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Within a fully microscopic setting, we derive a variational principle for the non-equilibrium steady states of chemical reaction networks, valid for time-scales over which chemical potentials can be taken to be slowly varying: at…

Molecular Networks · Quantitative Biology 2015-06-05 Andrea De Martino , Daniele De Martino , Roberto Mulet , Guido Uguzzoni

Recently gigantic peaks in thermodynamic response functions have been observed at finite temperature for one-dimensional models with short-range coupling, closely resembling a second-order phase transition. Thus, we will analyze the finite…

Statistical Mechanics · Physics 2021-02-24 Onofre Rojas

Reaction-diffusion equations are treated on infinite networks using semigroup methods. To blend high fidelity local analysis with coarse remote modeling, initial data and solutions come from a uniformly closed algebra generated by functions…

Dynamical Systems · Mathematics 2013-09-24 Robert Carlson

Fitting network models to neural activity is an important tool in neuroscience. A popular approach is to model a brain area with a probabilistic recurrent spiking network whose parameters maximize the likelihood of the recorded activity.…

Machine Learning · Statistics 2021-11-16 Guillaume Bellec , Shuqi Wang , Alireza Modirshanechi , Johanni Brea , Wulfram Gerstner

The interactions between the components of many real-world systems are best modelled by networks with multiple layers. Different theories have been proposed to explain how multilayered connections affect the linear stability of…

Physics and Society · Physics 2022-03-25 Charo I. del Genio , Sergio Faci-Lázaro , Jesús Gómez-Gardeñes , Stefano Boccaletti

Empirically derived continuum models of collective behavior among large populations of dynamic agents are a subject of intense study in several fields, including biology, engineering and finance. We formulate and study a mean-field game…

Adaptation and Self-Organizing Systems · Physics 2018-06-22 Piyush Grover , Kaivalya Bakshi , Evangelos A. Theodorou

We consider spatially extended systems of interacting nonlinear Hawkes processes modeling large systems of neurons placed in Rd and study the associated mean field limits. As the total number of neurons tends to infinity, we prove that the…

Probability · Mathematics 2018-02-19 Julien Chevallier , A Duarte , E Löcherbach , G Ost

We consider an interacting system of one-dimensional structures modelling fibers with fiber-fiber interaction in a fiber lay-down process. The resulting microscopic system is investigated by looking at different asymptotic limits of the…

Dynamical Systems · Mathematics 2017-10-06 Raul Borsche , Axel Klar , Christian Nessler , Andreas Roth , Oliver Tse

Voltage-sensitive dye imaging (VSDi) has revealed fundamental properties of neocortical processing at mesoscopic scales. Since VSDi signals report the average membrane potential, it seems natural to use a mean-field formalism to model such…

Neurons and Cognition · Quantitative Biology 2017-03-03 Yann Zerlaut , Alain Destexhe

We derive the mean-field equations arising as the limit of a network of interacting spiking neurons, as the number of neurons goes to infinity. The neurons belong to a fixed number of populations and are represented either by the…

Neurons and Cognition · Quantitative Biology 2016-11-25 Javier Baladron , Diego Fasoli , Olivier Faugeras , Jonathan Touboul

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

Probability · Mathematics 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

How biological networks achieve robust control despite relying on imperfect, local information remains an important open question. Here, we identify thermodynamic constraints that can curtail non-equilibrium steady-state responses so…

Statistical Mechanics · Physics 2026-05-27 Carlos Floyd , Aaron R. Dinner , Suriyanarayanan Vaikuntanathan

The observation of critical-like behavior in cortical networks represents a major step forward in elucidating how the brain manages information. Understanding the origin and functionality of critical-like dynamics, as well as their…

Neurons and Cognition · Quantitative Biology 2015-06-22 Paula Villa Martín , Paolo Moretti , Miguel A. Muñoz

Several data-driven approaches based on information theory have been proposed for analyzing high-order interactions involving three or more components of a network system. Most of these methods are defined only in the time domain and rely…

Applications · Statistics 2025-03-18 Yuri Antonacci , Chiara Bara' , Laura Sparacino , Gorana Mijatovic , Ludovico Minati , Luca Faes

We study an abstracted model of neuronal activity via numerical simulation, and report spatiotemporal pattern formation and critical like dynamics. A population of pulse coupled, discretised, relaxation oscillators is simulated over…

Neurons and Cognition · Quantitative Biology 2019-04-24 Dionysios Georgiadis , Didier Sornette

We consider particle-based stochastic reaction-drift-diffusion models where particles move via diffusion and drift induced by one- and two-body potential interactions. The dynamics of the particles are formulated as measure-valued…

Probability · Mathematics 2025-01-22 Max Heldman , Samuel A. Isaacson , Qianhan Liu , Konstantinos Spiliopoulos

We investigate the mean-field limit for interacting particle systems through a duality-based framework and obtain quantitative estimates on the convergence of marginals as well as on correlation functions. In particular, for merely…

Analysis of PDEs · Mathematics 2026-05-05 Nadia Khoury , P. -E. Jabin

For infinitely large sparse networks of spiking neurons mean field theory shows that a balanced state of highly irregular activity arises under various conditions. Here we analytically investigate the microscopic irregular dynamics in…

Disordered Systems and Neural Networks · Physics 2009-11-13 Sven Jahnke , Raoul-Martin Memmesheimer , Marc Timme

In a multiplex network, a set of nodes is connected by different types of interactions, each represented as a separate layer within the network. Multiplexes have emerged as a key instrument for modeling large-scale complex systems, due to…

Probability · Mathematics 2025-10-13 Ankan Ganguly , Bhaswar B. Bhattacharya

Mesoscopic models of finite-size neuronal populations are crucial to understand the dynamics of neural networks in the brain, especially their fluctuations and response to stimuli. However, current theories to derive such models are based…

Neurons and Cognition · Quantitative Biology 2026-01-26 Nils E. Greven , Jonas Ranft , Tilo Schwalger
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