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Enzymes and proteins are live driven biochemicals, which has a dramatic impact over the environment, in which it is active. So, therefore, it is highly looked-for to build such a robust and highly accurate automatic and computational model…

Biomolecules · Quantitative Biology 2021-01-11 Zaheer Ullah Khan , Dechang Pi , Izhar Ahmed Khan , Asif Nawaz , Jamil Ahmad , Mushtaq Hussain

Motivation: How do we integratively analyze large-scale multi-platform genomic data that are high dimensional and sparse? Furthermore, how can we incorporate prior knowledge, such as the association between genes, in the analysis…

Machine Learning · Computer Science 2017-11-28 Dongjin Choi , Lee Sael

With the rise of Transformer models in NLP and CV domain, Multi-Head Attention has been proven to be a game-changer. However, its expensive computation poses challenges to the model throughput and efficiency, especially for the long…

Image and Video Processing · Electrical Eng. & Systems 2024-04-12 Jiing-Ping Wang , Ming-Guang Lin , An-Yeu , Wu

Single-cell RNA sequencing (scRNA-seq) is widely used to reveal heterogeneity in cells, which has given us insights into cell-cell communication, cell differentiation, and differential gene expression. However, analyzing scRNA-seq data is a…

Machine Learning · Computer Science 2023-06-27 Yuta Hozumi , Gu-Wei Wei

Shape is an important aspects in recognizing plants. Several approaches have been introduced to identify objects, including plants. Combination of geometric features such as aspect ratio, compactness, and dispersion, or moments such as…

Computer Vision and Pattern Recognition · Computer Science 2011-10-10 A. Kadir , L. E. Nugroho , A. Susanto , P. I. Santosa

Early diagnosis of plant diseases is critical for global food safety, yet most AI solutions lack the generalization required for real-world agricultural diversity. These models are typically constrained to specific species, failing to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Saif Ur Rehman Khan , Muhammad Nabeel Asim , Sebastian Vollmer , Andreas Dengel

Large Language Models (LLMs) present significant computational and memory challenges due to their extensive size, making pruning essential for their efficient deployment. Existing one-shot pruning methods often apply uniform sparsity…

Computation and Language · Computer Science 2025-10-14 Florentin Beck , William Rudman , Carsten Eickhoff

The ability to quickly and accurately identify microbial species in a sample, known as metagenomic profiling, is critical across various fields, from healthcare to environmental science. This paper introduces a novel method to profile…

Genomics · Quantitative Biology 2025-04-10 Riselda Kodra , Hadjer Benmeziane , Irem Boybat , William Andrew Simon

In unforeseen situations, such as nuclear power plant's or civilian radiation accidents, there is a need for effective and computationally inexpensive methods to determine the expression level of a selected gene panel, allowing for rough…

Genomics · Quantitative Biology 2024-12-13 Tomasz Strzoda , Lourdes Cruz-Garcia , Mustafa Najim , Christophe Badie , Joanna Polanska

A convolutional neural network (CNN) is a deep learning algorithm that has been specifically designed for computer vision applications. The CNNs proved successful in handling the increasing amount of data in many computer vision problems,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Mustafa Yurdakul , Enes Ayan , Fahrettin Horasan , Sakir Tasdemir

With the fast evolution of high-throughput technology, longitudinal gene expression experiments have become affordable and increasingly common in biomedical fields. Generalized estimating equation (GEE) approach is a widely used statistical…

Applications · Statistics 2020-08-13 Suyan Tian , Chi Wang , Mayte Suarez-Farinas

Accurate skin cancer diagnosis is vital for early treatment and improved patient outcomes. Deep learning (DL) models have shown promise in automating skin cancer classification, yet challenges remain due to data scarcity and limited…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Hamzeh Asgharnezhad , Pegah Tabarisaadi , Abbas Khosravi , Roohallah Alizadehsani , U. Rajendra Acharya

Preference learning is a widely adopted post-training technique that aligns large language models (LLMs) to human preferences and improves specific downstream task capabilities. In this work we systematically investigate how specific…

Computation and Language · Computer Science 2024-12-23 Joongwon Kim , Anirudh Goyal , Aston Zhang , Bo Xiong , Rui Hou , Melanie Kambadur , Dhruv Mahajan , Hannaneh Hajishirzi , Liang Tan

Robust local feature representations are essential for spatial intelligence tasks such as robot navigation and augmented reality. Establishing reliable correspondences requires descriptors that provide both high discriminative power and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Haodi Yao , Fenghua He , Ning Hao , Yao Su

For long-tailed classification, most works often pretrain a big model on a large-scale dataset, and then fine-tune the whole model for adapting to long-tailed data. Though promising, fine-tuning the whole pretrained model tends to suffer…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Bowen Dong , Pan Zhou , Shuicheng Yan , Wangmeng Zuo

Next-generation sequencing techniques have facilitated a large scale analysis of human genetic variation. Despite the advances in sequencing speeds, the computational discovery of structural variants is not yet standard. It is likely that…

RNA sequencing (RNA-seq) enables characterization and quantification of individual transcriptomes as well as detection of patterns of allelic expression and alternative splicing. Current RNA-seq protocols depend on high-throughput…

Genomics · Quantitative Biology 2015-06-19 Hyunghoon Cho , Joe Davis , Xin Li , Kevin S. Smith , Alexis Battle , Stephen B. Montgomery

We introduce a novel Deep Network architecture that implements the full feature point handling pipeline, that is, detection, orientation estimation, and feature description. While previous works have successfully tackled each one of these…

Computer Vision and Pattern Recognition · Computer Science 2016-08-01 Kwang Moo Yi , Eduard Trulls , Vincent Lepetit , Pascal Fua

The advent of DNA and RNA sequencing has revolutionized the study of genomics and molecular biology. Next generation sequencing (NGS) technologies like Illumina, Ion Torrent, SOLiD sequencing etc. have brought about a quick and cheap way to…

Genomics · Quantitative Biology 2021-03-26 Yun Heo , Gowthami Manikandan , Anand Ramachandran , Deming Chen

Digital Pathology is a cornerstone in the diagnosis and treatment of diseases. A key task in this field is the identification and segmentation of cells in hematoxylin and eosin-stained images. Existing methods for cell segmentation often…

Computer Vision and Pattern Recognition · Computer Science 2025-01-10 Fabian Hörst , Moritz Rempe , Helmut Becker , Lukas Heine , Julius Keyl , Jens Kleesiek