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The group testing problem consists of determining a small set of defective items from a larger set of items based on a number of possibly-noisy tests, and has numerous practical applications. One of the defining features of group testing is…

Information Theory · Computer Science 2021-11-12 Bernard Teo , Jonathan Scarlett

In the current pandemic, testing continues to be the most important tool for monitoring and curbing the disease spread and early identification of the disease to perform health-related interventions like quarantine, contact tracing and etc.…

Cryptography and Security · Computer Science 2020-12-08 Abhishek Singh , Ramesh Raskar

The practice of pooling several individual test statistics to form aggregate tests is common in many statistical application where individual tests may be underpowered. While selection by aggregate tests can serve to increase power, the…

Methodology · Statistics 2020-12-08 Ruth Heller , Amit Meir , Nilanjan Chatterjee

As humanity struggles to contain the global Covid-19 infection, prophylactic actions are grandly slowed down by the shortage of testing kits. Governments have taken several measures to work around this shortage: the FDA has become more…

The goal of group testing is to efficiently identify a few specific items, called positives, in a large population of items via tests. A test is an action on a subset of items which returns positive if the subset contains at least one…

Information Theory · Computer Science 2021-11-08 Thach V. Bui , Mahdi Cheraghchi , An T. H. Nguyen , Thuc D. Nguyen

We study the problem usually referred to as group testing in the context of COVID-19. Given n samples collected from patients, how should we select and test mixtures of samples to maximize information and minimize the number of tests? Group…

Machine Learning · Computer Science 2020-08-07 Louis Abraham , Gary Becigneul , Benjamin Coleman , Bernhard Scholkopf , Anshumali Shrivastava , Alexander Smola

Identifying the infection status of each individual during infectious diseases informs public health management. However, performing frequent individual-level tests may not be feasible. Instead, sparse and sometimes group-level tests are…

Applications · Statistics 2023-06-06 Zahra Gholamalian , Zeinab Maleki , MasoudReza Hashemi , Pouria Ramazi

Surveillance of diseases in a pandemic is an important part of public health policy. Diagnostic testing at the individual level is often infeasible due to resource constraints. To circumvent these constraints, group testing can be applied.…

Computation · Statistics 2026-04-01 Michael Balzer , Kainat Khowaja , Christiane Fuchs

We consider the problem of detecting a small subset of defective items from a large set via non-adaptive "random pooling" group tests. We consider both the case when the measurements are noiseless, and the case when the measurements are…

Information Theory · Computer Science 2011-07-25 Chun Lam Chan , Pak Hou Che , Sidharth Jaggi , Venkatesh Saligrama

The original problem of group testing consists in the identification of defective items in a collection, by applying tests on groups of items that detect the presence of at least one defective item in the group. The aim is then to identify…

Applications · Statistics 2021-06-10 Emilien Joly , Bastien Mallein

Clustering is part of unsupervised analysis methods that consist in grouping samples into homogeneous and separate subgroups of observations also called clusters. To interpret the clusters, statistical hypothesis testing is often used to…

Methodology · Statistics 2022-10-25 Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris P Hejblum

We propose a novel testing and containment strategy in order to contain the spread of SARS-CoV2 while permitting large parts of the population to resume social and economic activity. Our approach recognises the fact that testing capacities…

Populations and Evolution · Quantitative Biology 2020-04-29 Jakob Jonnerby , Philip Lazos , Edwin Lock , Francisco Marmolejo-Cossío , C. Bronk Ramsey , Meghana Shukla , Divya Sridhar

An important aspect of multiple hypothesis testing is controlling the significance level, or the level of Type I error. When the test statistics are not independent it can be particularly challenging to deal with this problem, without…

Statistics Theory · Mathematics 2009-03-04 Sandy Clarke , Peter Hall

Parametric inference posits a statistical model that is a specified family of probability distributions. Restricted inference, e.g., restricted likelihood ratio testing, attempts to exploit the structure of a statistical submodel that is a…

Statistics Theory · Mathematics 2019-03-22 Michael W. Trosset , Carey E. Priebe

When testing for a disease such as COVID-19, the standard method is individual testing: we take a sample from each individual and test these samples separately. An alternative is pooled testing (or "group testing"), where samples are mixed…

Applications · Statistics 2021-12-14 Matthew Aldridge , David Ellis

A key requirement in containing contagious diseases, such as the Coronavirus disease 2019 (COVID-19) pandemic, is the ability to efficiently carry out mass diagnosis over large populations. Some of the leading testing procedures, such as…

Quantitative Methods · Quantitative Biology 2022-08-31 Amit Solomon , Alejandro Cohen , Nir Shlezinger , Yonina C. Eldar , Muriel Médard

We study the problem of identifying defective units in a finite population of \( n \) units, where each unit \( i \) is independently defective with known probability \( p_i \). This setting is referred to as the \emph{Generalized Group…

Statistics Theory · Mathematics 2025-06-23 Yaakov Malinovsky , Viktor Skorniakov

Non-adaptive group testing involves grouping arbitrary subsets of $n$ items into different pools. Each pool is then tested and defective items are identified. A fundamental question involves minimizing the number of pools required to…

Discrete Mathematics · Computer Science 2011-07-26 Mahdi Cheraghchi , Amin Karbasi , Soheil Mohajer , Venkatesh Saligrama

In this work we study the fundamental limits of approximate recovery in the context of group testing. One of the most well-known, theoretically optimal, and easy to implement testing procedures is the non-adaptive Bernoulli group testing…

Statistics Theory · Mathematics 2021-07-30 Fotis Iliopoulos , Ilias Zadik

In probabilistic nonadaptive group testing (PGT), we aim to characterize the number of pooled tests necessary to identify a random $k$-sparse vector of defectives with high probability. Recent work has shown that $n$ tests are necessary…

Information Theory · Computer Science 2021-06-15 Larkin Flodin , Arya Mazumdar