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Due to the continuously improving capabilities of mobile edges, recommender systems start to deploy models on edges to alleviate network congestion caused by frequent mobile requests. Several studies have leveraged the proximity of…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-18 Kairui Fu , Shengyu Zhang , Zheqi Lv , Jingyuan Chen , Jiwei Li

Neoplasms (NPs) and neurological diseases and disorders (NDDs) are amongst the major classes of diseases underlying deaths of a disproportionate number of people worldwide. To determine if there exist some distinctive features in the local…

Molecular Networks · Quantitative Biology 2022-12-27 Vikram Singh , Vikram Singh

We design a self size-estimating feed-forward network (SSFN) using a joint optimization approach for estimation of number of layers, number of nodes and learning of weight matrices. The learning algorithm has a low computational complexity,…

Machine Learning · Computer Science 2020-03-06 Saikat Chatterjee , Alireza M. Javid , Mostafa Sadeghi , Shumpei Kikuta , Dong Liu , Partha P. Mitra , Mikael Skoglund

Edge detection with Artificial Neural Networks (ANNs) has achieved remarkable prog\-ress but faces two major challenges. First, it requires pre-training on large-scale extra data and complex designs for prior knowledge, leading to high…

Neural and Evolutionary Computing · Computer Science 2025-11-19 Yimeng Fan , Changsong Liu , Mingyang Li , Yuzhou Dai , Yanyan Liu , Wei Zhang

In general, deep neural network (DNN) pruning methods fall into two categories: 1) Weight-based deterministic constraints, and 2) Probabilistic frameworks. While each approach has its merits and limitations there are a set of common…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Madan Ravi Ganesh , Dawsin Blanchard , Jason J. Corso , Salimeh Yasaei Sekeh

One of the main challenges in modeling massive stars to the onset of core collapse is the computational bottleneck of nucleosynthesis during advanced burning stages. The number of isotopes formed requires solving a large set of…

The deployment of deep convolutional neural networks (CNNs) in many real world applications is largely hindered by their high computational cost. In this paper, we propose a novel learning scheme for CNNs to simultaneously 1) reduce the…

Computer Vision and Pattern Recognition · Computer Science 2017-08-23 Zhuang Liu , Jianguo Li , Zhiqiang Shen , Gao Huang , Shoumeng Yan , Changshui Zhang

We report on atomistic simulation of the folding of a natively-knotted protein, MJ0366, based on a realistic force field. To the best of our knowledge this is the first reported effort where a realistic force field is used to investigate…

Biomolecules · Quantitative Biology 2013-02-11 Silvio a Beccara , Tatjana Skrbic , Roberto Covino , Cristian Micheletti , Pietro Faccioli

Neural network optimization remains one of the most consequential yet poorly understood challenges in modern AI research, where improvements in training algorithms can lead to enhanced feature learning in foundation models,…

Machine Learning · Computer Science 2025-12-23 Ansh Nagwekar

The brain is a highly reconfigurable machine capable of task-specific adaptations. The brain continually rewires itself for a more optimal configuration to solve problems. We propose a novel strategic synthesis algorithm for feedforward…

Artificial Intelligence · Computer Science 2021-04-22 Alastair Finlinson , Sotiris Moschoyiannis

The increasing demand on precision and throughput within high-precision mechatronics industries requires a new generation of feedforward controllers with higher accuracy than existing, physics-based feedforward controllers. As neural…

Systems and Control · Electrical Eng. & Systems 2024-01-26 Max Bolderman , Hans Butler , Sjirk Koekebakker , Eelco van Horssen , Ramidin Kamidi , Theresa Spaan-Burke , Nard Strijbosch , Mircea Lazar

We view the folding of RNA-sequences as a map that assigns a pattern of base pairings to each sequence, known as secondary structure. These preimages can be constructed as random graphs (i.e. the neutral networks associated to the structure…

adap-org · Physics 2008-02-03 Christian V. Forst , Christian Reidys , Jacqueline Weber

Prediction of protein secondary structure from the amino acid sequence is a classical bioinformatics problem. Common methods use feed forward neural networks or SVMs combined with a sliding window, as these models does not naturally handle…

Quantitative Methods · Quantitative Biology 2015-01-06 Søren Kaae Sønderby , Ole Winther

Initial protein structural comparisons were sequence-based. Since amino acids that are distant in the sequence can be close in the 3-dimensional (3D) structure, 3D contact approaches can complement sequence approaches. Traditional 3D…

Molecular Networks · Quantitative Biology 2017-03-01 Fazle E. Faisal , Julie L. Chaney , Khalique Newaz , Jun Li , Scott J. Emrich , Patricia L. Clark , Tijana Milenkovic

In this paper we experiment with using neural network structures to predict a protein's secondary structure ({\alpha} helix positions) from only its primary structure (amino acid sequence). We implement a fully connected neural network…

Machine Learning · Computer Science 2022-08-25 Sidharth Malhotra , Robin Walters

We propose a general method for predicting potentially good folders from a given number of amino acid sequences. Our approach is based on the calculation of the rate of convergence of each amino acid chain towards the native structure using…

Biological Physics · Physics 2013-02-07 Dmitry K. Gridnev , Pedro Ojeda-May , Martin E. Garcia

Large Artificial Neural Network (ANN) models have demonstrated success in various domains, including general text and image generation, drug discovery, and protein-RNA (ribonucleic acid) binding tasks. However, these models typically demand…

Biomolecules · Quantitative Biology 2025-11-13 Stanislav Selitskiy

By folding into particular 3D structures, proteins play a key role in living beings. To learn meaningful representation from a protein structure for downstream tasks, not only the global backbone topology but the local fine-grained…

Biomolecules · Quantitative Biology 2025-02-05 Jiahan Li , Shitong Luo , Congyue Deng , Chaoran Cheng , Jiaqi Guan , Leonidas Guibas , Jian Peng , Jianzhu Ma

Deep spiking neural networks (SNNs) have emerged as a potential alternative to traditional deep learning frameworks, due to their promise to provide increased compute efficiency on event-driven neuromorphic hardware. However, to perform…

Neural and Evolutionary Computing · Computer Science 2021-07-28 Souvik Kundu , Gourav Datta , Massoud Pedram , Peter A. Beerel

This paper considers the network slicing (NS) problem which attempts to map multiple customized virtual network requests to a common shared network infrastructure and allocate network resources to meet diverse service requirements. This…

Information Theory · Computer Science 2024-09-26 Wei-Kun Chen , Zheyu Wu , Rui-Jin Zhang , Ya-Feng Liu , Yu-Hong Dai , Zhi-Quan Luo