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Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

In the field of computational histopathology, both whole slide images (WSIs) and diagnostic captions provide valuable insights for making diagnostic decisions. However, aligning WSIs with diagnostic captions presents a significant…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Qifeng Zhou , Wenliang Zhong , Yuzhi Guo , Michael Xiao , Hehuan Ma , Junzhou Huang

Subcortical segmentation remains challenging despite its important applications in quantitative structural analysis of brain MRI scans. The most accurate method, manual segmentation, is highly labor intensive, so automated tools like…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Aaron Cao , Vishwanatha M. Rao , Kejia Liu , Xinrui Liu , Andrew F. Laine , Jia Guo

Purpose: Thyroid scintigraphy plays a vital role in diagnosing a range of thyroid disorders. While deep learning classification models hold significant promise in this domain, their effectiveness is frequently compromised by limited and…

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

3D models surpass 2D models in CT/MRI segmentation by effectively capturing inter-slice relationships. However, the added depth dimension substantially increases memory consumption. While patch-based training alleviates memory constraints,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Young Seok Jeon , Hongfei Yang , Huazhu Fu , Mengling Feng

Histopathology, the microscopic study of diseased tissue, is increasingly digitized, enabling improved visualization and streamlined workflows. An important task in histopathology is the segmentation of cells and glands, essential for…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Philipp Endres , Valentin Koch , Julia A. Schnabel , Carsten Marr

Histopathology images contain essential information for medical diagnosis and prognosis of cancerous disease. Segmentation of glands in histopathology images is a primary step for analysis and diagnosis of an unhealthy patient. Due to the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Safiyeh Rezaei , Ali Emami , Hamidreza Zarrabi , Shima Rafiei , Kayvan Najarian , Nader Karimi , Shadrokh Samavi , S. M. Reza Soroushmehr

We address the computational barrier of deploying advanced deep learning segmentation models in clinical settings by studying the efficacy of network compression through tensor decomposition. We propose a post-training Tucker factorization…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Tobias Weber , Jakob Dexl , David Rügamer , Michael Ingrisch

Weakly supervised segmentation is an important problem in medical image analysis due to the high cost of pixelwise annotation. Prior methods, while often focusing on weak labels of 2D images, exploit few structural cues of volumetric…

Computer Vision and Pattern Recognition · Computer Science 2021-05-07 Qian He , Shuailin Li , Xuming He

Computational pathology and whole-slide image (WSI) analysis are pivotal in cancer diagnosis and prognosis. However, the ultra-high resolution of WSIs presents significant modeling challenges. Recent advancements in pathology foundation…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Honglin Li , Zhongyi Shui , Yunlong Zhang , Chenglu Zhu , Lin Yang

The objective of this study was to develop an automated pipeline that enhances thyroid disease classification using thyroid scintigraphy images, aiming to decrease assessment time and increase diagnostic accuracy. Anterior thyroid…

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Digital gigapixel whole slide image (WSI) is widely used in clinical diagnosis, and automated WSI analysis is key for computer-aided diagnosis. Currently, analyzing the integrated descriptor of probabilities or feature maps from massive…

Computer Vision and Pattern Recognition · Computer Science 2022-06-06 Ziquan Wei , Shenghua Cheng , Junbo Hu , Li Chen , Shaoqun Zeng , Xiuli Liu

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang

The segmentation of kidney layer structures, including cortex, outer stripe, inner stripe, and inner medulla within human kidney whole slide images (WSI) plays an essential role in automated image analysis in renal pathology. However, the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Muhao Liu , Chenyang Qi , Shunxing Bao , Quan Liu , Ruining Deng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Hyperspectral image (HSI) classification is a crucial technique for remote sensing to build large-scale earth monitoring systems. HSI contains much more information than traditional visual images for identifying the categories of land…

Computer Vision and Pattern Recognition · Computer Science 2025-01-09 Zhiqiang Gao , Jiaqi Wang , Hangchi Shen , Zhihao Dou , Xiangbo Zhang , Kaizhu Huang

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

The current study of cell architecture of inflammation in histopathology images commonly performed for diagnosis and research purposes excludes a lot of information available on the biopsy slide. In autoimmune diseases, major outstanding…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Pranav Singh , Jacopo Cirrone
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