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Living cells provide a fluctuating, out-of-equilibrium environment in which genes must coordinate cellular function. DNA looping, which is a common means of regulating transcription, is very much a stochastic process; the loops arise from…

Biomolecules · Quantitative Biology 2015-05-18 Yih-Fan Chen , J. N. Milstein , Jens-Christian Meiners

The high linear charge density of 20-base-pair oligomers of DNA is shown to lead to a striking non-monotonic dependence of the long-time self-diffusion on the concentration of the DNA in low-salt conditions. This generic non-monotonic…

Soft Condensed Matter · Physics 2009-11-13 M. G. McPhie , G. Naegele

A new molecular dynamics model in which the point charges on atomic sites are allowed to fluctuate in response to the environment is developed and applied to water. The idea for treating charges as variables is based on the concept of…

chem-ph · Physics 2009-10-22 Steven W. Rick , Steven J. Stuart , B. J. Berne

The role of thermal pressure fluctuation excited within tightly packaged DNA prior to ejection from protein capsid shells is discussed in a model calculation. At equilibrium before ejection we assume the DNA is folded many times into a…

Biological Physics · Physics 2010-12-22 Michael J. Harrison

Based on our formulation of the DNA electrophoresis near a pore [P. Rowghanian and A. Y. Grosberg, Phys. Rev. E 87, 042723 (2013)], we address the electrophoretic DNA capture into a nanopore as a steady-state process of particle absorption…

Biological Physics · Physics 2013-06-20 Payam Rowghanian , Alexander Y. Grosberg

Recent works on localized charge transport along DNA, based on a three--dimensional, tight--binding model (Eur. Phys. J. B 30:211, 2002; Phys. D 180:256, 2003), suggest that charge transport is mediated by the coupling of the radial and…

Pattern Formation and Solitons · Physics 2007-05-23 F. Palmero , J. F. R. Archilla , D. Hennig , F. R. Romero

The pair interaction between two stiff parallel linear DNA molecules depends not only on the distance between their axes but on their azimuthal orientation. The positional and orientational order in columnar B-DNA assemblies in solution is…

Soft Condensed Matter · Physics 2009-11-07 H. M. Harreis , A. A. Kornyshev , C. N. Likos , H. Loewen , G. Sutmann

We generalize the predictions for attractions between over-all neutral surfaces induced by charge fluctuations/correlations to non-uniform systems that include dielectric discontinuities, as is the case for mixed charged lipid membranes in…

Soft Condensed Matter · Physics 2009-10-31 Rebecca Menes , Philip Pincus , Bean Stein

We report on our theoretical investigations of the electronic states in a DNA molecule. We have used a two-leg charge ladder model where electron-electron interactions and the electron spin have been taken into account. The energy spectra…

Disordered Systems and Neural Networks · Physics 2009-11-10 V. M. Apalkov , Tapash Chakraborty

Conceptualization, theory, method developments and implementations are always of great importance and an interesting task to explore a new dimension in science and technology, which is highly solicited for various functional-driven…

Mesoscale and Nanoscale Physics · Physics 2025-05-07 Karuppuchamy Navamani

Two models for energy and charge transport and storage in biomolecules are considered. A model based on the discrete nonlinear Schrodinger equation with long-range dispersive interactions (LRI's) between base pairs of DNA is offered for the…

Quantum transport for DNA conduction has widely studied with interest in application as a candidate in making nanowires as well as interest in the scientific mechanism. In this paper, we review recent works with concerning the electronic…

Disordered Systems and Neural Networks · Physics 2015-03-13 Hiroaki Yamada , Kazumoto Iguchi

The cage model for polymer reptation, proposed by Evans and Edwards, and its recent extension to model DNA electrophoresis, are studied by numerically exact computation of the drift velocities for polymers with a length L of up to 15…

Soft Condensed Matter · Physics 2009-11-07 A. van Heukelum , G. T. Barkema , R. H. Bisseling

We present a very simple model for the study of charge transport in a molecule patterned on B-DNA. In this model we use a discrete non-linear Schr\"{o}dinger equation to describe electrons propagating along the sugar-phosphate backbone of…

Soft Condensed Matter · Physics 2009-11-10 Niels R. Walet , Wojtek J. Zakrzewski

The thermodynamic properties of DNA circular molecules are investigated by a new path integral computational method which treats in the real space the fundamental forces stabilizing the molecule. The base pair and stacking contributions to…

Soft Condensed Matter · Physics 2014-11-11 Marco Zoli

Tuning of protein surface charge is a fundamental mechanism in biological systems. Protein charge is regulated in a physiological context by pH and interaction with counterions. We report on charge inversion and the related reentrant…

Soft Condensed Matter · Physics 2013-05-29 Felix Roosen-Runge , Benjamin S. Heck , Fajun Zhang , Oliver Kohlbacher , Frank Schreiber

The dynamics of polymer translocation through a pore has been the subject of recent theoretical and experimental works. We have considered theoretical estimates and performed computer simulations to understand the mechanism of DNA uptake…

Soft Condensed Matter · Physics 2009-11-07 Zeno Farkas , Imre Derenyi , Tamas Vicsek

A systematic study of electron or hole transfer along DNA dimers, trimers and polymers is presented with a tight-binding approach at the base-pair level, using the relevant on-site energies of the base-pairs and the hopping parameters…

Biological Physics · Physics 2014-06-30 Constantinos Simserides

Recent advances in the understanding of the melting behavior of double-stranded DNA with statistical mechanics methods lead to improved estimates of the weight factors for the dissociation events of the chains, in particular for interior…

Statistical Mechanics · Physics 2009-11-07 Ralf Blossey , Enrico Carlon

Recent experiments indicated that disorder effect in DNA may lead to a transition of the charge transport mechanism from band resonant tunnelling to thermal activated hopping. In this letter, based on Mott's variable-range hopping theory we…

Soft Condensed Matter · Physics 2013-12-16 Yong-Gang Yang , Peng-Gang Yin , Xin-Qi Li anf YiJing Yan