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Functional Connectivity between brain regions is known to be altered in Alzheimer's disease, and promises to be a biomarker for early diagnosis of the disease. While several approaches for functional connectivity obtain an un-directed…

Neurons and Cognition · Quantitative Biology 2024-02-21 Rahul Biswas , SuryaNarayana Sripada

NMDA receptors (NMDA-R) typically contribute to excitatory synaptic transmission in the central nervous system. While calcium influx through NMDA-R plays a critical role in synaptic plasticity, experimental evidence indicates that…

Neurons and Cognition · Quantitative Biology 2020-02-03 David Gall , Geneviève Dupont

The preservation of the corticospinal tract (CST) is key to good motor recovery after stroke. The gold standard method of assessing the CST with imaging is diffusion tensor tractography. However, this is not available for most intracerebral…

Deep brain stimulation (DBS) is a neurosurgical procedure successfully used to treat conditions such as Parkinson's disease. Electrostimulation, carried out by implanting electrodes into an identified focus in the brain, makes it possible…

Signal Processing · Electrical Eng. & Systems 2023-08-23 Arkadiusz Nowacki , Ewelina Kołpa , Mateusz Szychiewicz , Konrad Ciecierski

Background: Direct electrical stimulation of the brain through intracranial electrodes is currently used to probe the epileptic brain as part of pre-surgical evaluation, and it is also being considered for therapeutic treatments through…

Neurons and Cognition · Quantitative Biology 2020-11-18 Christoforos A Papasavvas , Gabrielle M Schroeder , Beate Diehl , Gerold Baier , Peter N Taylor , Yujiang Wang

Cortical spreading depression (CSD) is a slow-moving ionic and metabolic disturbance that propagates in cortical brain tissue. In addition to massive cellular depolarization, CSD also involves significant changes in perfusion and metabolism…

Neurons and Cognition · Quantitative Biology 2020-06-05 Joshua C. Chang , K. C. Brennan , Dongdong He , Huaxiong Huang , Robert M. Miura , Phillip L. Wilson , Jonathan J. Wylie

Generative models of brain activity have been instrumental in testing hypothesized mechanisms underlying brain dynamics against experimental datasets. Beyond capturing the key mechanisms underlying spontaneous brain dynamics, these models…

Neurons and Cognition · Quantitative Biology 2024-11-18 Rishikesan Maran , Eli J. Müller , Ben D. Fulcher

Transcranial photobiomodulation (tPBM) therapy is an emerging, non-invasive neuromodulation technique that has demonstrated considerable potential in the field of neuropsychiatric disorders. Several studies have found that pulsed wave (PW)…

Neurons and Cognition · Quantitative Biology 2025-12-02 Jiangshan He , Hui Xie , Yuqiang Yang , Chunli Jia , Dan Liang , Lianghua Zhang , Xiaoyu Wang , Tianyi Luo , Zexiao Dong , Huiting Yang , Zhen Yuan , Mingzhe Jiang , Xueli Chen

Compensation is a technique to roll-back a system to a consistent state in case of failure. Recovery mechanisms for compensating calculi specify the order of execution of compensation sequences. Dynamic recovery means that the order of…

Programming Languages · Computer Science 2014-04-02 Abeer S. Al-Humaimeedy , Maribel Fernández

The possibility of explaining shear flow dynamos by a magnetic shear-current (MSC) effect is examined via numerical simulations. Our primary diagnostics is the determination of the turbulent magnetic diffusivity tensor $\boldsymbol{\eta}$.…

Background: Real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) has proven to be a powerful technique to help subjects to gauge and enhance emotional control. Traditionally, rtfMRI-nf has focused on emotional…

The reciprocal interconversion between spin polarization and charge current (CSC) is the focus of intensive theoretical and experimental investigation in spintronics research. Its physical origin stems from the Rashba spin-orbit coupling…

Mesoscale and Nanoscale Physics · Physics 2025-02-06 Gerson J. Ferreira , Boyu Wang , Jiyong Fu , Roberto Raimondi

Synaptic connections between neurons in the brain are dynamic because of continuously ongoing spine dynamics, axonal sprouting, and other processes. In fact, it was recently shown that the spontaneous synapse-autonomous component of spine…

Neurons and Cognition · Quantitative Biology 2018-01-08 David Kappel , Robert Legenstein , Stefan Habenschuss , Michael Hsieh , Wolfgang Maass

Robot-assisted Transcranial Magnetic Stimulation (Robo-TMS) is an image-guided robotic intervention that enhances the accuracy and reproducibility of conventional Transcranial Magnetic Stimulation (TMS), a widely used non-invasive brain…

Robotics · Computer Science 2026-04-29 Wenzhi Bai , Yituo Guo , Bhaskar Basu , Andrew Weightman , Zhenhong Li

Models of the cortico-basal ganglia network and volume conductor models of the brain can provide insight into the mechanisms of action of deep brain stimulation (DBS). In this study, the coupling of a network model, under parkinsonian…

Neurons and Cognition · Quantitative Biology 2017-05-31 Christian Schmidt , Eleanor Dunn , Madeleine Lowery , Ursula van Rienen

Objective: Evaluate the feasibility and potential impacts on hand function using a wearable stimulation device (the VTS Glove) which provides mechanical, vibratory input to the affected limb of chronic stroke survivors. Methods: A…

Human-Computer Interaction · Computer Science 2022-08-02 Caitlyn E. Seim , Steven L. Wolf , Thad E. Starner

The presence of diffuse Focal Axonal Swellings (FAS) is a hallmark cellular feature in many neurodegenerative diseases and traumatic brain injury. Among other things, the FAS have a significant impact on spike-train encodings that propagate…

Neurons and Cognition · Quantitative Biology 2016-08-23 Pedro D. Maia , J. Nathan Kutz

Causal inference in brain networks has traditionally relied on regression-based models such as Granger causality, structural equation modeling, and dynamic causal modeling. While effective for identifying directed associations, these…

Neurons and Cognition · Quantitative Biology 2026-04-01 Moo K. Chung , Luigi Maccotta , Aaron Struck

Neurodegenerative diseases and traumatic brain injuries (TBI) are among the main causes of cognitive dysfunction in humans. Both manifestations exhibit the extensive presence of focal axonal swellings (FAS). FAS compromises the information…

Neurons and Cognition · Quantitative Biology 2016-09-27 Melanie Weber , Pedro D. Maia , J. Nathan Kutz

Experimental results of rectification of a constant wave radio frequency (RF) current flowing in a single-layered ferromagnetic wire are presented. We show that a detailed external magnetic field dependence of the RF current induced a…

Mesoscale and Nanoscale Physics · Physics 2007-10-12 A. Yamaguchi , K. Motoi , H. Miyajima , Y. Nakatani
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