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Phylodynamics seeks to estimate effective population size fluctuations from molecular sequences of individuals sampled from a population of interest. One way to accomplish this task formulates an observed sequence data likelihood exploiting…

A variety of methods have been proposed for interpreting nodes in deep neural networks, which typically involve scoring nodes at lower layers with respect to their effects on the output of higher-layer nodes (where lower and higher layers…

Machine Learning · Computer Science 2018-12-04 Jonathan Warrell , Hussein Mohsen , Mark Gerstein

Many fundamental statistical methods have become critical tools for scientific data analysis yet do not scale tractably to modern large datasets. This paper will describe very recent algorithms based on computational geometry which have…

The standard approach to estimate species trees is to align a selected set of genes, concatenate the alignments and then estimate a consensus tree. However, individual genes contain differing levels of evolutionary information, either…

Populations and Evolution · Quantitative Biology 2021-11-29 Ali Amiryousefi

In population genetics, extant samples are usually used for inference of past population genetic forces. With the Kingman coalescent and the backward diffusion equation, inference of the marginal likelihood proceeds from an extant sample…

Populations and Evolution · Quantitative Biology 2020-04-03 Claus Vogl , Sandra Peer

The density estimation is one of the core problems in statistics. Despite this, existing techniques like maximum likelihood estimation are computationally inefficient due to the intractability of the normalizing constant. For this reason an…

Machine Learning · Computer Science 2021-01-14 Tsimboy Olga , Yermek Kapushev , Evgeny Burnaev , Ivan Oseledets

As the amount and complexity of available data increases, the need for robust statistical learning becomes more pressing. To enhance resilience against model misspecification, the generalized posterior inference method adjusts the…

Computation · Statistics 2024-09-04 Masahiro Tanaka

We propose and implement a method to analyze time series with a neural network using a matrix of area-normalized persistence landscapes obtained through topological data analysis. We include a gating layer in the network's architecture that…

Machine Learning · Computer Science 2023-02-08 Aina Ferrà , Carles Casacuberta , Oriol Pujol

In recent years, sequential importance sampling (SIS) has been well developed for sampling contingency tables with linear constraints. In this paper, we apply SIS procedure to 2-dimensional Ising models, which give observations of 0-1…

Computation · Statistics 2014-10-17 Jing Xi , Seth Sullivant

One of the most striking findings in modern research on large language models (LLMs) is that scaling up compute during training leads to better results. However, less attention has been given to the benefits of scaling compute during…

Computation and Language · Computer Science 2024-11-21 Sean Welleck , Amanda Bertsch , Matthew Finlayson , Hailey Schoelkopf , Alex Xie , Graham Neubig , Ilia Kulikov , Zaid Harchaoui

We propose a nonparametric procedure to achieve fast inference in generative graphical models when the number of latent states is very large. The approach is based on iterative latent variable preselection, where we alternate between…

Machine Learning · Statistics 2021-10-06 Jacquelyn A. Shelton , Jan Gasthaus , Zhenwen Dai , Joerg Luecke , Arthur Gretton

Cluster analysis has proved to be an invaluable tool for the exploratory and unsupervised analysis of high dimensional datasets. Among methods for clustering, hierarchical approaches have enjoyed substantial popularity in genomics and other…

Methodology · Statistics 2014-11-20 Patrick K. Kimes , Yufeng Liu , D. Neil Hayes , J. S. Marron

We introduce a new Bayesian model for hierarchical clustering based on a prior over trees called Kingman's coalescent. We develop novel greedy and sequential Monte Carlo inferences which operate in a bottom-up agglomerative fashion. We show…

Machine Learning · Statistics 2009-07-07 Yee Whye Teh , Hal Daumé , Daniel Roy

We present an algorithm for learning decision trees using stochastic gradient information as the source of supervision. In contrast to previous approaches to gradient-based tree learning, our method operates in the incremental learning…

Machine Learning · Statistics 2019-09-25 Henry Gouk , Bernhard Pfahringer , Eibe Frank

The emergence and development of cancer is a consequence of the accumulation over time of genomic mutations involving a specific set of genes, which provides the cancer clones with a functional selective advantage. In this work, we model…

Machine Learning · Computer Science 2017-03-10 Daniele Ramazzotti , Marco S. Nobile , Paolo Cazzaniga , Giancarlo Mauri , Marco Antoniotti

Cardinality estimation algorithms receive a stream of elements whose order might be arbitrary, with possible repetitions, and return the number of distinct elements. Such algorithms usually seek to minimize the required storage and…

Data Structures and Algorithms · Computer Science 2015-08-26 Reuven Cohen , Liran Katzir , Aviv Yehezkel

In recent decades, a number of profound theorems concerning approximation of hard counting problems have appeared. These include estimation of the permanent, estimating the volume of a convex polyhedron, and counting (approximately) the…

Data Structures and Algorithms · Computer Science 2020-09-07 Isabel Beichl , Alathea Jensen

Multiple sampling-based methods have been developed for approximating and accelerating node embedding aggregation in graph convolutional networks (GCNs) training. Among them, a layer-wise approach recursively performs importance sampling to…

Machine Learning · Computer Science 2023-06-19 Yifan Chen , Tianning Xu , Dilek Hakkani-Tur , Di Jin , Yun Yang , Ruoqing Zhu

In this paper, we consider the knot matching problem arising in computational forestry. The knot matching problem is an important problem that needs to be solved to advance the state of the art in automatic strength prediction of lumber. We…

Applications · Statistics 2017-08-28 Seong-Hwan Jun , Samuel W. K. Wong , James V. Zidek , Alexandre Bouchard-Côté

We propose and study a multi-scale approach to vector quantization. We develop an algorithm, dubbed reconstruction trees, inspired by decision trees. Here the objective is parsimonious reconstruction of unsupervised data, rather than…

Machine Learning · Computer Science 2019-09-05 Enrico Cecini , Ernesto De Vito , Lorenzo Rosasco
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