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The Filament Based Lamellipodium Model (FBLM) is a two-phase two-dimensional continuum model, describing the dynamcis of two interacting families of locally parallel actin filaments (C.Schmeiser and D.Oelz, How do cells move? Mathematical…

Cell Behavior · Quantitative Biology 2015-02-10 Angelika Manhart , Christian Schmeiser , Nikolaos Sfakianakis , Dietmar Oelz

The self-assembly of proteins into $\beta$-sheet-rich amyloid fibrils has been observed to occur with sigmoidal kinetics, indicating that the system initially is trapped in a metastable state. Here, we use a minimal lattice-based model to…

Biological Physics · Physics 2016-01-05 Anders Irbäck , Jonas Wessén

Understanding how growth induces form is a longstanding biological question. Many studies concentrated on the shapes of plant cells, fungi or bacteria. Some others have shown the importance of the mechanical properties of bacterial walls…

Biological Physics · Physics 2007-05-23 Arezki Boudaoud

We use numerical simulations of turbulent cluster-forming regions to study the nature of dense filamentary structures in star formation. Using four hydrodynamic and magnetohydrodynamic simulations chosen to match observations, we identify…

Astrophysics of Galaxies · Physics 2015-06-23 Helen Kirk , Ralph Pudritz , Mikhail Klassen , Samantha Pillsworth

Filaments are an ubiquitous feature of molecular clouds, and appear to play a critical role in assembling the material to form stars. The dominant filaments are observed to have a rather narrow range of widths around $\sim 0.1$ pc, and to…

Astrophysics of Galaxies · Physics 2022-03-14 F. D. Priestley , A. P. Whitworth

The cytoskeleton is an active composite of filamentous proteins that dictates diverse mechanical properties and processes in eukaryotic cells by generating forces and autonomously restructuring itself. Enzymatic motors that act on the…

While semi-flexible polymers and fibers are an important class of material due to their rich mechanical properties, it remains unclear how these properties relate to the microscopic conformation of the polymers. Actin filaments constitute…

The paper addresses the underlying source of two forms of induced anisotropy in granular materials: contact orientation anisotropy and contact force anisotropy. A rational, mathematical structure is reviewed for the manner in which fabric…

Soft Condensed Matter · Physics 2019-01-23 Matthew R. Kuhn

The biopolymers actin and microtubules are often in an ongoing assembling/disassembling state far from thermal equilibrium. Above a critical density this leads to spatially periodic patterns, as shown by a scaling argument and in terms of a…

Soft Condensed Matter · Physics 2007-05-23 Falko Ziebert , Walter Zimmermann

Contractile forces are essential for many developmental processes involving cell shape change and tissue deformation. Recent experiments on reconstituted actomyosin networks, the major component of the contractile machinery, have shown that…

Biological Physics · Physics 2012-05-31 Shenshen Wang , Peter G. Wolynes

The formation of bundles composed of actin filaments and cross-linking proteins is an essential process in the maintenance of the cells' cytoskeleton. It has also been recreated by in-vitro experiments, where actin networks are routinely…

Soft Condensed Matter · Physics 2009-11-13 Nir S. Gov

Actin is a key component of the cytoskeleton, which plays central roles in cell motility, division, growth, and tensile strength. To enable this wide range of transient mechanical processes and properties, networks of actin filaments…

Recent numerical works, including ours, lend credence to the thesis that ambient environment, i.e., external pressure, affects star-forming ability of clouds & filaments. In continuation with our series of papers on the subject we explore…

Astrophysics of Galaxies · Physics 2024-09-17 S. V. Anathpindika , J. Di Francesco

The occurrence of coiled or helical morphologies is common in nature, from plant roots to DNA packaging into viral capsids, as well as in applications such as oil drilling processes. In many examples, chiral structures result from the…

We probed the bending of actin subject to external forcing and viscous drag. Single actin filaments were moved perpendicular to their long axis in an oscillatory way by means of an optically tweezed latex bead attached to one end of the…

Soft Condensed Matter · Physics 2009-10-30 D. Riveline , Chris H. Wiggins , A. Ott , Raymond E. Goldstein

An overview of the related topics of anomalous coarsening and glassy dynamics is given. In anomalous coarsening, the typical domain size of an ordered phase grows more slowly with time than the power law dependence that is usually observed,…

Statistical Mechanics · Physics 2009-11-07 M. R. Evans

Advances in synthetic biology allow us to engineer bacterial collectives with pre-specified characteristics. However, the behavior of these collectives is difficult to understand, as cellular growth and division as well as extra-cellular…

Cell Behavior · Quantitative Biology 2017-09-13 James J. Winkle , Oleg Igoshin , Matthew R. Bennett , Krešimir Josić , William Ott

Many biological processes involve the action of molecular motors that interact with the cell cytoskeleton. Some processes, such as the transport of cargoes is achieved mainly by the action of individual motors. Other, such as cell motility…

Biological Physics · Physics 2011-03-25 Oded Farago , Anne Bernheim-Groswasser

The three-dimensional microstructure of Ni, observed after five annealing intervals, was compared to simulations of grain growth using the threshold dynamics method with the assumption of capillarity as the only driving force. A…

Large-scale force generation is essential for biological functions such as cell motility, embryonic development, and muscle contraction. In these processes, forces generated at the molecular level by motor proteins are transmitted by…

Soft Condensed Matter · Physics 2016-04-05 Pierre Ronceray , Chase Broedersz , Martin Lenz