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Population balance framework is a useful tool that can be used to describe size distribution of droplets in a liquid-liquid dispersion. Breakup and coalescence models provide closures for mathematical formulation of the population balance…

Fluid Dynamics · Physics 2015-11-25 Marcin Traczyk , Robert Sawko , Chris Thompson

We study a size-structured population model in which individual cells grow at a rate determined by a fluctuating internal variable (e.g., gene expression levels). Many previous models of phenotypically heterogeneous populations can be…

Statistical Mechanics · Physics 2026-04-06 Ethan Levien , Yaïr Hein , Farshid Jafarpour

Identifiability of evolutionary tree models has been a recent topic of discussion and some models have been shown to be non-identifiable. A coalescent-based rooted population tree model, originally proposed by Nielsen et al. 1998 [2], has…

Populations and Evolution · Quantitative Biology 2013-04-15 Arindam RoyChoudhury

Consider a continuous-state branching population constructed as a flow of nested subordinators. Inverting the subordinators and reversing time give rise to a flow of coalescing Markov processes (with negative jumps) which correspond to the…

Probability · Mathematics 2018-12-04 Clément Foucart , Chunhua Ma , Bastien Mallein

Given an evolutionary model, such as Wright--Fisher (WF) or Moran, the n-coalescent problem consists of going backward in time to find for example the time to the most recent common ancestor (MRCA) and the topology of the tree. In the…

Populations and Evolution · Quantitative Biology 2025-11-14 Bahram Houchmandzadeh

Understanding patterns of selectively neutral genetic variation is essential in order to model deviations from neutrality, caused for example by different forms of selection. Best understood is neutral genetic variation at a single locus,…

Populations and Evolution · Quantitative Biology 2012-06-13 E. Schaper , A. Eriksson , M. Rafajlovic , S. Sagitov , B. Mehlig

Distances between sequences based on their $k$-mer frequency counts can be used to reconstruct phylogenies without first computing a sequence alignment. Past work has shown that effective use of k-mer methods depends on 1) model-based…

Populations and Evolution · Quantitative Biology 2017-05-22 Chris Durden , Seth Sullivant

The Ancestral Selection Graph (ASG) is an important genealogical process which extends the well-known Kingman coalescent to incorporate natural selection. We show that the number of lineages of the ASG with and without mutation is…

Probability · Mathematics 2020-12-23 Philip A. Hanson , Paul A. Jenkins , Jere Koskela , Dario Spanò

We propose an extension of the classical $\Lambda$-Fleming-Viot model to intrinsically varying population sizes. During events, instead of replacing a proportion of the population, a random mass dies and a, possibly different, random mass…

Probability · Mathematics 2023-11-13 Julian Kern , Bastian Wiederhold

The star-shaped $\Lambda$-coalescent and corresponding $\Lambda$-Fleming-Viot process where the $\Lambda$ measure has a single atom at unity are studied in this paper. The transition functions and stationary distribution of the…

Probability · Mathematics 2016-05-10 Robert Griffiths , Shuhei Mano

We define a Markov process on the partitions of $[n]=\{1,\ldots,n\}$ by drawing a sample in $[n]$ at each time of a Poisson process, by merging blocks that contain one of these points and by leaving all other blocks unchanged. This…

Probability · Mathematics 2018-09-03 Sophie Lemaire

A stochastic system of particles is considered in which the sizes of the particles increase by successive binary mergers with the constraint that each coagulation event involves a particle with minimal size. Convergence of a suitably…

Probability · Mathematics 2011-10-31 Anne-Laure Basdevant , Philippe Laurencot , James R. Norris , Clement Rau

Spatial models where growth is limited to the edge of the expansions have been instrumental to understand the population dynamics and the clone size distribution in growing cellular populations, such as microbial colonies and avascular…

Populations and Evolution · Quantitative Biology 2022-06-08 Armin Eghdami , Jayson Paulose , Diana Fusco

When an infectious disease outbreak is of a relatively small size, describing the ancestry of a sample of infected individuals is difficult because most ancestral models assume large population sizes. Given a set of infected individuals, we…

Populations and Evolution · Quantitative Biology 2025-01-31 Xavier Didelot , David Helekal , Ian Roberts

Standard neutral population genetics theory with a strictly fixed population size has important limitations. An alternative model that allows independently fluctuating population sizes and reproduces the standard neutral evolution is…

Populations and Evolution · Quantitative Biology 2017-03-08 Thiparat Chotibut , David R. Nelson

We explore the effects of mergers on the evolution of massive early-type galaxies by modeling the evolution of their stellar populations in a hierarchical context. We investigate how a realistic red sequence population set up by z~1 evolves…

Cosmology and Nongalactic Astrophysics · Physics 2012-06-15 Rosalind E. Skelton , Eric F. Bell , Rachel S. Somerville

In this paper, we investigate the convergence of language models (LMs) trained under different random seeds, measuring convergence as the expected per-token Kullback--Leibler (KL) divergence across seeds. By comparing LM convergence as a…

Computation and Language · Computer Science 2025-10-01 Finlay Fehlauer , Kyle Mahowald , Tiago Pimentel

The correlation among the gene genealogies at different loci is crucial in biology, yet challenging to understand because such correlation depends on many factors including genetic linkage, recombination, natural selection and population…

Probability · Mathematics 2023-10-20 David Kogan , Dimitrios Diamantidis , John Wakeley , Wai-Tong Louis Fan

Cancer progression is an evolutionary process that is driven by mutation and selection in a population of tumor cells. We discuss mathematical models of cancer progression, starting from traditional multistage theory. Each stage is…

Populations and Evolution · Quantitative Biology 2011-08-31 Moritz Gerstung , Niko Beerenwinkel

The Beta coalescents are stochastic processes modeling the genealogy of a population. They appear as the rescaled limits of the genealogical trees of numerous stochastic population models. In this article, we take interest in the number of…

Probability · Mathematics 2019-05-21 Yier Lin , Bastien Mallein