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Meta-analysis is a statistical method used in evidence synthesis for combining, analyzing and summarizing studies that have the same target endpoint and aims to derive a pooled quantitative estimate using fixed and random effects models or…

Methodology · Statistics 2022-04-25 Ivette Raices Cruz , Matthias C. M. Troffaes , Johan Lindström , Ullrika Sahlin

Antibiotic resistance is a major threat to global health. It emerges in multispecies microbial communities under antibiotic exposure. This makes antibiotic spectrum -- a drug's distribution of effects across species -- a potential key…

Populations and Evolution · Quantitative Biology 2026-04-21 Magnus Aspenberg , Erik Andreas Martens , Kristofer Wollein Waldetoft

Here we present the first genome wide statistical test for recessive selection. This test uses explicitly non-equilibrium demographic differences between populations to infer the mode of selection. By analyzing the transient response to a…

Populations and Evolution · Quantitative Biology 2014-03-24 Daniel J. Balick , Ron Do , David Reich , Shamil R. Sunyaev

In a regression analysis, suppose we suspect that there are several heterogeneous groups in the population that a sample represents. Mixture regression models have been applied to address such problems. By modeling the conditional…

Methodology · Statistics 2013-07-02 Toshiya Hoshikawa

Covariate balance is a conventional key diagnostic for methods used estimating causal effects from observational studies. Recently, there is an emerging interest in directly incorporating covariate balance in the estimation. We study a…

Methodology · Statistics 2017-02-14 Qingyuan Zhao , Daniel Percival

Difficulties identifying appropriate biodiversity impact metrics remain a major barrier to inclusion of biodiversity considerations in environmentally responsible investment. We propose and analyse a simple science-based local metric: the…

Populations and Evolution · Quantitative Biology 2023-03-21 Axel G. Rossberg , Jacob D. O'Sullivan , Svetlana Malysheva , Nadav M. Shnerb

In this paper, we propose a fractional differential equation of order one-half, to model the evolution through time of the dynamics of accumulation and elimination of the contaminant in human organism with a deficient immune system, during…

Methodology · Statistics 2022-07-28 Komla Elom Adedje , Diakarya Barro

Human microbiome studies based on genetic sequencing techniques produce compositional longitudinal data of the relative abundances of microbial taxa over time, allowing to understand, through mixed-effects modeling, how microbial…

Methodology · Statistics 2025-12-23 John Barrera , Cristian Meza , Ana Arribas-Gil

We derive a linear recursion relation for the species abundance distribution in a statistical model of ecology and demonstrate the existence of a scaling solution.

Statistical Mechanics · Physics 2013-05-29 Hector Garcia Martin , Nigel Goldenfeld

The statistical problem of using an initial sample to estimate the number of species in a larger sample has found important applications in fields far removed from ecology. Here we address the general problem of estimating the number of…

Methodology · Statistics 2018-05-16 Chao Deng , Timothy Daley , Peter Calabrese , Jie Ren , Andrew D. Smith

Count data appears in various disciplines. In this work, a new method to analyze time series count data has been proposed. The method assumes exponentially decaying covariance structure, a special class of the Mat\'ern covariance function,…

Methodology · Statistics 2021-02-19 Soudeep Deb

It is widely accepted that population genetics theory is the cornerstone of evolutionary analyses. Empirical tests of the theory, however, are challenging because of the complex relationships between space, dispersal, and evolution.…

Populations and Evolution · Quantitative Biology 2011-10-26 Kirill S. Korolev , Joao B. Xavier , David R. Nelson , Kevin R. Foster

This paper develops a Bayesian graphical model for fusing disparate types of count data. The motivating application is the study of bacterial communities from diverse high dimensional features, in this case transcripts, collected from…

Prevalent cohort sampling is commonly used to study the natural history of a disease when the disease is rare or it usually takes a long time to observe the failure event. It is known, however, that the collected sample in this situation is…

Methodology · Statistics 2022-09-05 Omidali Aghababaei Jazi

Branching process inspired models are widely used to estimate the effective reproduction number -- a useful summary statistic describing an infectious disease outbreak -- using counts of new cases. Case data is a real-time indicator of…

Methodology · Statistics 2023-10-03 Isaac H. Goldstein , Jon Wakefield , Volodymyr M. Minin

Method of parameterizing and smoothing the unknown underling distributions using Bernstein polynomials is proposed, verified and investigated. Any distribution with bounded and smooth enough density can be approximated by the proposed…

Methodology · Statistics 2015-06-23 Zhong Guan

Envelope model also known as multivariate regression model was proposed to solve the multiple response regression problems. It measures the linear association between predictors and multiple responses by using the minimal reducing subspace…

Methodology · Statistics 2018-05-07 Bochao Jia

In most circumstances, probability sampling is the only way to ensure unbiased inference about population quantities where a complete census is not possible. As we enter the era of 'big data', however, nonprobability samples, whose sampling…

Applications · Statistics 2023-01-18 Robin J. Boyd , Gary D. Powney , Oliver L. Pescott

Event counts are response variables with non-negative integer values representing the number of times that an event occurs within a fixed domain such as a time interval, a geographical area or a cell of a contingency table. Analysis of…

We consider a binary unsupervised classification problem where each observation is associated with an unobserved label that we want to retrieve. More precisely, we assume that there are two groups of observation: normal and abnormal. The…

Machine Learning · Statistics 2011-05-05 Stevenn Volant , Marie-Laure Martin Magniette , Stéphane Robin