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We introduce a novel direct calibration algorithm to address phase delay, gain, and offset mismatches in Analog-to-Digital Converter (ADC) time interleaving systems. These mismatches, common in high-speed data acquisition, degrade system…

Instrumentation and Methods for Astrophysics · Physics 2025-11-27 Chi-kwan Chan , Hina Suzuki , David Forbes , Andrew Thomas West , Arash Roshanineshat , Daniel P. Marrone , Amy Lowitz

Gravitational-wave detection strategies are based on a signal analysis technique known as matched filtering. Despite the success of matched filtering, due to its computational cost, there has been recent interest in developing deep…

General Relativity and Quantum Cosmology · Physics 2022-11-03 Dwyer S. Deighan , Scott E. Field , Collin D. Capano , Gaurav Khanna

This paper presents a novel attention-based algorithm for achieving adaptive computation called DACT, which, unlike existing ones, is end-to-end differentiable. Our method can be used in conjunction with many networks; in particular, we…

Artificial Intelligence · Computer Science 2020-05-25 Cristobal Eyzaguirre , Alvaro Soto

Non-negative matrix factorization (NMF) has become a popular machine learning approach to many problems in text mining, speech and image processing, bio-informatics and seismic data analysis to name a few. In NMF, a matrix of non-negative…

Numerical Analysis · Computer Science 2013-03-19 Hugo Van hamme

Physics-Informed Neural Networks (PINNs) have emerged as a tool for approximating the solution of Partial Differential Equations (PDEs) in both forward and inverse problems. PINNs minimize a loss function which includes the PDE residual…

Numerical Analysis · Mathematics 2025-09-23 Coen Visser , Alexander Heinlein , Bianca Giovanardi

Despite success on a wide range of problems related to vision, generative adversarial networks (GANs) often suffer from inferior performance due to unstable training, especially for text generation. To solve this issue, we propose a new…

Machine Learning · Computer Science 2020-11-02 Yue Wu , Pan Zhou , Andrew Gordon Wilson , Eric P. Xing , Zhiting Hu

Aligning millions of short DNA or RNA reads, of 75 to 250 base pairs each, to a reference genome is a significant computation problem in bioinformatics. We present a flexible and fast FPGA-based short read alignment tool. Our aligner makes…

Genomics · Quantitative Biology 2018-05-02 Nathaniel McVicar , Akina Hoshino , Anna La Torre , Thomas A. Reh , Walter L. Ruzzo , Scott Hauck

Recent technological advances in Next Generation Sequencing tools have led to increasing speeds of DNA sample collection, preparation, and sequencing. One instrument can produce over 600 Gb of genetic sequence data in a single run. This…

Quantitative Methods · Quantitative Biology 2016-11-18 Stephanie Dodson , Darrell O. Ricke , Jeremy Kepner

Generative adversarial networks (GANs) usually struggle in learning from highly diverse data, whose underlying manifold is complex. In this work, we revisit the mathematical foundations of GANs, and theoretically reveal that the native…

Machine Learning · Computer Science 2025-10-02 Mengfei Xia , Yujun Shen , Ceyuan Yang , Ran Yi , Wenping Wang , Yong-Jin Liu

The tremdendous advances in high-throughput sequencing technologies have made population-scale sequencing as performed in the 1000 Genomes project and the Genome of the Netherlands project possible. Next-generation sequencing has allowed…

Genomics · Quantitative Biology 2013-03-15 Tobias Marschall , Alexander Schönhuth

Raven's Progressive Matrices are a benchmark originally designed to test the cognitive abilities of humans. It has recently been adapted to test relational reasoning in machine learning systems. For this purpose the so-called Procedurally…

Machine Learning · Computer Science 2020-03-27 Marius Jahrens , Thomas Martinetz

The exponential growth of DNA sequencing data has outpaced traditional heuristic-based methods, which struggle to scale effectively. Efficient computational approaches are urgently needed to support large-scale similarity search, a…

Our work tackles the computational challenges of contrastive learning methods, particularly for the pretraining of Vision Transformers (ViTs). Despite the effectiveness of contrastive learning, the substantial computational resources…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jinhong Lin , Cheng-En Wu , Yibing Wei , Pedro Morgado

Test-time adaptation (TTA) is an effective approach to mitigate performance degradation of trained models when encountering input distribution shifts at test time. However, existing TTA methods often suffer significant performance drops…

Machine Learning · Computer Science 2025-02-06 Minguk Jang , Hye Won Chung

Identifying similar protein sequences is a core step in many computational biology pipelines such as detection of homologous protein sequences, generation of similarity protein graphs for downstream analysis, functional annotation and gene…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-01 Oguz Selvitopi , Saliya Ekanayake , Giulia Guidi , Georgios Pavlopoulos , Ariful Azad , Aydin Buluc

Genetic Algorithms (GAs) are used to solve search and optimization problems in which an optimal solution can be found using an iterative process with probabilistic and non-deterministic transitions. However, depending on the problem's…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-23 Matheus F. Torquato , Marcelo A. C. Fernandes

Combined inference for heterogeneous high-dimensional data is critical in modern biology, where clinical and various kinds of molecular data may be available from a single study. Classical genetic association studies regress a single…

Applications · Statistics 2017-03-22 Hélène Ruffieux , Anthony C. Davison , Jörg Hager , Irina Irincheeva

Raven's Progressive Matrices are multiple-choice intelligence tests, where one tries to complete the missing location in a $3\times 3$ grid of abstract images. Previous attempts to address this test have focused solely on selecting the…

Artificial Intelligence · Computer Science 2020-11-03 Niv Pekar , Yaniv Benny , Lior Wolf

Supervised deep learning methods are enjoying enormous success in many practical applications of computer vision and have the potential to revolutionize robotics. However, the marked performance degradation to biases and imbalanced data…

Computer Vision and Pattern Recognition · Computer Science 2020-08-14 Aadarsh Sahoo , Ankit Singh , Rameswar Panda , Rogerio Feris , Abir Das

We introduce Deep Adaptive Design (DAD), a method for amortizing the cost of adaptive Bayesian experimental design that allows experiments to be run in real-time. Traditional sequential Bayesian optimal experimental design approaches…

Machine Learning · Statistics 2021-06-14 Adam Foster , Desi R. Ivanova , Ilyas Malik , Tom Rainforth