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We propose a principled framework for nonparametric empirical Bayes (EB) estimation, based on the idea that the prior should be consistent with the observed posterior and that Bayesian updating should be stable. Focusing on discretized…

Methodology · Statistics 2025-07-14 Valentino Dardanoni , Stefano Demichelis

We review some aspects of Bayesian and frequentist interval estimation, focusing first on their relative strengths and weaknesses when used in "clean" or "textbook" contexts. We then turn attention to observational-data situations which are…

Methodology · Statistics 2010-10-05 Paul Gustafson , Sander Greenland

Evaluating treatment effect heterogeneity widely informs treatment decision making. At the moment, much emphasis is placed on the estimation of the conditional average treatment effect via flexible machine learning algorithms. While these…

Methodology · Statistics 2021-05-07 Lihua Lei , Emmanuel J. Candès

To quantify uncertainty around point estimates of conditional objects such as conditional means or variances, parameter uncertainty has to be taken into account. Attempts to incorporate parameter uncertainty are typically based on the…

Econometrics · Economics 2019-01-23 Eric Beutner , Alexander Heinemann , Stephan Smeekes

Observational healthcare data offer the potential to estimate causal effects of medical products on a large scale. However, the confidence intervals and p-values produced by observational studies only account for random error and fail to…

Applications · Statistics 2024-05-02 Jami J. Mulgrave , David Madigan , George Hripcsak

What, if anything, should a frequentist say about a single realized confidence interval (CI) and its chance of having covered the parameter? Jerzy Neyman's original answer was to refuse any nondegenerate probability for coverage ex post…

Other Statistics · Statistics 2026-03-06 Scott Lee

Bayes factors for composite hypotheses have difficulty in encoding vague prior knowledge, as improper priors cannot be used and objective priors may be subjectively unreasonable. To address these issues I revisit the posterior Bayes factor,…

Methodology · Statistics 2024-02-29 Frank Dudbridge

Interim analyses are vital in clinical trials for early decision-making. While frequentist implications are well-established, the consequences of repeated Bayesian interim monitoring for efficacy, specifically regarding multiplicity, remain…

Methodology · Statistics 2025-12-30 Suyu Liu , Beibei Guo , Laura Thompson , Lei Nie , Ying Yuan

We study methods for simultaneous analysis of many noisy and biased estimates, each paired with an even noisier estimate of its own bias. The analyst's goal is to construct short calibrated intervals for each parameter. The standard…

Methodology · Statistics 2026-05-11 Wanyi Ling , Sida Li , Junming Guan , Nikolaos Ignatiadis

We consider the asymptotic behavior of posterior distributions and Bayes estimators based on observations which are required to be neither independent nor identically distributed. We give general results on the rate of convergence of the…

Statistics Theory · Mathematics 2009-09-29 Subhashis Ghosal , Aad van der Vaart

We investigate the frequentist coverage of Bayesian credible sets in a nonparametric setting. We consider a scale of priors of varying regularity and choose the regularity by an empirical Bayes method. Next we consider a central set of…

Statistics Theory · Mathematics 2016-08-11 Botond Szabó , A. W. van der Vaart , J. H. van Zanten

Don Fraser has given an interesting account of the agreements and disagreements between Bayesian posterior probabilities and confidence levels. In this comment I discuss some cases where the lack of such agreement is extreme. I then discuss…

Methodology · Statistics 2012-02-06 Larry Wasserman

This paper revisits the simple, but empirically salient, problem of inference on a real-valued parameter that is partially identified through upper and lower bounds with asymptotically normal estimators. A simple confidence interval is…

Econometrics · Economics 2021-01-01 Jörg Stoye

Standard confidence intervals employed in applied statistical analysis are usually based on asymptotic approximations. Such approximations can be considerably inaccurate in small and moderate sized samples. We derive accurate confidence…

Statistics Theory · Mathematics 2020-12-14 Eliane C. Pinheiro , Silvia L. P. Ferrari , Francisco M. C. Medeiros

We investigate the credible sets and marginal credible intervals resulting from the horseshoe prior in the sparse multivariate normal means model. We do so in an adaptive setting without assuming knowledge of the sparsity level (number of…

Statistics Theory · Mathematics 2017-02-14 Stéphanie van der Pas , Botond Szabó , Aad van der Vaart

We develop a set of scalable Bayesian inference procedures for a general class of nonparametric regression models. Specifically, nonparametric Bayesian inferences are separately performed on each subset randomly split from a massive…

Statistics Theory · Mathematics 2019-09-05 Zuofeng Shang , Botao Hao , Guang Cheng

A prediction interval covers a future observation from a random process in repeated sampling, and is typically constructed by identifying a pivotal quantity that is also an ancillary statistic. Analogously, a tolerance interval covers a…

Methodology · Statistics 2022-01-19 Geoffrey S Johnson

We propose and study three confidence intervals (CIs) centered at an estimator that is intentionally biased to reduce mean squared error. The first CI simply uses an unbiased estimator's standard error; compared to centering at the unbiased…

Econometrics · Economics 2025-02-04 David M. Kaplan , Xin Liu

This paper concerns the construction of confidence intervals in standard seroprevalence surveys. In particular, we discuss methods for constructing confidence intervals for the proportion of individuals in a population infected with a…

Applications · Statistics 2021-10-05 Thomas J. DiCiccio , David M. Ritzwoller , Joseph P. Romano , Azeem M. Shaikh

We consider the problem of interval estimation of the odds ratio. An asymptotic confidence interval is widely applied in medical research. Unfortunately that confidence interval has a poor coverage probability: it is significantly smaller…

Methodology · Statistics 2020-11-19 Zofia Zielińska-Kolasińska , Wojciech Zieliński