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Block-coordinate descent (BCD) is a popular framework for large-scale regularized optimization problems with block-separable structure. Existing methods have several limitations. They often assume that subproblems can be solved exactly at…

Optimization and Control · Mathematics 2019-11-05 Ching-pei Lee , Stephen J. Wright

Hierarchical random effect models are used for different purposes in clinical research and other areas. In general, the main focus is on population parameters related to the expected treatment effects or group differences among all units of…

Applications · Statistics 2021-04-07 Maryna Prus , Norbert Benda , Rainer Schwabe

We propose a method for constructing optimal block designs for experiments on networks. The response model for a given network interference structure extends the linear network effects model to incorporate blocks. The optimality criteria…

Methodology · Statistics 2019-11-26 Vasiliki Koutra , Steven G. Gilmour , Ben M. Parker

Alphabetic optimality criteria, such as the $D$, $A$, and $I$ criteria, require specifying a model to select optimal designs. They are not model free and the optimal designs selected by them are not robust to model uncertainty. Recently,…

Computation · Statistics 2016-04-14 Chang-Yun Lin

We revisit the classical problem of optimal experimental design (OED) under a new mathematical model grounded in a geometric motivation. Specifically, we introduce models based on elementary symmetric polynomials; these polynomials capture…

Statistics Theory · Mathematics 2017-05-30 Zelda Mariet , Suvrit Sra

Blocking is often used to reduce known variability in designed experiments by collecting together homogeneous experimental units. A common modelling assumption for such experiments is that responses from units within a block are dependent.…

Methodology · Statistics 2018-11-07 W. G. Mueller , A. Rappold , D. C. Woods

Block coordinate descent (BCD) methods are prevalent in large scale optimization problems due to the low memory and computational costs per iteration, the predisposition to parallelization, and the ability to exploit the structure of the…

Optimization and Control · Mathematics 2025-10-31 Luis Briceño-Arias , Paulo Gonçalves , Guillaume Lauga , Nelly Pustelnik , Elisa Riccietti

Despite the success of branch-and-cut methods for solving mixed integer bilevel linear optimization problems (MIBLPs) in practice, there are still gaps in both the theory and practice surrounding these methods. In the first part of this…

Optimization and Control · Mathematics 2025-10-06 Sahar Tahernejad , Ted K. Ralphs

Block maxima methods constitute a fundamental part of the statistical toolbox in extreme value analysis. However, most of the corresponding theory is derived under the simplifying assumption that block maxima are independent observations…

Statistics Theory · Mathematics 2019-07-24 Nan Zou , Stanislav Volgushev , Axel Bücher

Decision diagrams for classification have some notable advantages over decision trees, as their internal connections can be determined at training time and their width is not bound to grow exponentially with their depth. Accordingly,…

Machine Learning · Computer Science 2022-05-31 Alexandre M. Florio , Pedro Martins , Maximilian Schiffer , Thiago Serra , Thibaut Vidal

Almost designs ($t$-adesigns) were proposed and discussed by Ding as a certain generalization of combinatorial designs related to almost difference sets. Unlike $t$-designs, it is not clear whether $t$-adesigns need also be $(t-1)$-designs…

Combinatorics · Mathematics 2018-11-19 Jerod Michel , Qi Wang

Nonregular fractional factorial designs such as Plackett-Burman designs and other orthogonal arrays are widely used in various screening experiments for their run size economy and flexibility. The traditional analysis focuses on main…

Methodology · Statistics 2008-12-17 Hongquan Xu , Frederick K. H. Phoa , Weng Kee Wong

Many existing methods for constructing optimal split-plot designs, such as D-optimal designs, only focus on minimizing the variances and covariances of the estimation for the fitted model. However, the underlying true model is usually…

Computation · Statistics 2016-08-02 Chang-Yun Lin

The concept of group divisible codes, a generalization of group divisible designs with constant block size, is introduced in this paper. This new class of codes is shown to be useful in recursive constructions for constant-weight and…

Information Theory · Computer Science 2008-07-18 Yeow Meng Chee , Gennian Ge , Alan C. H. Ling

The distributed operating room (OR) scheduling problem aims to find an assignment of surgeries to ORs across collaborating hospitals that share their waiting lists and ORs. We propose a stochastic extension of this problem where surgery…

Optimization and Control · Mathematics 2020-10-06 Cheng Guo , Merve Bodur , Dionne M. Aleman , David R. Urbach

The Maximum Balanced Biclique Problem (MBBP) is a prominent model with numerous applications. Yet, the problem is NP-hard and thus computationally challenging. We propose novel ideas for designing effective exact algorithms for MBBP.…

Discrete Mathematics · Computer Science 2017-05-23 Yi Zhou , André Rossi , Jin-Kao Hao

Intersection graphs are well-studied in the area of graph algorithms. Some intersection graph classes are known to have algorithms enumerating all unlabeled graphs by reverse search. Since these algorithms output graphs one by one and the…

Data Structures and Algorithms · Computer Science 2022-12-15 Jun Kawahara , Toshiki Saitoh , Hirokazu Takeda , Ryo Yoshinaka , Yui Yoshioka

The boundary discontinuity (BD) design is a non-experimental method for identifying causal effects that exploits a thresholding rule based on a bivariate score and a boundary curve. This widely used method generalizes the univariate…

Econometrics · Economics 2026-02-16 Matias D. Cattaneo , Rocio Titiunik , Ruiqi Rae Yu

A design is additive under an abelian group $G$ (briefly, $G$-additive) if, up to isomorphism, its point set is contained in $G$ and the elements of each block sum up to zero. The only known Steiner 2-designs that are $G$-additive for some…

Combinatorics · Mathematics 2022-09-21 Marco Buratti , Anamari Nakić

Minimizing the number of patients exposed to potentially harmful drugs in early onco logical trials is a major concern during planning. Adaptive designs account for the inherent uncertainty about the true effect size by determining the…

Applications · Statistics 2016-05-03 Kevin Kunzmann , Meinhard Kieser
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