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Designing RNA molecules has garnered recent interest in medicine, synthetic biology, biotechnology and bioinformatics since many functional RNA molecules were shown to be involved in regulatory processes for transcription, epigenetics and…

Machine Learning · Computer Science 2019-04-15 Frederic Runge , Danny Stoll , Stefan Falkner , Frank Hutter

Deep neural networks and decision trees operate on largely separate paradigms; typically, the former performs representation learning with pre-specified architectures, while the latter is characterised by learning hierarchies over…

Neural and Evolutionary Computing · Computer Science 2019-06-11 Ryutaro Tanno , Kai Arulkumaran , Daniel C. Alexander , Antonio Criminisi , Aditya Nori

Machine learning is advancing towards a data-science approach, implying a necessity to a line of investigation to divulge the knowledge learnt by deep neuronal networks. Limiting the comparison among networks merely to a predefined…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Arash Akbarinia , Karl R. Gegenfurtner

Topological data analysis (TDA) approaches are becoming increasingly popular for studying the dependence patterns in multivariate time series data. In particular, various dependence patterns in brain networks may be linked to specific tasks…

Methodology · Statistics 2025-12-08 Anass El Yaagoubi Bourakna , Moo K. Chung , Hernando Ombao

RNA function crucially depends on its structure. Thermodynamic models currently used for secondary structure prediction rely on computing the partition function of folding ensembles, and can thus estimate minimum free-energy structures and…

Biomolecules · Quantitative Biology 2022-07-26 Nicola Calonaci , Alisha Jones , Francesca Cuturello , Michael Sattler , Giovanni Bussi

Learning to compute, the ability to model the functional behavior of a circuit graph, is a fundamental challenge for graph representation learning. Yet, the dominant paradigm is architecturally mismatched for this task. This flawed…

Artificial Intelligence · Computer Science 2026-02-10 Ziyang Zheng , Jiaying Zhu , Jingyi Zhou , Qiang Xu

Despite their success and widespread adoption, the opaque nature of deep neural networks (DNNs) continues to hinder trust, especially in critical applications. Current interpretability solutions often yield inconsistent or oversimplified…

Machine Learning · Computer Science 2024-10-10 Alec F. Diallo , Vaishak Belle , Paul Patras

Given the ubiquitous existence of graph-structured data, learning the representations of nodes for the downstream tasks ranging from node classification, link prediction to graph classification is of crucial importance. Regarding missing…

Machine Learning · Computer Science 2022-04-21 Bisheng Li , Min Zhou , Shengzhong Zhang , Menglin Yang , Defu Lian , Zengfeng Huang

What types of numeric representations emerge in neural systems, and what would a satisfying answer to this question look like? In this work, we interpret Neural Network (NN) solutions to sequence based number tasks using a variety of…

Machine Learning · Computer Science 2025-08-19 Satchel Grant , Noah D. Goodman , James L. McClelland

The automation of scientific research workflows has emerged as a transformative frontier in artificial intelligence, yet existing autonomous research agents remain largely domain-agnostic, lacking the specialized reasoning, method…

Artificial Intelligence · Computer Science 2026-05-05 Bing Zhou , Xiao Huang , Huan Ning , Qiusheng Wu , Diya Li , Ziyi Zhang

Deep learning methods have demonstrated outstanding performances on classification and regression tasks on homogeneous data types (e.g., image, audio, and text data). However, tabular data still pose a challenge, with classic machine…

Machine Learning · Computer Science 2023-11-15 Antonio Briola , Yuanrong Wang , Silvia Bartolucci , Tomaso Aste

The design of handcrafted neural networks requires a lot of time and resources. Recent techniques in Neural Architecture Search (NAS) have proven to be competitive or better than traditional handcrafted design, although they require domain…

Machine Learning · Computer Science 2021-03-17 Cat P. Le , Mohammadreza Soltani , Robert Ravier , Vahid Tarokh

Improvements in experimental and computational technologies have led to significant increases in data available for analysis. Topological data analysis (TDA) is an emerging area of mathematical research that can identify structures in these…

Quantitative Methods · Quantitative Biology 2022-07-25 Maria-Veronica Ciocanel , Riley Juenemann , Adriana T. Dawes , Scott A. McKinley

Graph neural networks (GNNs) are increasingly used to model biological systems, yet the reliability of post-hoc explanation methods for recovering meaningful molecular mechanisms remains unclear. Here, we systematically evaluate four widely…

Molecular Networks · Quantitative Biology 2026-05-22 Kyle Higgins , Ivan Laponogov , Dennis Veselkov , Kirill Veselkov

Network science provides valuable insights across numerous disciplines including sociology, biology, neuroscience and engineering. A task of major practical importance in these application domains is inferring the network structure from…

Machine Learning · Computer Science 2019-05-01 Vassilis N. Ioannidis , Yanning Shen , Georgios B. Giannakis

We consider the analysis of high dimensional data given in the form of a matrix with columns consisting of observations and rows consisting of features. Often the data is such that the observations do not reside on a regular grid, and the…

Machine Learning · Statistics 2017-08-22 Gal Mishne , Ronen Talmon , Israel Cohen , Ronald R. Coifman , Yuval Kluger

In a decentralized machine learning system, data is typically partitioned among multiple devices or nodes, each of which trains a local model using its own data. These local models are then shared and combined to create a global model that…

Machine Learning · Computer Science 2023-08-01 Luigi Palmieri , Lorenzo Valerio , Chiara Boldrini , Andrea Passarella

We apply bio-inspired methods for the analysis of different dynamic bibliometric networks (linking papers by citation, authors, and keywords, respectively). Biological species are clusters of individuals defined by widely different criteria…

Digital Libraries · Computer Science 2011-01-20 Sandor Soos , George Kampis

Long-Tailed (LT) recognition has been widely studied to tackle the challenge of imbalanced data distributions in real-world applications. However, the design of neural architectures for LT settings has received limited attention, despite…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Yuhan Pan , Yanan Sun , Wei Gong

This thesis presents a new methodology to analyze one-dimensional signals trough a new approach called Multi Layer Analysis, for short MLA. It also provides some new insights on the relationship between one-dimensional signals processed by…

Computer Vision and Pattern Recognition · Computer Science 2011-07-28 Luca Pinello
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