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State-space models (SSMs) offer a powerful framework for dynamical system analysis, wherein the temporal dynamics of the system are assumed to be captured through the evolution of the latent states, which govern the values of the…

Machine Learning · Statistics 2024-12-17 Jiahe Lin , George Michailidis

The development of enhanced sampling methods has greatly extended the scope of atomistic simulations, allowing long-time phenomena to be studied with accessible computational resources. Many such methods rely on the identification of an…

Computational Physics · Physics 2022-06-08 Luigi Bonati , GiovanniMaria Piccini , Michele Parrinello

In this paper, we present new optimization models for Support Vector Machine (SVM), with the aim of separating data points in two or more classes. The classification task is handled by means of nonlinear classifiers induced by kernel…

Optimization and Control · Mathematics 2025-07-15 Francesca Maggioni , Andrea Spinelli

A variety of enhanced sampling methods predict multidimensional free energy landscapes associated with biological and other molecular processes as a function of a few selected collective variables (CVs). The accuracy of these methods is…

Computational Physics · Physics 2024-04-09 Lukas Müllender , Andrea Rizzi , Michele Parrinello , Paolo Carloni , Davide Mandelli

The increasing congestion of the radio frequency spectrum presents challenges for efficient spectrum utilization. Cognitive radio systems enable dynamic spectrum access with the aid of recent innovations in neural networks. However,…

Machine Learning · Computer Science 2025-08-25 Sangwon Shin , Mehmet C. Vuran

Several enhanced sampling techniques rely on the definition of collective variables to effectively explore free energy landscapes. Existing variables that describe the progression along a reactive pathway offer an elegant solution but face…

Chemical Physics · Physics 2024-02-05 Thorben Fröhlking , Luigi Bonati , Valerio Rizzi , Francesco Luigi Gervasio

Speed-of-sound has been shown as a potential biomarker for breast cancer imaging, successfully differentiating malignant tumors from benign ones. Speed-of-sound images can be reconstructed from time-of-flight measurements from ultrasound…

Image and Video Processing · Electrical Eng. & Systems 2020-07-23 Melanie Bernhardt , Valery Vishnevskiy , Richard Rau , Orcun Goksel

Current Deep Learning methods for environment segmentation and velocity estimation rely on Convolutional Recurrent Neural Networks to exploit spatio-temporal relationships within obtained sensor data. These approaches derive scene dynamics…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Marco Braun , Moritz Luszek , Mirko Meuter , Dominic Spata , Kevin Kollek , Anton Kummert

Very deep convolutional neural networks (CNNs) have been firmly established as the primary methods for many computer vision tasks. However, most state-of-the-art CNNs are large, which results in high inference latency. Recently, depth-wise…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Yihui He , Jianing Qian , Jianren Wang , Cindy X. Le , Congrui Hetang , Qi Lyu , Wenping Wang , Tianwei Yue

Portable, low-field Magnetic Resonance Imaging (MRI) scanners are increasingly being deployed in clinical settings. However, key barriers to their widespread use include low signal-to-noise ratio (SNR), generally low image quality, and long…

Non-volatile memory (NVM) technologies such as spin-transfer torque magnetic random access memory (STT-MRAM) and spin-orbit torque magnetic random access memory (SOT-MRAM) have significant advantages compared to conventional SRAM due to…

Hardware Architecture · Computer Science 2022-05-23 Ahmet Inci , Mehmet Meric Isgenc , Diana Marculescu

The heat shock protein 90 (Hsp90) is a molecular chaperone that controls the folding and activation of client proteins using the free energy of ATP hydrolysis. The Hsp90 active site is in its N-terminal domain (NTD). Our goal is to…

Computational Physics · Physics 2023-07-26 Zineb Belkacemi , Marc Bianciotto , Herve Minoux , Tony Lelievre , Gabriel Stoltz , Paraskevi Gkeka

The growing prevalence of inverter-based resources (IBRs) for renewable energy integration and electrification greatly challenges power system dynamic analysis. To account for both synchronous generators (SGs) and IBRs, this work presents…

Systems and Control · Electrical Eng. & Systems 2024-09-24 Shaohui Liu , Weiqian Cai , Hao Zhu , Brian Johnson

In this paper, we present a deep learning-based reduced-order model (DL-ROM) for the stability prediction of unsteady 3D fluid-structure interaction systems. The proposed DL-ROM has the format of a nonlinear state-space model and employs a…

Fluid Dynamics · Physics 2021-12-21 A. Chizfahm , R. Jaiman

Recent progress in diffusion-based visual generation has largely relied on latent diffusion models with variational autoencoders (VAEs). While effective for high-fidelity synthesis, this VAE+diffusion paradigm suffers from limited training…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Minglei Shi , Haolin Wang , Wenzhao Zheng , Ziyang Yuan , Xiaoshi Wu , Xintao Wang , Pengfei Wan , Jie Zhou , Jiwen Lu

Extending spatio-temporal scale limitations of models for complex atomistic systems considered in biochemistry and materials science necessitates the development of enhanced sampling methods. The potential acceleration in exploring the…

Machine Learning · Statistics 2019-01-18 Markus Schöberl , Nicholas Zabaras , Phaedon-Stelios Koutsourelakis

Latent variable models (LVMs) with discrete compositional latents are an important but challenging setting due to a combinatorially large number of possible configurations of the latents. A key tradeoff in modeling the posteriors over…

Machine Learning · Computer Science 2023-06-06 Edward J. Hu , Nikolay Malkin , Moksh Jain , Katie Everett , Alexandros Graikos , Yoshua Bengio

Symbolic regression (SR) is a powerful technique for discovering the underlying mathematical expressions from observed data. Inspired by the success of deep learning, recent deep generative SR methods have shown promising results. However,…

Machine Learning · Computer Science 2024-06-04 Wenqiang Li , Weijun Li , Lina Yu , Min Wu , Linjun Sun , Jingyi Liu , Yanjie Li , Shu Wei , Yusong Deng , Meilan Hao

We present SrvfNet, a generative deep learning framework for the joint multiple alignment of large collections of functional data comprising square-root velocity functions (SRVF) to their templates. Our proposed framework is fully…

Computer Vision and Pattern Recognition · Computer Science 2021-04-29 Elvis Nunez , Andrew Lizarraga , Shantanu H. Joshi

Time-lagged autoencoders (TAEs) have been proposed as a deep learning regression-based approach to the discovery of slow modes in dynamical systems. However, a rigorous analysis of nonlinear TAEs remains lacking. In this work, we discuss…

Machine Learning · Statistics 2019-09-04 Wei Chen , Hythem Sidky , Andrew L. Ferguson