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Intercellular exchange networks are essential for the adaptive capabilities of populations of cells. While diffusional exchanges have traditionally been difficult to map, recent advances in nanotechnology enable precise probing of exchange…

Statistical Mechanics · Physics 2024-12-13 Luís C. F. Latoski , Andrea De Martino , Daniele De Martino

Capturing the structure of a data-generating process by means of appropriate inductive biases can help in learning models that generalize well and are robust to changes in the input distribution. While methods that harness spatial and…

Turing patterns play a fundamental role in morphogenesis and population dynamics, encoding key information about the underlying biological mechanisms. Yet, traditional inverse problems have largely relied on non-biological data such as…

Analysis of PDEs · Mathematics 2025-09-10 Yuhan Li , Hongyu Liu , Catharine W. K. Lo

In a mathematical model of interacting biological organisms, where external interventions may alter behavior over time, traditional models that assume fixed parameters usually do not capture the evolving dynamics. In oncology, this is…

Machine Learning · Computer Science 2025-12-18 Kayode Olumoyin , Lamees El Naqa , Katarzyna Rejniak

Recent genomic and bioinformatic advances have motivated the development of numerous random network models purporting to describe graphs of biological, technological, and sociological origin. The success of a model has been evaluated by how…

Molecular Networks · Quantitative Biology 2007-05-23 Manuel Middendorf , Etay Ziv , Carter Adams , Jen Hom , Robin Koytcheff , Chaya Levovitz , Gregory Woods , Linda Chen , Chris Wiggins

Deep learning applies hierarchical layers of hidden variables to construct nonlinear high dimensional predictors. Our goal is to develop and train deep learning architectures for spatio-temporal modeling. Training a deep architecture is…

Machine Learning · Statistics 2018-05-08 Matthew F. Dixon , Nicholas G. Polson , Vadim O. Sokolov

Spatial relations between neurons in the network with time delays play a crucial role in determining dynamics of the system. During the development of the nervous system different types of neurons group together to enable specific functions…

Adaptation and Self-Organizing Systems · Physics 2019-12-18 Michał Łepek , Piotr Fronczak

Social systems are in a constant state of flux with dynamics spanning from minute-by-minute changes to patterns present on the timescale of years. Accurate models of social dynamics are important for understanding spreading of influence or…

Physics and Society · Physics 2017-01-02 Vedran Sekara , Arkadiusz Stopczynski , Sune Lehmann

Sensory perception (e.g. vision) relies on a hierarchy of cortical areas, in which neural activity propagates in both directions, to convey information not only about sensory inputs but also about cognitive states, expectations and…

Neurons and Cognition · Quantitative Biology 2023-04-13 Grégory Faye , Guilhem Fouilhé , Rufin VanRullen

Originating from the pioneering study of Alan Turing, the bifurcation analysis predicting spatial pattern formation from a spatially uniform state for diffusing morphogens or chemical species that interact through nonlinear reactions is a…

Pattern Formation and Solitons · Physics 2023-01-18 Merlin Pelz , Michael J. Ward

Cells receive signaling molecules by receptors and relay information via sensory networks so that they can respond properly depending on the type of signal. Recent studies have shown that cells can extract multi-dimensional information from…

Biological Physics · Physics 2018-02-14 Yoshihiko Hasegawa

Most current methods for identifying coherent structures in spatially-extended systems rely on prior information about the form which those structures take. Here we present two new approaches to automatically filter the changing…

Cellular Automata and Lattice Gases · Physics 2011-11-09 Cosma Rohilla Shalizi , Robert Haslinger , Jean-Baptiste Rouquier , Kristina Lisa Klinkner , Cristopher Moore

By their very nature microscopy images of cells and tissues consist of a limited number of object types or components. In contrast to most natural scenes, the composition is known a priori. Decomposing biological images into semantically…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Avelino Javer , Jens Rittscher

We propose a novel discrete model of central pattern generators (CPG), neuronal ensembles generating rhythmic activity. The model emphasizes the role of nonsynaptic interactions and the diversity of electrical properties in nervous systems.…

Neural and Evolutionary Computing · Computer Science 2017-05-10 Nikolay Bazenkov , Varvara Dyakonova , Oleg Kuznetsov , Dmitri Sakharov , Dmitry Vorontsov , Liudmila Zhilyakova

Networks in nature are often formed within a spatial domain in a dynamical manner, gaining links and nodes as they develop over time. We propose a class of spatially-based growing network models and investigate the relationship between the…

Physics and Society · Physics 2013-12-30 Ari Zitin , Alex Gorowora , Shane Squires , Mark Herrera , Thomas M. Antonsen , Michelle Girvan , Edward Ott

There is no much doubt that biotic interactions shape community assembly and ultimately the spatial co-variations between species. There is a hope that the signal of these biotic interactions can be observed and retrieved by investigating…

Machine Learning · Statistics 2025-07-15 Sara Si-Moussi , Esther Galbrun , Mickael Hedde , Giovanni Poggiato , Matthias Rohr , Wilfried Thuiller

We develop a framework to track the structure of temporal networks with a signal processing approach. The method is based on the duality between networks and signals using a multidimensional scaling technique. This enables a study of the…

Social and Information Networks · Computer Science 2015-05-13 Ronan Hamon , Pierre Borgnat , Patrick Flandrin , Céline Robardet

Exchange of biochemical substances is essential way in establishing communication between bacterial cells. It is noticeable that all phases of the process are heavily influenced by perturbations of either internal or external parameters.…

Chaotic Dynamics · Physics 2010-08-18 Igor Balaz , Dragutin T. Mihailovic

Biologically inspired auditory models play an important role in developing effective audio representations that can be tightly integrated into speech and audio processing systems. Current computational models of the cochlea are typically…

Audio and Speech Processing · Electrical Eng. & Systems 2021-08-16 T. Dang , V. Sethu , E. Ambikairajah , J. Epps , H. Li

Cellular nuclei recognition serves as a fundamental and essential step in the workflow of digital pathology. However, with disparate source organs and staining procedures among histology image clusters, the scanned tiles inherently conform…

Quantitative Methods · Quantitative Biology 2024-07-22 Jianan Fan , Dongnan Liu , Canran Li , Hang Chang , Heng Huang , Filip Braet , Mei Chen , Weidong Cai