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This study focuses on the estimation of the Emax dose-response model, a widely utilized framework in clinical trials, agriculture, and environmental experiments. Existing challenges in obtaining maximum likelihood estimates (MLE) for model…

Methodology · Statistics 2025-06-11 Giacomo Aletti , Nancy Flournoy , Caterina May , Chiara Tommasi

The Rasch model, a classical model in the item response theory, is widely used in psychometrics to model the relationship between individuals' latent traits and their binary responses to assessments or questionnaires. In this paper, we…

Machine Learning · Statistics 2025-10-31 Yuepeng Yang , Cong Ma

Maximum likelihood estimation (MLE) of latent variable models is often recast as the minimization of a free energy functional over an extended space of parameters and probability distributions. This perspective was recently combined with…

Machine Learning · Computer Science 2024-06-05 Jen Ning Lim , Juan Kuntz , Samuel Power , Adam M. Johansen

We study nonparametric estimation for current status data with competing risks. Our main interest is in the nonparametric maximum likelihood estimator (MLE), and for comparison we also consider a simpler ``naive estimator.'' Groeneboom,…

Statistics Theory · Mathematics 2008-06-20 Piet Groeneboom , Marloes H. Maathuis , Jon A. Wellner

The advent of data science has spurred interest in estimating properties of distributions over large alphabets. Fundamental symmetric properties such as support size, support coverage, entropy, and proximity to uniformity, received most…

Information Theory · Computer Science 2016-11-29 Jayadev Acharya , Hirakendu Das , Alon Orlitsky , Ananda Theertha Suresh

We study the problem of maximum likelihood estimation given one data sample ($n=1$) over Brownian Motion Tree Models (BMTMs), a class of Gaussian models on trees. BMTMs are often used as a null model in phylogenetics, where the one-sample…

Maximum likelihood estimation (MLE) is a fundamental problem in statistics. Characteristics of the MLE problem for discrete algebraic statistical models are reflected in the geometry of the $\textit{likelihood correspondence}$, a variety…

Statistics Theory · Mathematics 2024-11-19 David Barnhill , John Cobb , Matthew Faust

For the univariate current status and, more generally, the interval censoring model, distribution theory has been developed for the maximum likelihood estimator (MLE) and smoothed maximum likelihood estimator (SMLE) of the unknown…

Statistics Theory · Mathematics 2013-06-18 Piet Groeneboom

We obtain explicit $p$-Wasserstein distance error bounds between the distribution of the multi-parameter MLE and the multivariate normal distribution. Our general bounds are given for possibly high-dimensional, independent and identically…

Statistics Theory · Mathematics 2021-12-28 Andreas Anastasiou , Robert E. Gaunt

This paper considers maximum likelihood (ML) estimation in a large class of models with hidden Markov regimes. We investigate consistency of the ML estimator and local asymptotic normality for the models under general conditions which allow…

Statistics Theory · Mathematics 2021-12-07 Demian Pouzo , Zacharias Psaradakis , Martin Sola

We consider the problem of estimating the parameters of a multivariate Bernoulli process with auto-regressive feedback in the high-dimensional setting where the number of samples available is much less than the number of parameters. This…

Statistics Theory · Mathematics 2019-03-25 Parthe Pandit , Mojtaba Sahraee-Ardakan , Arash A. Amini , Sundeep Rangan , Alyson K. Fletcher

Combining discrete probability distributions and combinatorial optimization problems with neural network components has numerous applications but poses several challenges. We propose Implicit Maximum Likelihood Estimation (I-MLE), a…

Machine Learning · Computer Science 2021-10-28 Mathias Niepert , Pasquale Minervini , Luca Franceschi

Misclassification of binary responses, if ignored, may severely bias the maximum likelihood estimators (MLE) of regression parameters. For such data, a binary regression model incorporating misclassification probabilities is extensively…

Statistics Theory · Mathematics 2020-09-28 Arindam Chatterjee , Tathagata Bandyopadhyay , Sumanta Adhya

Capturing aleatoric uncertainty is a critical part of many machine learning systems. In deep learning, a common approach to this end is to train a neural network to estimate the parameters of a heteroscedastic Gaussian distribution by…

Machine Learning · Computer Science 2022-04-04 Maximilian Seitzer , Arash Tavakoli , Dimitrije Antic , Georg Martius

Interval-censored multi-state data arise in many studies of chronic diseases, where the health status of a subject can be characterized by a finite number of disease states and the transition between any two states is only known to occur…

Methodology · Statistics 2022-09-19 Yu Gu , Donglin Zeng , Gerardo Heiss , D. Y. Lin

We consider distributed statistical optimization in one-shot setting, where there are $m$ machines each observing $n$ i.i.d. samples. Based on its observed samples, each machine then sends an $O(\log(mn))$-length message to a server, at…

Machine Learning · Computer Science 2019-11-12 Arsalan Sharifnassab , Saber Salehkaleybar , S. Jamaloddin Golestani

In finite mixtures of location-scale distributions, if there is no constraint on the parameters then the maximum likelihood estimate does not exist. But when the ratios of the scale parameters are restricted appropriately, the maximum…

Statistics Theory · Mathematics 2011-11-09 Kentaro Tanaka

The inherent bias pathology of the maximum likelihood (ML) estimation method is confirmed for models with unknown parameters $\theta$ and $\psi$ when MLE $\hat \psi$ is function of MLE $\hat \theta.$ To reduce $\hat \psi$'s bias the…

Statistics Theory · Mathematics 2014-09-11 Yannis G. Yatracos

The maximum likelihood degree (ML degree) measures the algebraic complexity of a fundamental optimization problem in statistics: maximum likelihood estimation. In this problem, one maximizes the likelihood function over a statistical model.…

Algebraic Geometry · Mathematics 2017-02-13 Jose Israel Rodriguez , Botong Wang

Suppose we are given observations, where each observation is drawn independently from one of $k$ known distributions. The goal is to match each observation to the distribution from which it was drawn. We observe that the maximum likelihood…

Data Structures and Algorithms · Computer Science 2019-10-01 Sinho Chewi , Forest Yang , Avishek Ghosh , Abhay Parekh , Kannan Ramchandran
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