology analysis. However, differences in staining protocols and imaging conditions can introduce significant color variability. In deep learning, such color inconsistency often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Tianyue Xu , Yanlin Wu , Abhai K. Tripathi , Matthew M. Ippolito , Benjamin D. Haeffele

In practice, digital pathology images are often affected by various factors, resulting in very large differences in color and brightness. Stain normalization can effectively reduce the differences in color and brightness of digital…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Hongtao Kang , Die Luo , Li Chen , Junbo Hu , Tingwei Quan , Shaoqun Zeng , Shenghua Cheng , Xiuli Liu

In recent years, Classical Convolutional Neural Networks (CNNs) have been applied for image recognition successfully. Quantum Convolutional Neural Networks (QCNNs) are proposed as a novel generalization to CNNs by using quantum mechanisms.…

Quantum Physics · Physics 2023-12-04 Leting Zhouli , Peiyong Wang , Udaya Parampalli

Hematoxylin and Eosin (H&E) has been the gold standard in tissue analysis for decades, however, tissue specimens stained in different laboratories vary, often significantly, in appearance. This variation poses a challenge for both…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Umair Khan , Jouni Härkönen , Marjukka Friman , Leena Latonen , Teijo Kuopio , Pekka Ruusuvuori

The color appearance of a pathological image is highly related to the imaging protocols, the proportion of different dyes, and the scanning devices. Computer-aided diagnostic systems may deteriorate when facing these color-variant…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Zheng Chen

Convolutional Neural Networks (CNNs) for visual tasks are believed to learn both the low-level textures and high-level object attributes, throughout the network depth. This paper further investigates the `texture bias' in CNNs. To this end,…

Computer Vision and Pattern Recognition · Computer Science 2021-10-22 Amin Banitalebi-Dehkordi , Yong Zhang

We quantify the generalization of a convolutional neural network (CNN) trained to identify cars. First, we perform a series of experiments to train the network using one image dataset - either synthetic or from a camera - and then test on a…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Zhenyi Liu , Trisha Lian , Joyce Farrell , Brian Wandell

Stain normalization often refers to transferring the color distribution of the source image to that of the target image and has been widely used in biomedical image analysis. The conventional stain normalization is regarded as constructing…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Hongtao Kang , Die Luo , Weihua Feng , Junbo Hu , Shaoqun Zeng , Tingwei Quan , Xiuli Liu

Digitized Histological diagnosis is in increasing demand. However, color variations due to various factors are imposing obstacles to the diagnosis process. The problem of stain color variations is a well-defined problem with many proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 M Tarek Shaban , Christoph Baur , Nassir Navab , Shadi Albarqouni

The different stain styles of cytopathological images have a negative effect on the generalization ability of automated image analysis algorithms. This article proposes a new framework that normalizes the stain style for cytopathological…

Image and Video Processing · Electrical Eng. & Systems 2019-09-12 Xihao Chen , Jingya Yu , Li Chen , Shaoqun Zeng , Xiuli Liu , Shenghua Cheng

Differences in staining and imaging procedures can cause significant color variations in histopathology images, leading to poor generalization when deploying deep-learning models trained from a different data source. Various color…

Dermoscopic skin images are often obtained with different imaging devices, under varying acquisition conditions. In this work, instead of attempting to perform intensity and color normalization, we propose to leverage computational color…

The application of supervised deep learning methods in digital pathology is limited due to their sensitivity to domain shift. Digital Pathology is an area prone to high variability due to many sources, including the common practice of…

Image and Video Processing · Electrical Eng. & Systems 2020-12-24 Jelica Vasiljević , Friedrich Feuerhake , Cédric Wemmert , Thomas Lampert