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Current computational methods for exon-intron structure prediction from a cluster of transcript (EST, mRNA) data do not exhibit the time and space efficiency necessary to process large clusters of over than 20,000 ESTs and genes longer than…

Genomics · Quantitative Biology 2010-05-11 Paola Bonizzoni , Gianluca Della Vedova , Yuri Pirola , Raffaella Rizzi

Single-cell RNA sequencing (scRNAseq) is rapidly advancing our understanding of cellular composition within complex tissues and organisms. A major limitation in most scRNAseq analysis pipelines is the reliance on manual annotations to…

Genomics · Quantitative Biology 2022-06-10 A. Ali Heydari , Oscar A. Davalos , Katrina K. Hoyer , Suzanne S. Sindi

Complementary-label learning (CLL) is a weakly supervised learning paradigm for multiclass classification, where only complementary labels -- indicating classes an instance does not belong to -- are provided to the learning algorithm.…

Machine Learning · Computer Science 2024-11-20 Nai-Xuan Ye , Tan-Ha Mai , Hsiu-Hsuan Wang , Wei-I Lin , Hsuan-Tien Lin

In machine learning systems, privileged features refer to the features that are available during offline training but inaccessible for online serving. Previous studies have recognized the importance of privileged features and explored ways…

Information Retrieval · Computer Science 2023-12-15 Xiaoqiang Gui , Yueyao Cheng , Xiang-Rong Sheng , Yunfeng Zhao , Guoxian Yu , Shuguang Han , Yuning Jiang , Jian Xu , Bo Zheng

Plant diseases pose a serious challenge to agriculture by reducing crop yield and affecting food quality. Early detection and classification of these diseases are essential for minimising losses and improving crop management practices. This…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Srinivas Kanakala , Sneha Ningappa

Predicting click-through rates (CTR) is a fundamental task for Web applications, where a key issue is to devise effective models for feature interactions. Current methodologies predominantly concentrate on modeling feature interactions…

Information Retrieval · Computer Science 2024-04-08 Yushen Li , Jinpeng Wang , Tao Dai , Jieming Zhu , Jun Yuan , Rui Zhang , Shu-Tao Xia

Motivation: Accurate detection of sequence similarity and homologous recombination are essential parts of many evolutionary analyses. Results: We have developed SimPlot++, an open-source multiplatform application implemented in Python,…

Quantitative Methods · Quantitative Biology 2022-04-14 Stéphane Samson , Étienne Lord , Vladimir Makarenkov

CLIP-seq methods are valuable techniques to experimentally determine transcriptome-wide binding sites of RNA-binding proteins. Despite the constant improvement of such techniques (e.g. eCLIP), the results are affected by various types of…

Biomolecules · Quantitative Biology 2024-12-31 Gianluca Corrado , Michael Uhl , Rolf Backofen , Andrea Passerini , Fabrizio Costa

Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the cellular level. By providing data on gene expression for each individual cell, scRNA-seq generates large datasets with thousands of…

Computational Complexity · Computer Science 2025-02-11 Md Romizul Islam , Swakkhar Shatabda

Recent studies on plant disease diagnosis using machine learning (ML) have highlighted concerns about the overestimated diagnostic performance due to inappropriate data partitioning, where training and test datasets are derived from the…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Yuji Arima , Satoshi Kagiwada , Hitoshi Iyatomi

Recent advances in deep learning have enabled significant progress in plant disease classification using leaf images. Much of the existing research in this field has relied on the PlantVillage dataset, which consists of well-centered plant…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Wassim Benabbas , Mohammed Brahimi , Samir Akhrouf , Bilal Fortas

Existing computer vision research in artwork struggles with artwork's fine-grained attributes recognition and lack of curated annotated datasets due to their costly creation. To the best of our knowledge, we are one of the first methods to…

Computer Vision and Pattern Recognition · Computer Science 2022-05-02 Marcos V. Conde , Kerem Turgutlu

Decision trees are a widely used method for classification, both by themselves and as the building blocks of multiple different ensemble learning methods. The Max-Cut decision tree involves novel modifications to a standard, baseline model…

Machine Learning · Computer Science 2020-06-26 Jonathan Bodine , Dorit S. Hochbaum

I describe our team's development of the SpeX Prism Library Analysis Toolkit (SPLAT), a combined spectral data repository for over 2500 low-resolution spectra of very low mass dwarfs (late M, L and T dwarfs), and Python-based analysis…

Solar and Stellar Astrophysics · Physics 2017-10-03 Adam J. Burgasser , the SPLAT Development Team

High throughput sequencing is a technology that allows for the generation of millions of reads of genomic data regarding a study of interest, and data from high throughput sequencing platforms are usually count compositions. Subsequent…

Quantitative Methods · Quantitative Biology 2017-04-07 Jia R. Wu , Jean M. Macklaim , Briana L. Genge , Gregory B. Gloor

Table Structure Recognition (TSR) is vital for various downstream tasks like information retrieval, table reconstruction, and document understanding. While most state-of-the-art (SOTA) research predominantly focuses on TSR in English…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Dhruv Kudale , Badri Vishal Kasuba , Venkatapathy Subramanian , Parag Chaudhuri , Ganesh Ramakrishnan

The emerging research shows that lncRNA has crucial research value in a series of complex human diseases. Therefore, the accurate identification of lncRNA-disease associations (LDAs) is very important for the warning and treatment of…

Machine Learning · Computer Science 2024-06-06 Wen-Yu Xi , Juan Wang , Yu-Lin Zhang , Jin-Xing Liu , Yin-Lian Gao

Large reasoning models (LRMs) like OpenAI-o1 and DeepSeek-R1 have demonstrated remarkable capabilities in complex reasoning tasks through the utilization of long Chain-of-thought (CoT). However, these models often suffer from hallucinations…

Computation and Language · Computer Science 2025-03-10 Chengpeng Li , Mingfeng Xue , Zhenru Zhang , Jiaxi Yang , Beichen Zhang , Xiang Wang , Bowen Yu , Binyuan Hui , Junyang Lin , Dayiheng Liu

Injecting world knowledge into pretrained multimodal large language models (MLLMs) is essential for domain-specific applications. Task-specific fine-tuning achieves this by tailoring MLLMs to high-quality in-domain data but encounters…

Multimedia · Computer Science 2026-03-31 Xiao An , Jiaxing Sun , Ting Hu , Wei He

Accurate cell type annotation across datasets is a key challenge in single-cell analysis. snRNA-seq enables profiling of frozen or difficult-to-dissociate tissues, complementing scRNA-seq by capturing fragile or rare cell types. However,…

Genomics · Quantitative Biology 2026-03-10 Xiran Chen , Quan Zou , Qinyu Cai , Xiaofeng Chen , Weikai Li , Yansu Wang
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